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Hormones and steroids

Dromostanolone

Also known as Drostanolone, Metholone, Medrotestron

CAS 58-19-5Formula C20H32O2Molar mass 304.47 g/molEC 200-367-9
GHS signal word: Danger. Pictograms: Serious health hazard
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Dromostanolone chemical structure, C20H32O2, CAS 58-19-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
58-19-5
Formula
C20H32O2
Appearance
Crystals from acetone/hexane
Melting point
149 to 153
HS code
293729
Category
Hormones and steroids
Illustrative photo, drums, an IBC tote and sacks in a chemical warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Dromostanolone?

Plain description, key identifiers and synonyms

Metholone is a 3-oxo-5alpha-steroid, a 17beta-hydroxy steroid and an anabolic androgenic steroid. It has a role as an antineoplastic agent and an anabolic agent.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
CAS number
58-19-5 CAS number cross-checked
EC number
200-367-9
Molecular formula
C20H32O2
UNII
7DR7H00HDT
InChIKey
IKXILDNPCZPPRV-RFMGOVQKSA-N
InChI
InChI=1S/C20H32O2/c1-12-11-20(3)13(10-17(12)21)4-5-14-15-6-7-18(22)19(15,2)9-8-16(14)20/h12-16,18,22H,4-11H2,1-3H3/t12-,13+,14+,15+,16+,18+,19+,20+/m1/s1
Canonical SMILES
CC1CC2(C)C(CCC3C4CCC(O)C4(C)CCC32)CC1=O
Isomeric SMILES
C[C@@H]1C[C@]2([C@@H](CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C)CC1=O)C

Synonyms

  • Drostanolone
  • Metholone
  • Medrotestron
  • Medrosteron
  • Drostanolona
  • Drostanolonum
  • 2alpha-Methyldihydrotestosterone
  • Dihydro-2alpha-methyltestosterone
  • 17beta-Hydroxy-2alpha-methyl-5alpha-androstan-3-one
  • 5alpha-Androstan-3-one, 17beta-hydroxy-2alpha-methyl-
  • Androstan-3-one, 17-hydroxy-2-methyl-, (2alpha,5alpha,17beta)-
  • drostanolon
  • (1S,2S,4R,7S,10R,11S,14S,15S)-14-hydroxy-2,4,15-trimethyltetracyclo(8.7.0.0^(2,7).0^(11,15))heptadecan-5-one
  • (1S,2S,4R,7S,10R,11S,14S,15S)-14-hydroxy-2,4,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one
  • 17 beta-hydroxy-2 alpha-methyl-5 alpha-androstan-3-one
  • 2 Alpha-methyldihydrotestosterone
  • 2 Alpha-methylandrostan-17 beta-ol-3-one
  • 2 Alpha-5 alpha-17 beta-17-hydroxy-2-methyl-androstan-3-one
  • (1S,2S,4R,7S,10R,11S,14S,15S)-14-hydroxy-2,4,15-trimethyltetracyclo(8.7.0.02,7.011,15)heptadecan-5-one
  • SKI 27719
  • 5-alpha-Androstan-3-one, 17-beta-hydroxy-2-alpha-methyl-
  • (2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
  • Drostanolo
  • Methalone
  • Drostanolone (1.0 mg/mL in Acetonitrile)
Show all 31 synonyms
  • 2-alpha-Methyldihydrotestosterone
  • Dihydro-2-alpha-methyltestosterone
  • Testosterone, 4,5alpha-dihydro-2alpha-methyl-
  • 17-beta-Hydroxy-2-alpha-methyl-5-alpha-androstan-3-one
  • 2-alpha-Methyl-17-beta-hydroxy-5-alpha-androstan-3-one
  • Androstan-3-one, 17-hydroxy-2-methyl-, (2-alpha,5-alpha,17-beta)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from acetone/hexaneexp.
Melting point
149 to 153exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
304.47 g/molcalc.
Exact mass
304.2402 Dacalc.
LogP (octanol/water)
4.21calc.
Topological polar surface area
37.3 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
22calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.95calc.
Formal charge
0calc.
Stereocentres
8calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCC2C(CCC3C4CCCC4CCC23)C1

O=C1CCC2C(CCC3C4CCCC4CCC23)C1

4 rings, 18 atoms.

338 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H351Suspected of causing cancer.
  • H360FDMay damage fertility. May damage the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Dromostanolone suppliers

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Dromostanolone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Antineoplastic.

Roles

  • agonist
  • anabolic agent
  • androgen
  • antineoplastic agent
  • hormone
  • molecular messenger
  • pharmaceutical
  • sex hormone

Functional uses

  • Pharmaceutical

Pharmacology

Dromostanolone is a synthetic anabolic steroid related to dihydrotestosterone that has antiestrogenic effects. Dromostanolone inhibits the growth of estrogen receptor-presenting breast cancers, its virilizing effects limit its clinical usefulness. (NCI04)

How it is made

Preparation: ... H.J. Ringold, G. Rosenkranz, US 3118915 (1964 to Sentex)

Regulatory status

Inventories, regulations and trade controls that list this substance

Controls

  • US DEA controlled substance or listed chemical

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dromostanolone is traded under.

HS 2937.29Indicative HS code

Steroidal hormones, their derivatives and structural analogues, other

World exports in 2024
$2.32B
+5.7% vs 2023, imports $2.41B
2019 to 2024
Top exporters
  1. Belgium25.3%
  2. United States24.9%
  3. China13.0%
Top importers
  1. Italy18.0%
  2. Canada13.0%
  3. Belgium12.2%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Dromostanolone is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dromostanolone, based on the data on this page

What is Dromostanolone?

Metholone is a 3-oxo-5alpha-steroid, a 17beta-hydroxy steroid and an anabolic androgenic steroid. It has a role as an antineoplastic agent and an anabolic agent.

What is the CAS number of Dromostanolone?

The CAS registry number of Dromostanolone is 58-19-5.

What is the molecular formula and weight of Dromostanolone?

The molecular formula of Dromostanolone is C20H32O2 and its molar mass is 304.47 g/mol.

What is Dromostanolone used for?

Antineoplastic.

Is Dromostanolone hazardous?

Dromostanolone carries the GHS signal word "Danger". Main hazards: suspected of causing cancer, may damage fertility. may damage the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Dromostanolone?

Dromostanolone is usually classified under HS code 293729 (Steroidal hormones, their derivatives and structural analogues, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dromostanolone?

Post a free request on CompoundList and suppliers of Dromostanolone will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Dromostanolone?

Suppliers quote Dromostanolone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dromostanolone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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