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Central nervous system drugs

Deferiprone

Also known as 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone, Ferriprox, 3-hydroxy-1,2-dimethylpyridin-4(1H)-one

CAS 30652-11-0Formula C7H9NO2Molar mass 139.15 g/molEC 629-275-0
GHS signal word: Warning. Pictograms: Harmful or irritant 116 suppliers listed Drug substance
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Deferiprone chemical structure, C7H9NO2, CAS 30652-11-0
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Needles from water
Melting point
266 to 268
Solubility
Solubility at 37 °C: water approx 20 mg/mL (pH 7.4)
HS code
293339
Category
Central nervous system drugs
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Deferiprone?

Plain description, key identifiers and synonyms

Deferiprone is a member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia. It has a role as an iron chelator and a protective agent.

Deferiprone is an iron chelator.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-hydroxy-1,2-dimethylpyridin-4-one
CAS number
30652-11-0 CAS number cross-checked
EC number
629-275-0
Molecular formula
C7H9NO2
UNII
2BTY8KH53L
MDL number
MFCD00134497
INCI name
DEFERIPRONE
InChIKey
TZXKOCQBRNJULO-UHFFFAOYSA-N
InChI
InChI=1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3
SMILES (canonical and isomeric)
CC1=C(C(=O)C=CN1C)O

Synonyms

  • 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
  • Ferriprox
  • 3-hydroxy-1,2-dimethylpyridin-4(1H)-one
  • 1,2-Dimethyl-3-hydroxypyrid-4-one
  • 4(1H)-Pyridinone, 3-hydroxy-1,2-dimethyl-
  • 3-hydroxy-1,2-dimethylpyridin-4-one
  • Deferiprona
  • Deferipron
  • 1,2-Dimethyl-3-hydroxy-4(1H)-pyridinone
  • 4(1H)-Pyridinone, 1,2-dimethyl-3-hydroxy-
  • 1,2-dimethyl-3-hydroxy-4-pyridinone
  • 3-Hydroxy-1,2-dimethyl-4-pyridinone
  • 4(1H)-Pyridone, 3-hydroxy-1,2-dimethyl-
  • Dmohpo
  • HDMPP
  • Deferipronum
  • 1,2 Dimethyl 3 hydroxypyrid 4 one
  • 1,2-dimethyl-3-hydroxypyridin-4-one
  • 1,2 Dimethyl 3 hydroxy 4 pyridinone
  • 1,2 Dimethyl 3 hydroxypyridin 4 one
  • 3 Hydroxy 1,2 dimethyl 4 pyridinone
  • 3-hydroxy-1,2-dimethyl-4(1H)-pyridinone
  • Deferiprone (INN)
  • 1,2-dimethyl-3-hydroxy-4-pyridone
  • 3-hydroxy-1,2-dimethylpyrid-4-one
Show all 34 synonyms
  • 3-hydroxy-1,2-dimethyl-pyridin-4-one
  • 1,2-Dimethyl-3-hydroxypyridine-4-one
  • CP20 (Chelating agent)
  • Ferriprox (TN)
  • 3-hydroxy-1,2-dimethylhydropyridin-4-one
  • Deferum
  • Deferiprone CRS
  • Deferiprone (Standard)
  • Deferiprone (USAN/INN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Needles from waterexp.
Taste
Very bitter tasteexp.
Melting point
266 to 268exp.
Solubility
Solubility at 37 °C: water approx 20 mg/mL (pH 7.4)exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
139.15 g/molcalc.
Exact mass
139.0633 Dacalc.
LogP (octanol/water)
0.4calc.
Topological polar surface area
42.23 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
10calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.29calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1cc[nH]cc1

O=c1cc[nH]cc1

1 ring, 7 atoms, the 4-Hydroxypyridine ring system.

2,433 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Deferiprone suppliers

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All 116 suppliers
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Where suppliers are based

116 suppliers in 17 countries

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Deferiprone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Iron Chelating Agents.

Cosmetic ingredient, INCI name DEFERIPRONE(chelating)

Pharmacological actions

  • Iron Chelating Agents

Roles

  • anti-HIV agent
  • anti-anaemic agent
  • antidyskinesia agent
  • antimicrobial agent
  • antiparkinson drug
  • antiviral agent
  • cardiovascular drug
  • chelator
  • iron chelator
  • ligand
  • pharmaceutical
  • protective agent
  • renoprotective agent

Cosmetic functions

  • Chelating

Pharmacology

Deferiprone is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Deferiprone is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Deferiprone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Deferiprone, based on the data on this page

What is Deferiprone?

Deferiprone is a member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia. It has a role as an iron chelator and a protective agent.

What is the CAS number of Deferiprone?

The CAS registry number of Deferiprone is 30652-11-0.

What is the molecular formula and weight of Deferiprone?

The molecular formula of Deferiprone is C7H9NO2 and its molar mass is 139.15 g/mol.

What is Deferiprone used for?

Iron Chelating Agents.

Is Deferiprone hazardous?

Deferiprone carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Deferiprone?

Deferiprone is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Deferiprone?

CompoundList lists 116 suppliers of Deferiprone in United States, China, India, United Kingdom and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Deferiprone in India?

10 suppliers in India list Deferiprone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Deferiprone?

Suppliers quote Deferiprone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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