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Alkaloids

Cyclopamine

Also known as 11-Deoxojervine, 11-Deoxyjervine, Alkaloid V

CAS 4449-51-8Formula C27H41NO2Molar mass 411.63 g/molEC 628-058-8
GHS signal word: Warning. Pictograms: Serious health hazard 49 suppliers listed
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Cyclopamine chemical structure, C27H41NO2, CAS 4449-51-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
4449-51-8
Formula
C27H41NO2
Molar mass
411.63 g/mol
EC number
628-058-8
HS code
293979
Category
Alkaloids

What is Cyclopamine?

Plain description, key identifiers and synonyms

Cyclopamine is a member of piperidines. It has a role as a glioma-associated oncogene inhibitor.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3',6',10,11b-tetramethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3-ol
CAS number
4449-51-8 CAS number cross-checkedOther or deprecated CAS: 11051-96-0
EC number
628-058-8
Molecular formula
C27H41NO2
UNII
ZH658AJ192
MDL number
MFCD09878269
InChIKey
QASFUMOKHFSJGL-LAFRSMQTSA-N
InChI
InChI=1S/C27H41NO2/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2/h5,15,17,19-21,23-25,28-29H,6-14H2,1-4H3/t15-,17+,19-,20-,21-,23-,24+,25-,26-,27-/m0/s1
Canonical SMILES
CC1=C2CC3C(CC=C4CC(O)CCC43C)C2CCC12OC1CC(C)CNC1C2C
Isomeric SMILES
C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5CC4=C3C)C)O)C)NC1

Synonyms

  • 11-Deoxojervine
  • 11-Deoxyjervine
  • Alkaloid V
  • Veratraman-3-ol, 17,23-epoxy-, (3beta,23beta)-
  • (3beta23R)-17,23-Epoxyveratraman-3-ol
  • 3,4'-Dinitroflavone
  • Jervine, 11-deoxo-
  • Cyclopamine Tartrate
  • Cyclop
  • Cyclopamine?
  • Cyclopamine (Standard)
  • Cyclopamine11-Deoxyjervine, Jervine, 11-deoxo-
  • (3beta,22S,23R)-17,23-epoxyveratraman-3-ol
  • Veratraman-3-ol,23-epoxy-, (3-beta,23-beta)-
  • (22S,23R)-17beta-17,23-Epoxyveratraman-3beta-ol
  • Veratraman-3-ol, 17,23-epoxy-, (3-beta,23-beta)-
  • (3alpha,8alpha,14beta,22S,23R)-17,23-epoxyveratraman-3-ol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
411.63 g/molcalc.
Exact mass
411.3137 Dacalc.
LogP (octanol/water)
5calc.
Topological polar surface area
41.49 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
0calc.
Heavy atoms
30calc.
Rings
6calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.85calc.
Formal charge
0calc.
Stereocentres
10calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=C2CC3C4CCCCC4=CCC3C2CCC12CC1NCCCC1O2

C1=C2CC3C4CCCCC4=CCC3C2CCC12CC1NCCCC1O2

6 rings, 25 atoms.

8 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H341Suspected of causing genetic defects.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Cyclopamine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 49 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

49 suppliers in 13 countries

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Cyclopamine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • glioma-associated oncogene inhibitor

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Cyclopamine is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Cyclopamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Cyclopamine, based on the data on this page

What is Cyclopamine?

Cyclopamine is a member of piperidines. It has a role as a glioma-associated oncogene inhibitor.

What is the CAS number of Cyclopamine?

The CAS registry number of Cyclopamine is 4449-51-8. Other or deprecated CAS numbers: 11051-96-0.

What is the molecular formula and weight of Cyclopamine?

The molecular formula of Cyclopamine is C27H41NO2 and its molar mass is 411.63 g/mol.

What is Cyclopamine used for?

Known uses and roles of Cyclopamine include glioma-associated oncogene inhibitor.

Is Cyclopamine hazardous?

Cyclopamine carries the GHS signal word "Warning". Main hazards: suspected of causing genetic defects, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Cyclopamine?

Cyclopamine is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Cyclopamine?

CompoundList lists 49 suppliers of Cyclopamine in United States, China, Germany, Spain and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Cyclopamine in India?

1 supplier in India list Cyclopamine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Cyclopamine?

Suppliers quote Cyclopamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Cyclopamine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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