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Central nervous system drugs

Desflurane

Also known as Suprane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane, Desflurano

CAS 57041-67-5Formula C3H2F6OMolar mass 168.04 g/molEC 688-023-8
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 45 suppliers listed Drug substance
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Desflurane chemical structure, C3H2F6O, CAS 57041-67-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Liquid
Boiling point
23.5 °C
Density
Relative density (water = 1): 1.5
Solubility
Solubility in water: poor
HS code
290919
Category
Central nervous system drugs
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Desflurane?

Plain description, key identifiers and synonyms

Desflurane is an organofluorine compound. It has a role as an inhalation anaesthetic. It is functionally related to a methoxyethane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane
CAS number
57041-67-5 CAS number cross-checked
EC number
688-023-8
Molecular formula
C3H2F6O
UNII
CRS35BZ94Q
MDL number
MFCD00236716
InChIKey
DPYMFVXJLLWWEU-UHFFFAOYSA-N
InChI
InChI=1S/C3H2F6O/c4-1(3(7,8)9)10-2(5)6/h1-2H
SMILES (canonical and isomeric)
C(C(F)(F)F)(OC(F)F)F

Synonyms

  • Suprane
  • 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane
  • Desflurano
  • difluoromethyl 1,2,2,2-tetrafluoroethyl ether
  • Desfluranum
  • (+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether
  • 1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane
  • Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-
  • Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-, (+-)-
  • Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-,(+-)-
  • 1,2,2,2-Tetrafluoroethyl difluoromethyl ether
  • (+/-)-2-difluoromethyl 1,2,2,2-tetrafluoroethyl ether
  • (2RS)-2-(Difluoromethoxy)-1,1,1,2-tetrafluoroethane
  • Suprane (TN)
  • Desflurane (JAN/USP/INN)
  • Desfluran-O
  • Chf2ochfcf3
  • Ethane,2-(difluoromethoxy)-1,1,1,2-tetrafluoro-
  • 1H,3H-Perfluoro(2-oxabutane)
  • 1-(difluoromethoxy)-1,2,2,2-tetrafluoroethane
  • Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-, (+/-)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Liquidexp.
Odour
Slight non-pungent odorexp.
Boiling point
23.5 °Cexp.
Density
Relative density (water = 1): 1.5exp.
Solubility
Solubility in water: poorexp.
Vapour pressure
88.53 kPa at 20 °C, approximately 700 mm Hg at 22-23 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
168.04 g/molcalc.
Exact mass
168.001 Dacalc.
LogP (octanol/water)
2.08calc.
Topological polar surface area
9.23 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
10calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H336May cause drowsiness or dizziness.
  • H360May damage fertility or the unborn child.
  • H361Suspected of damaging fertility or the unborn child.
  • H361fdSuspected of damaging fertility. Suspected of damaging the unborn child.
  • H373May cause damage to organs through prolonged or repeated exposure.
Precautionary statements (19)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Desflurane suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 45 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

45 suppliers in 11 countries

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Desflurane price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Anesthetics, Inhalation

Roles

  • anaesthetic
  • general anaesthetic
  • inhalation anaesthetic
  • pharmaceutical

Pharmacology

Desflurane is a General Anesthetic. The physiologic effect of desflurane is by means of General Anesthesia.

How it is made

Preparation and use as anesthetic: R.C. Terrell, US 4762856 (1988 to BOC)

Prepared but not claimed: J.P. Russell, et al., US 3897502 (1975 to Airco)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Desflurane is traded under.

HS 2909.19Indicative HS code

Acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives…

World exports in 2024
$10.2B
−8.7% vs 2023, imports $10.4B
2019 to 2024
Top exporters
  1. United States32.0%
  2. China22.3%
  3. Saudi Arabia12.9%
Top importers
  1. Singapore16.5%
  2. Mexico14.8%
  3. Japan14.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Desflurane is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Desflurane, based on the data on this page

What is Desflurane?

Desflurane is an organofluorine compound. It has a role as an inhalation anaesthetic. It is functionally related to a methoxyethane.

What is the CAS number of Desflurane?

The CAS registry number of Desflurane is 57041-67-5.

What is the molecular formula and weight of Desflurane?

The molecular formula of Desflurane is C3H2F6O and its molar mass is 168.04 g/mol.

What is Desflurane used for?

Known uses and roles of Desflurane include cns agents in pharmaceuticals, anaesthetic, general anaesthetic, inhalation anaesthetic, pharmaceutical and 1 more.

Is Desflurane hazardous?

Desflurane carries the GHS signal word "Danger". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Desflurane?

Desflurane is usually classified under HS code 290919 (Acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Desflurane?

CompoundList lists 45 suppliers of Desflurane in China, United States, Germany, Spain and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Desflurane?

Suppliers quote Desflurane on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Desflurane

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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