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Impurities and reference standards

Codeinone

Also known as 6-Codeinone, 3-methoxy-17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-6-one, (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one

CAS 467-13-0Formula C18H19NO3Molar mass 297.35 g/molEC 207-386-1
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant 2 suppliers listed
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Codeinone chemical structure, C18H19NO3, CAS 467-13-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
467-13-0
Formula
C18H19NO3
Molar mass
297.35 g/mol
EC number
207-386-1
HS code
293499
Category
Impurities and reference standards

What is Codeinone?

Plain description, key identifiers and synonyms

Codeinone is an isoquinoline alkaloid. It is functionally related to a morphine. It is a conjugate base of a codeinone(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
CAS number
467-13-0 CAS number cross-checked
EC numbers
207-386-1, 935-619-3
Molecular formula
C18H19NO3
UNII
22B5AW0ANN
InChIKey
XYYVYLMBEZUESM-CMKMFDCUSA-N
InChI
InChI=1S/C18H19NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-12,17H,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1
Canonical SMILES
COc1ccc2c3c1OC1C(=O)C=CC4C(C2)N(C)CCC314
Isomeric SMILES
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)C=C4

Synonyms

  • 6-Codeinone
  • 3-methoxy-17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-6-one
  • (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
  • (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro(3,2-e)isoquinolin-7-one
  • (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro(3,2-e)isoquinoline-7-one
  • (5alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-one
  • 4-27-00-03599 (Beilstein Handbook Reference)
  • Morphinan-6-one, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-
  • 6-Oxocodeine
  • Morphinan-6-one, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5-alpha)-
  • Codeinone (1.0mg/ml in Acetonitrile)
  • (-)-Codeinone
  • (-)-Co deinone
  • Codeine Impurity 17
  • Codeine monohydrate impurity i
  • 7,8-Didehydro-4,5a-epoxy-3-methoxy-17-methyl-morphinan-6-one
  • Codeine hydrochloride dihydrate impurity i
  • Codeine phosphate hemihydrate impurity i
  • (5a)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methyl-morphinan-6-one
  • 3-Methoxy-17-methyl-5alpha-7,8-didehydro-4,5-epoxymorphinan-6-one
  • Hydrocodone hydrogen tartrate 2.5-hydrate impurity e
  • Morphinan-6-one, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5.alpha.)-
  • Morphinan-6-one, 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methyl-
  • (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-2,3,4,4a-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
297.35 g/molcalc.
Exact mass
297.1365 Dacalc.
LogP (octanol/water)
1.71calc.
Topological polar surface area
38.77 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
1calc.
Heavy atoms
22calc.
Rings
5calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CC2C3Cc4cccc5c4C2(CCN3)C1O5

O=C1C=CC2C3Cc4cccc5c4C2(CCN3)C1O5

5 rings, 19 atoms.

29 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H301Toxic if swallowed.
  • H302Harmful if swallowed.
  • H331Toxic if inhaled.
Precautionary statements (13)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Codeinone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 2 suppliers
  • Chemical Point
    GermanyUnclaimed profile
    CodeinoneGrade, purity and minimum order on request
    Price on request
    View
  • Veeprho
    Czech Republic, Czech RepublicUnclaimed profile
    CodeinoneGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

2 suppliers in 2 countries

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Codeinone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Codeinone is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Codeinone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Codeinone, based on the data on this page

What is Codeinone?

Codeinone is an isoquinoline alkaloid. It is functionally related to a morphine. It is a conjugate base of a codeinone(1+).

What is the CAS number of Codeinone?

The CAS registry number of Codeinone is 467-13-0.

What is the molecular formula and weight of Codeinone?

The molecular formula of Codeinone is C18H19NO3 and its molar mass is 297.35 g/mol.

Is Codeinone hazardous?

Codeinone carries the GHS signal word "Danger". Main hazards: toxic if swallowed, harmful if swallowed, toxic if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Codeinone?

Codeinone is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Codeinone?

CompoundList lists 2 suppliers of Codeinone in Czech Republic and Germany. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Codeinone?

Suppliers quote Codeinone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Codeinone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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