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Heterocyclic building blocks

Dexlofexidine

Also known as Dexlofexidinum, Lofexidine, (s)-, dexlofexidina

CAS 81447-79-2Formula C11H12Cl2N2OMolar mass 259.14 g/mol
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Dexlofexidine chemical structure, C11H12Cl2N2O, CAS 81447-79-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
81447-79-2
Formula
C11H12Cl2N2O
Molar mass
259.14 g/mol
HS code
293329
Category
Heterocyclic building blocks

What is Dexlofexidine?

Plain description, key identifiers and synonyms

Dexlofexidine is a chemical substance with the molecular formula C11H12Cl2N2O and a molar mass of 259.14 g/mol. Its CAS registry number is 81447-79-2. The IUPAC name is 2-[(1S)-1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[(1S)-1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole
CAS number
81447-79-2 CAS number cross-checked
Molecular formula
C11H12Cl2N2O
UNII
VXJ7Z24RN1
InChIKey
KSMAGQUYOIHWFS-ZETCQYMHSA-N
InChI
InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)/t7-/m0/s1
Canonical SMILES
CC(Oc1c(Cl)cccc1Cl)C1=NCCN1
Isomeric SMILES
C[C@@H](C1=NCCN1)OC2=C(C=CC=C2Cl)Cl

Synonyms

  • Dexlofexidinum
  • Lofexidine, (s)-
  • dexlofexidina
  • (+)-(S)-2-(1-(2,6-Dichlorophenoxy)ethyl)-2-imidazoline
  • (S)-Lofexidine
  • 2-[(1S)-1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole
  • (S)-2-(1-(2,6-Dichlorophenoxy)ethyl)-4,5-dihydro-1H-imidazole
  • (+)-Lofexidine, (S)-(+)-Lofexidine
  • (S)-2-(1-(2,6-Dichlorophenoxy)ethyl)-2-imidazoline

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
259.14 g/molcalc.
Exact mass
258.0327 Dacalc.
LogP (octanol/water)
2.76calc.
Topological polar surface area
33.62 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
3calc.
Heavy atoms
16calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.36calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(OCC2=NCCN2)cc1

c1ccc(OCC2=NCCN2)cc1

2 rings, 13 atoms, the 2-(Phenoxymethyl)-4,5-dihydro-1H-imidazole ring system.

49 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Dexlofexidine suppliers

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Dexlofexidine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dexlofexidine is traded under.

HS 2933.29Indicative HS code

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…

World exports in 2024
$1.43B
−7.6% vs 2023, imports $1.47B
2019 to 2024
Top exporters
  1. China28.1%
  2. France * partner reported12.7%
  3. India * partner reported10.3%
Top importers
  1. United Kingdom13.0%
  2. United States7.9%
  3. China6.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Dexlofexidine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dexlofexidine, based on the data on this page

What is Dexlofexidine?

Dexlofexidine is a chemical substance with the molecular formula C11H12Cl2N2O and a molar mass of 259.14 g/mol. Its CAS registry number is 81447-79-2. The IUPAC name is 2-[(1S)-1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole.

What is the CAS number of Dexlofexidine?

The CAS registry number of Dexlofexidine is 81447-79-2.

What is the molecular formula and weight of Dexlofexidine?

The molecular formula of Dexlofexidine is C11H12Cl2N2O and its molar mass is 259.14 g/mol.

What is Dexlofexidine used for?

Known uses and roles of Dexlofexidine include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Dexlofexidine hazardous?

No GHS hazard classification for Dexlofexidine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Dexlofexidine?

Dexlofexidine is usually classified under HS code 293329 (Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dexlofexidine?

Post a free request on CompoundList and suppliers of Dexlofexidine will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Dexlofexidine?

Suppliers quote Dexlofexidine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dexlofexidine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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