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Screening compounds

Cphpc

Also known as Miridesap, Ro 63-8695, 1,1'-hexanedioyldi-D-proline

CAS 224624-80-0Formula C16H24N2O6Molar mass 340.38 g/molEC 827-375-0
GHS signal word: Danger. Pictograms: Corrosive, Harmful or irritant 2 suppliers listed
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Cphpc chemical structure, C16H24N2O6, CAS 224624-80-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
224624-80-0
Formula
C16H24N2O6
Molar mass
340.38 g/mol
EC number
827-375-0
HS code
293399
Category
Screening compounds

What is Cphpc?

Plain description, key identifiers and synonyms

Miridesap is a small molecule compound that depletes serum amyloid P component (SAP), with potential anti-amyloid activity. Upon injection, miridesap binds to circulating SAP, forming complexes that are rapidly cleared in the liver. SAP bound to amyloid deposits is in equilibrium with plasma SAP, and depletion of the latter should lead to the eventual removal of SAP from amyloid deposits as well. SAP is a universal component of amyloid deposits and contributes to the pathogenesis of amyloidosis.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxohexanoyl]pyrrolidine-2-carboxylic acid
CAS number
224624-80-0 CAS number cross-checked
EC number
827-375-0
Molecular formula
C16H24N2O6
UNII
WO97N24A47
MDL number
MFCD09970762
InChIKey
HZLAWYIBLZNRFZ-VXGBXAGGSA-N
InChI
InChI=1S/C16H24N2O6/c19-13(17-9-3-5-11(17)15(21)22)7-1-2-8-14(20)18-10-4-6-12(18)16(23)24/h11-12H,1-10H2,(H,21,22)(H,23,24)/t11-,12-/m1/s1
Canonical SMILES
O=C(O)C1CCCN1C(=O)CCCCC(=O)N1CCCC1C(=O)O
Isomeric SMILES
C1C[C@@H](N(C1)C(=O)CCCCC(=O)N2CCC[C@@H]2C(=O)O)C(=O)O

Synonyms

  • Miridesap
  • Ro 63-8695
  • 1,1'-hexanedioyldi-D-proline
  • (2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxohexanoyl]pyrrolidine-2-carboxylic acid
  • (2R)-1-{6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxohexanoyl}pyrrolidine-2-carboxylic acid
  • miridesapum
  • (2R)-1-(6-((2R)-2-carboxypyrrolidin-1-yl)-6-oxohexanoyl)pyrrolidine-2-carboxylic acid
  • GSK 2315698
  • CPOHPC acid
  • 4avt
  • (2'R)-adipoyldi-D-proline
  • (2R,2'R)-1,1'-Adipoylbis(pyrrolidine-2-carboxylic acid)
  • 1,1'-(1,6-Dioxo-1,6-hexanediyl)bis-D-proline
  • D-Proline, 1,1'-(1,6-dioxo-1,6-hexanediyl)bis-
  • (R)-1-[6-[(R)-2-carboxy-pyrrolidin-1-yl]-6-oxo-hexanoyl]-pyrrolidine-2-carboxylic acid
  • (2r)-1-[6-[(2r)-2-Carboxypyrrolidin-1-Yl]-6-Oxidanylidene-Hexanoyl]pyrrolidine-2-Carboxylic Acid
  • Ro-63-8695
  • CPHPC(Miridesap)
  • GHE
  • CPHPC(Miridesap)?
  • Miridesap (USAN/INN)
  • compound 52
  • R-1-(6-(R-2-carboxypyrrolidin-1-yl)-6-oxohexanoyl)pyrrolidine-2-carboxylic acid
  • Ro 63-8695|GSK2315698
  • Phenethylamine, N-(2-hydroxyethyl)-alpha-methyl
Show all 32 synonyms
  • 1,1'-(1,6-Dioxo-1,6-hexanediyl)bis(D-proline
  • (2R,2'R)-1,1'-Adipoylbis(pyrrolidine-2-carboxylicacid)
  • Carboxy pyrrolidine hexanoyl pyrrolidine carboxylate
  • D-Proline, 1,1'-(1,6-dioxo-1,6-hexanediyl)bis
  • (2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxo-hexanoyl]pyrrolidine-2-carboxylic acid
  • (2R,2'R)-1,1'-(1,6-Dioxo-1,6-hexanediyl)di(2-pyrrolidinecarboxylic acid)
  • r-1-[6-[r-2-carboxy-pyrrolidin-1-yl]-6-oxo-hexanoyl] pyrrolidine-2-carboxylic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
340.38 g/molcalc.
Exact mass
340.1634 Dacalc.
LogP (octanol/water)
0.7calc.
Topological polar surface area
115.2 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
7calc.
Heavy atoms
24calc.
Rings
2calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.75calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CCCCC(=O)N1CCCC1)N1CCCC1

O=C(CCCCC(=O)N1CCCC1)N1CCCC1

2 rings, 18 atoms, the 1,6-Bis(1-pyrrolidinyl)-1,6-hexanedione ring system.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H314Causes severe skin burns and eye damage.
  • H318Causes serious eye damage.
Precautionary statements (17)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P363Wash contaminated clothing before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Cphpc suppliers

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All 2 suppliers

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Where suppliers are based

2 suppliers in 2 countries

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Cphpc price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anti-HIV agent
  • antimicrobial agent
  • antiviral agent

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cphpc is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Cphpc is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cphpc, based on the data on this page

What is Cphpc?

Miridesap is a small molecule compound that depletes serum amyloid P component (SAP), with potential anti-amyloid activity. Upon injection, miridesap binds to circulating SAP, forming complexes that are rapidly cleared in the liver.

What is the CAS number of Cphpc?

The CAS registry number of Cphpc is 224624-80-0.

What is the molecular formula and weight of Cphpc?

The molecular formula of Cphpc is C16H24N2O6 and its molar mass is 340.38 g/mol.

What is Cphpc used for?

Known uses and roles of Cphpc include building blocks in research and laboratory, screening compounds in research and laboratory, anti-hiv agent, antimicrobial agent and antiviral agent.

Is Cphpc hazardous?

Cphpc carries the GHS signal word "Danger". Main hazards: harmful if swallowed, causes severe skin burns and eye damage, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Cphpc?

Cphpc is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cphpc?

CompoundList lists 2 suppliers of Cphpc in China and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Cphpc?

Suppliers quote Cphpc on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Cphpc

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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