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Alkaloids

Etofylline

Also known as 7-(2-Hydroxyethyl)theophylline, Aethophyllinum, Frekaphyllin

CAS 519-37-9Formula C9H12N4O3Molar mass 224.22 g/molEC 208-269-8
GHS signal word: Warning. Pictograms: Harmful or irritant 16 suppliers listed
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Etofylline chemical structure, C9H12N4O3, CAS 519-37-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
519-37-9
Formula
C9H12N4O3
Molar mass
224.22 g/mol
EC number
208-269-8
HS code
293959
Category
Alkaloids

What is Etofylline?

Plain description, key identifiers and synonyms

7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione is an oxopurine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione
CAS number
519-37-9 CAS number cross-checked
EC number
208-269-8
Molecular formula
C9H12N4O3
UNII
L164909TBI
MDL number
MFCD00055055
InChIKey
NWPRCRWQMGIBOT-UHFFFAOYSA-N
InChI
InChI=1S/C9H12N4O3/c1-11-7-6(8(15)12(2)9(11)16)13(3-4-14)5-10-7/h5,14H,3-4H2,1-2H3
SMILES (canonical and isomeric)
CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCO

Synonyms

  • 7-(2-Hydroxyethyl)theophylline
  • Aethophyllinum
  • Frekaphyllin
  • Soluphylline
  • Phyllocormin N
  • Oxyethyltheophylline
  • Oxyphyllin
  • Etofilina
  • Etofyllinum
  • Etofillina
  • Hydroxyethyltheophylline
  • 3,7-Dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-1H-purine-2,6-dione
  • 7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione
  • Doxophylline metabolite m4
  • etophylline
  • etophyllin
  • Cordalin
  • Ascorphylline
  • Dilaphyllin
  • Oxyphylline
  • Oxytheonyl
  • Bio-phylline
  • Corophyllin-N
  • Sklerodormal
  • Oxphylline (amido)
Show all 38 synonyms
  • 1,3-Dimethyl-7-(2-hydroxyethyl)xanthine
  • 7-(Hydroxyethyl)theophylline
  • 7-hydroxyethyltheophylline
  • 7-Theophyllineethanol
  • 7-(2-Hydroxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
  • 7-(2-Hydroxyethyl)-1,3-dimethylxanthine
  • Hydroxyethyl theophylline
  • Theophylline, 7-(2-hydroxyethyl)-
  • Oxyaethyltheophyllin
  • B-hydroxyethyltheophylline
  • 7-(2-Hydroxyethyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
  • beta-Hydroxyethyl theophylline
  • 1H-Purine-2,6-dione, 3,7-dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
224.22 g/molcalc.
Exact mass
224.0909 Dacalc.
LogP (octanol/water)
-1.57calc.
Topological polar surface area
82.05 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
16calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.44calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1[nH]c(=O)c2[nH]cnc2[nH]1

O=c1[nH]c(=O)c2[nH]cnc2[nH]1

2 rings, 11 atoms, the Xanthine ring system.

1,880 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Etofylline suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 16 suppliers
16 of 16 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

16 suppliers in 5 countries

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Etofylline price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Bronchodilator Agents

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Etofylline is traded under.

HS 2939.59Indicative HS code

Theophylline and aminophylline (theophylline-ethylenediamine) and their derivatives…

World exports in 2024
$56M
+6.9% vs 2023, imports $62.2M
2019 to 2024
Top exporters
  1. India * partner reported46.2%
  2. China22.9%
  3. Italy14.5%
Top importers
  1. United States10.4%
  2. Italy9.2%
  3. South Korea7.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Etofylline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Etofylline, based on the data on this page

What is Etofylline?

7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione is an oxopurine.

What is the CAS number of Etofylline?

The CAS registry number of Etofylline is 519-37-9.

What is the molecular formula and weight of Etofylline?

The molecular formula of Etofylline is C9H12N4O3 and its molar mass is 224.22 g/mol.

What is Etofylline used for?

Known uses and roles of Etofylline include bronchodilator agents.

Is Etofylline hazardous?

Etofylline carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Etofylline?

Etofylline is usually classified under HS code 293959 (Theophylline and aminophylline (theophylline-ethylenediamine) and their derivatives…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Etofylline?

CompoundList lists 16 suppliers of Etofylline in United States, China, Czech Republic, Germany and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Etofylline in India?

1 supplier in India list Etofylline on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Etofylline?

Suppliers quote Etofylline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Etofylline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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