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Screening compounds

Ci-1040

Also known as CI 1040, 2-((2-Chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide, 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide

CAS 212631-79-3Formula C17H14ClF2IN2O2Molar mass 478.66 g/molEC 695-548-6
GHS signal word: Warning. Pictograms: Hazardous to the environment 24 suppliers listed
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Ci-1040 chemical structure, C17H14ClF2IN2O2, CAS 212631-79-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
212631-79-3
Formula
C17H14ClF2IN2O2
Molar mass
478.66 g/mol
EC number
695-548-6
HS code
292429
Category
Screening compounds

What is Ci-1040?

Plain description, key identifiers and synonyms

2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide is an aminobenzoic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
CAS number
212631-79-3 CAS number cross-checked
EC number
695-548-6
Molecular formula
C17H14ClF2IN2O2
UNII
R3K9Y00J04
MDL number
MFCD02683961
InChIKey
GFMMXOIFOQCCGU-UHFFFAOYSA-N
InChI
InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
SMILES (canonical and isomeric)
C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl

Synonyms

  • CI 1040
  • 2-((2-Chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
  • 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
  • Benzamide, 2-((2-chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluoro-
  • Benzamide, 2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-
  • PD 184352
  • 2-(2-chloro-4-iodophenylamino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
  • 2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
  • 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
  • C.I. 1040
  • PD 184352, Free Base
  • CI-1040,PD184352
  • PD 184352CI-1040
  • 2-(2-chloro-4-iodo-anilino)-N-(cyclopropylmethoxy)-3,4-difluoro-benzamide
  • C17H14ClF2IN2O2
  • PD 184352(CI-1040)
  • Sdccgsbi-0654327.p001
  • 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040
  • CI-1040, PD184352
  • CI-1040 (PD184352)
  • CI-1040 (PD184352)?
  • US8575391, 341
  • 2-(2-Chloro4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
  • 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluoro-benzamide
  • 3,4-Difluoro-2-(2-chloro-4-iodophenylamino)-N-cyclopro pylmethoxybenzamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
478.66 g/molcalc.
Exact mass
477.9757 Dacalc.
LogP (octanol/water)
5.04calc.
Topological polar surface area
50.36 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
6calc.
Heavy atoms
25calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.24calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NOCC1CC1)c1ccccc1Nc1ccccc1

O=C(NOCC1CC1)c1ccccc1Nc1ccccc1

3 rings, 21 atoms.

2 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H400Very toxic to aquatic life.
Precautionary statements (3)
  • P273Avoid release to the environment.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ci-1040 suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 24 suppliers
24 of 24 offers
  • Abmole Bioscience Inc.
    United States, HoustonUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
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  • AChemBlock
    United States, HaywardUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
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  • Ambinter
    France, OrleansUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
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  • Angel Pharmatech Ltd.
    China, ShanghaiUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
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  • Ark Pharma Scientific Limited
    China, WuhanUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
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  • AvaChem Scientific LLC
    United StatesUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
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  • Bic Biotech
    China, NanjingUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
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  • BioChemPartner
    China, ShangHaiUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
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  • BioCrick
    China, ChengduUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
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  • Capot
    China, HangzhouUnclaimed profile
    Ci-1040Grade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

24 suppliers in 4 countries

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Ci-1040 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antineoplastic agent
  • pharmaceutical

Pharmacology

MEK Inhibitor CI-1040 is an agent that inhibits both mitogen-activated protein kinase kinases 1 and 2 (MEK1 and MEK2), substrates of Raf and phosphorylates extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), preventing phosphorylation and activation of the Mitogen-Activated Protein Kinase (MAPK) pathways, involved with signal transduction pathways and tumor proliferation.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ci-1040 is traded under.

HS 2924.29Indicative HS code

Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$5.69B
−5.1% vs 2023, imports $5.8B
2019 to 2024
Top exporters
  1. China32.3%
  2. Switzerland * partner reported13.6%
  3. Norway * partner reported12.8%
Top importers
  1. United States15.9%
  2. Ireland15.8%
  3. Germany11.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ci-1040 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ci-1040, based on the data on this page

What is Ci-1040?

2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide is an aminobenzoic acid.

What is the CAS number of Ci-1040?

The CAS registry number of Ci-1040 is 212631-79-3.

What is the molecular formula and weight of Ci-1040?

The molecular formula of Ci-1040 is C17H14ClF2IN2O2 and its molar mass is 478.66 g/mol.

What is Ci-1040 used for?

Known uses and roles of Ci-1040 include building blocks in research and laboratory, screening compounds in research and laboratory, antineoplastic agent and pharmaceutical.

Is Ci-1040 hazardous?

Ci-1040 carries the GHS signal word "Warning". Main hazards: very toxic to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ci-1040?

Ci-1040 is usually classified under HS code 292429 (Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ci-1040?

CompoundList lists 24 suppliers of Ci-1040 in China, United States, Canada and France. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ci-1040?

Suppliers quote Ci-1040 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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