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Insecticides and acaricides

Endosulfan

Also known as Benzoepin, Thiodan, Thionex

CAS 115-29-7Formula C9H6Cl6O3SMolar mass 406.93 g/molEC 204-079-4
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Hazardous to the environment Controlled, licensed buyers only
Request as a licensed buyer Safety data
Endosulfan chemical structure, C9H6Cl6O3S, CAS 115-29-7
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Brown crystals [Note: Technical product is a tan, waxy, isomer mixture]
Melting point
106 °C
Boiling point
106 °C
Density
1.7 g/cm³
Solubility
Solubility at 22 °C and a pH 7.2 in tap water, alpha-Endosulfan: 0.15 mg/l.
HS code
292030
Category
Insecticides and acaricides
UN number
UN 2761

What is Endosulfan?

Plain description, key identifiers and synonyms

Endosulfan is a cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10. It has a role as an acaricide, an agrochemical, a GABA-gated chloride channel antagonist and a persistent organic pollutant. It is a cyclodiene organochlorine insecticide and a cyclic sulfite ester.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,9,10,11,12,12-hexachloro-4,6-dioxa-5λ4-thiatricyclo[7.2.1.02,8]dodec-10-ene 5-oxide
CAS number
115-29-7 CAS number cross-checked
EC number
204-079-4
Molecular formula
C9H6Cl6O3S
UNII
OKA6A6ZD4K
InChIKey
RDYMFSUJUZBWLH-UHFFFAOYSA-N
InChI
InChI=1S/C9H6Cl6O3S/c10-5-6(11)8(13)4-2-18-19(16)17-1-3(4)7(5,12)9(8,14)15/h3-4H,1-2H2
SMILES (canonical and isomeric)
C1C2C(COS(=O)O1)C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl

Synonyms

  • Benzoepin
  • Thiodan
  • Thionex
  • Chlorthiepin
  • Thiosulfan
  • Malix
  • Devisulphan
  • Endosulphan
  • Insectophene
  • Rasayansulfan
  • Endocel
  • Endotaf
  • Beosit
  • Hildan
  • Sialan
  • Thifor
  • Thimul
  • Tionex
  • Tiovel
  • Crisulfan
  • Thiodan 35
  • Phaser
  • Kop-thiodan
  • Thiotox (insecticide)
  • Thiosulfan tionel
Show all 39 synonyms
  • Niagara 5,462
  • Thiodan 4EC
  • PFF Thiodan 4E
  • Endosulfan 35 EC
  • Endosol
  • Thiodan 50 WP
  • Thiodan Dust Insecticide
  • Thiodan 4EC Insecticide
  • OMS 570
  • Thiodan 50 WP Insecticide
  • FMC 5462
  • BIO 5,462
  • HOE 2,671
  • Thiodan 4E Insecticide Liquid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Brown crystals [Note: Technical product is a tan, waxy, isomer mixture]exp.
Odour
Similar to terpene.exp.
Melting point
106 °Cexp.
Boiling point
106 °Cexp.
Density
1.7 g/cm³exp.
Solubility
Solubility at 22 °C and a pH 7.2 in tap water, alpha-Endosulfan: 0.15 mg/l.exp.
Vapour pressure
VP: 6.2 × 10⁻⁶ mm Hg at 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
406.93 g/molcalc.
Exact mass
403.8169 Dacalc.
LogP (octanol/water)
3.69calc.
Topological polar surface area
35.53 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
0calc.
Heavy atoms
19calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.78calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=S1OCC2C3C=CC(C3)C2CO1

O=S1OCC2C3C=CC(C3)C2CO1

3 rings, 13 atoms.

4 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H300Fatal if swallowed.
  • H312Harmful in contact with skin.
  • H330Fatal if inhaled.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (20)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2761
Transport hazard class
6.1
Packing group
II

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Endosulfan suppliers

Controlled substance, listings of documented suppliers only, in the documented ranking

Persistent organic pollutant

Endosulfan is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.

Licensed buyers only, every enquiry is reviewed by our compliance team.

Reference: Stockholm Convention on Persistent Organic Pollutants, HS 2022 subheading 2920.30 (endosulfan)

Our policy on controlled substances
No documented supplier lists it yet

Licensed buyers can post a request for Endosulfan with their licence. Our compliance team reviews it before suppliers see it.

Request as a licensed buyer

Endosulfan price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Non-systemic insecticide and acaricide.

Insecticide used to control the Colorado potato beetle, flea beetle, cabbageworm, peach tree borer, and the tarnished plant bug.

Endosulfan is a broad spectrum contact insecticide and acaricide registered for use on a wide variety of vegetables, fruits, cereal grains, and cotton, as well as ornamental shrubs, trees, vines, and ornamentals for use in commercial agricultural settings.

For use on cereal, citrus, coffee, deciduous, fiber and forage crops, forest, nuts, oil crops, ornamentals, rice, small fruits, tea, tobacco, vegetables. Controls tsetse fly.

Use classes: Pesticides, Insecticides, Acaricides, Insecticides.

Pharmacological actions

  • Insecticides

Roles

  • GABA-gated chloride channel antagonist
  • acaricide
  • agrochemical
  • antagonist
  • biophysical role
  • environmental contaminant
  • membrane transport modulator
  • persistent organic pollutant
  • pesticide

Functional uses

  • Biocide

How it is made

Endosulfan is produced by reaction of 1,2,3,4,7,7-hexachloro-5,6-dihydroxymethylbicylo[2,2,1]-hept-5-ene, obtained by condensation of cis-1,4-dihydroxybut-2-ene with hexachlorocyclopentadiene, with thionyl chloride.

Prepared by reaction of hexachlorocyclopentadiene with cis-butene-1,4-diol to form bicyclic dialcohol followed by esterification and cyclization with SOCl2.

Regulatory status

Inventories, regulations and trade controls that list this substance

Persistent organic pollutant

Endosulfan is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.

Licensed buyers only, every enquiry is reviewed by our compliance team.

Reference: Stockholm Convention on Persistent Organic Pollutants, HS 2022 subheading 2920.30 (endosulfan)

Our policy on controlled substances

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 602-052-00-5

Agriculture and environment

  • Stockholm Convention persistent organic pollutant

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Endosulfan is traded under.

HS 2920.30Exact HS code

Endosulfan (ISO)

World exports in 2024
$49.2K
−72.3% vs 2023, imports $89.7K
2019 to 2024
Top exporters
  1. United States42.8%
  2. Germany22.8%
  3. Spain21.1%
Top importers
  1. Italy57.2%
  2. Portugal20.4%
  3. Switzerland * partner reported6.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Endosulfan is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Endosulfan, based on the data on this page

What is Endosulfan?

Endosulfan is a cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10. It has a role as an acaricide, an agrochemical, a GABA-gated chloride channel antagonist and a persistent organic pollutant.

What is the CAS number of Endosulfan?

The CAS registry number of Endosulfan is 115-29-7.

What is the molecular formula and weight of Endosulfan?

The molecular formula of Endosulfan is C9H6Cl6O3S and its molar mass is 406.93 g/mol.

What is Endosulfan used for?

Non-systemic insecticide and acaricide. Insecticide used to control the Colorado potato beetle, flea beetle, cabbageworm, peach tree borer, and the tarnished plant bug.

Is Endosulfan hazardous?

Endosulfan carries the GHS signal word "Danger". Main hazards: fatal if swallowed, harmful in contact with skin, fatal if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Endosulfan?

Endosulfan is usually classified under HS code 292030 (Endosulfan (ISO)). This is indicative, confirm it with your customs broker before shipping.

Can I buy Endosulfan on CompoundList?

Endosulfan is a controlled substance. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed by our compliance team before suppliers see it.

Guides for buyers

Practical guides that help when you source, ship or handle Endosulfan

Request as a licensed buyer

Upload your licence with the request. Our compliance team reviews it before the documented suppliers see it.
Request as a licensed buyer
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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