Dobutamine
Also known as DL-dobutamine, Dobutamina, racemic-Dobutamine
Key facts
What buyers check first
- CAS number
- 34368-04-2
- Formula
- C18H23NO3
- Molar mass
- 301.39 g/mol
- EC number
- 112-679-1
- HS code
- 292229
- Category
- Cardiovascular and metabolic drugs
What is Dobutamine?
Plain description, key identifiers and synonyms
Dobutamine is a catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure. It has a role as a beta-adrenergic agonist, a sympathomimetic agent and a cardiotonic drug. It is a secondary amine and a catecholamine.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol
- CAS number
- 34368-04-2 CAS number cross-checked
- EC number
- 112-679-1
- Molecular formula
- C18H23NO3
- UNII
- 3S12J47372
- MDL number
- MFCD00072085
- InChIKey
- JRWZLRBJNMZMFE-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H23NO3/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15/h4-9,12-13,19-22H,2-3,10-11H2,1H3
- SMILES (canonical and isomeric)
- CC(CCC1=CC=C(C=C1)O)NCCC2=CC(=C(C=C2)O)O
Synonyms
- DL-dobutamine
- Dobutamina
- racemic-Dobutamine
- Dobutaminum
- Racemic dobutamine
- rac-dobutamine
- Compound 81929
- 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol
- 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
- (+-)-4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
- 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
- 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol
- 1,2-Benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, (+-)-
- 4-(2-(4-(4-hydroxyphenyl)butan-2-ylamino)ethyl)benzene-1,2-diol
- 3,4-dihydroxy-N-(3-(4-hydroxyphenyl)-1-methylpropyl)-beta-phenylethylamine
- 4-(2-((4-(4-Hydroxyphenyl)butan-2-yl)amino)ethyl)benzene-1,2-diol
- 4-(2-(3-(4-Hydroxy-phenyl)-1-methyl-propylamino)-ethyl)-benzene-1,2-diol
- Dobutamin ratiopharm
- Tartrate, Dobutamine
- Hydrobromide, Dobutamine
- Lactobionate, Dobutamine
- 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol
- (+/-)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
- 4-[2-[[3-(4-hydroxyphenyl)-1-methyl-propyl]amino]ethyl]benzene-1,2-diol
- (+/-)-dobutamine
Show all 29 synonymsShow fewer synonyms
- LY 81929
- 4-(2-((3-(4-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)-1,2-benzenediol
- 1,2-Benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-
- Dobutamine (USAN/INN)
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 301.39 g/molcalc.Computed value |
|---|---|
| Exact mass | 301.1678 Dacalc.Computed value |
| LogP (octanol/water) | 2.96calc.Computed value |
| Topological polar surface area | 72.72 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 4calc.Computed value |
| Hydrogen bond acceptors | 4calc.Computed value |
| Rotatable bonds | 7calc.Computed value |
| Heavy atoms | 22calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.33calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 1calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302 + H312 + H332Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.
- H302Harmful if swallowed.
- H312Harmful in contact with skin.
- H332Harmful if inhaled.
- H361fdSuspected of damaging fertility. Suspected of damaging the unborn child.
Precautionary statements (16)
- P203Obtain, read and follow all safety instructions before use.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P317Get medical help.
- P318If exposed or concerned, get medical advice.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidDobutamine suppliers
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- India, NoidaUnclaimed profileDobutamineGrade, purity and minimum order on requestPrice on request
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- India, Yadadri Bhuvanagiri ManufacturerUnclaimed profileDobutamineGrade, purity and minimum order on requestPrice on request
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- India ManufacturerUnclaimed profileDobutamineGrade, purity and minimum order on requestPrice on request
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- India ManufacturerUnclaimed profileDobutamineGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
49 suppliers in 12 countries
- United States15
- China10
- India8
- United Kingdom3
- Germany2
- Spain2
- and 6 more countries
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Dobutamine price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Pharmaceuticals.
Industries and functions
Pharmacological actions
- Adrenergic beta-1 Receptor Agonists
- Cardiotonic Agents
- Sympathomimetics
Roles
- adrenergic agent
- adrenergic agonist
- beta-adrenergic agonist
- beta-adrenergic drug
- cardiotonic drug
- cardiovascular drug
- neuroprotective agent
- neurotransmitter agent
- pharmaceutical
- protective agent
- sympathomimetic agent
Pharmacology
Dobutamine is a beta-Adrenergic Agonist. The mechanism of action of dobutamine is as an Adrenergic beta-Agonist.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Dobutamine is traded under.
Amino-naphthols and other amino-phenols, other than those containing more than one kindโฆ
- India * partner reported25.8%
- United States14.4%
- South Korea7.6%
* Partner reported figures, a lower bound.
The HS code shown for Dobutamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Dobutamine, based on the data on this page
What is Dobutamine?
What is the CAS number of Dobutamine?
What is the molecular formula and weight of Dobutamine?
What is Dobutamine used for?
Is Dobutamine hazardous?
What is the HS code of Dobutamine?
Where can I buy Dobutamine?
Where can I buy Dobutamine in India?
What is the price of Dobutamine?
Guides for buyers
Practical guides that help when you source, ship or handle Dobutamine
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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