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Endostatin

Also known as Endostatins, YH 16, N-methyl-N-phenacylnitrous amide

CAS 187888-07-9Formula C9H10N2O2Molar mass 178.19 g/mol
Endostatin chemical structure, C9H10N2O2, CAS 187888-07-9
2D chemical structure

Key facts

What buyers check first

CAS number
187888-07-9
Formula
C9H10N2O2
Molar mass
178.19 g/mol
HS code
291439
Category
Aromatic building blocks

What is Endostatin?

Plain description, key identifiers and synonyms

Recombinant Human Endostatin is a recombinant human proteolytic fragment of the C-terminal end of type XVIII collagen. Endostatin induces microvascular endothelial cell apoptosis and inhibits endothelial proliferation and angiogenesis, which may result in a reduction in tumor burden. This agent also may decrease hepatic metastasis by inhibiting proinflammatory cytokines and vascular cell adhesion molecule (VCAM)-dependent cell attachment to the hepatic microvasculature. (NCI04)

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-methyl-N-phenacylnitrous amide
CAS number
187888-07-9 CAS number cross-checkedOther or deprecated CAS: 55984-52-6
Molecular formula
C9H10N2O2
InChIKey
AAFYOVPTFNNVDN-UHFFFAOYSA-N
InChI
InChI=1S/C9H10N2O2/c1-11(10-13)7-9(12)8-5-3-2-4-6-8/h2-6H,7H2,1H3
SMILES (canonical and isomeric)
CN(CC(=O)C1=CC=CC=C1)N=O

Synonyms

  • Endostatins
  • YH 16
  • N-methyl-N-phenacylnitrous amide
  • Ethanone, 2-(methylnitrosoamino)-1-phenyl-
  • 2-Oxo-2-phenylethylmethylnitrosamine
  • N-Methyl-N-(2-oxo-2-phenylethyl)nitrous amide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
178.19 g/molcalc.
Exact mass
178.0742 Dacalc.
LogP (octanol/water)
1.48calc.
Topological polar surface area
49.74 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
13calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.22calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Endostatin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

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  • China, BeijingUnclaimed profile
    EndostatinGrade, purity and minimum order on request
    Price on request
    View

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Where suppliers are based

1 supplier in 1 country

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Endostatin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Angiogenesis Inhibitors
  • Antineoplastic Agents

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Endostatin is traded under.

HS 2914.39Indicative HS code

Aromatic ketones without other oxygen function, other

World exports in 2024
$207M
−12.1% vs 2023, imports $191M
2019 to 2024
Top exporters
  1. China61.4%
  2. India * partner reported12.4%
  3. Italy7.6%
Top importers
  1. India * partner reported11.9%
  2. Germany9.9%
  3. United States8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Endostatin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Endostatin, based on the data on this page

What is Endostatin?

Recombinant Human Endostatin is a recombinant human proteolytic fragment of the C-terminal end of type XVIII collagen. Endostatin induces microvascular endothelial cell apoptosis and inhibits endothelial proliferation and angiogenesis, which may result in a reduction in tumor burden.

What is the CAS number of Endostatin?

The CAS registry number of Endostatin is 187888-07-9. Other or deprecated CAS numbers: 55984-52-6.

What is the molecular formula and weight of Endostatin?

The molecular formula of Endostatin is C9H10N2O2 and its molar mass is 178.19 g/mol.

What is Endostatin used for?

Known uses and roles of Endostatin include building blocks in research and laboratory, screening compounds in research and laboratory, angiogenesis inhibitors and antineoplastic agents.

Is Endostatin hazardous?

No GHS hazard classification for Endostatin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Endostatin?

Endostatin is usually classified under HS code 291439 (Aromatic ketones without other oxygen function, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Endostatin?

CompoundList lists 1 supplier of Endostatin in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Endostatin?

Suppliers quote Endostatin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Endostatin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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