CompoundList
Sign in
Central nervous system drugs

Etomidate

Also known as Hypnomidate, Amidate, (+)-Etomidate

CAS 33125-97-2Formula C14H16N2O2Molar mass 244.29 g/molEC 251-385-9
GHS signal word: Warning. Pictograms: Harmful or irritant, Hazardous to the environment 67 suppliers listed Drug substance
Get quotes Compare 67 suppliers
Etomidate chemical structure, C14H16N2O2, CAS 33125-97-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
33125-97-2
Formula
C14H16N2O2
Molar mass
244.29 g/mol
EC number
251-385-9
HS code
293329
Category
Central nervous system drugs

What is Etomidate?

Plain description, key identifiers and synonyms

Etomidate is the ethyl ester of 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. It is an intravenous general anaesthetic with no analgesic activity. It has a role as a sedative and an intravenous anaesthetic. It is an ethyl ester and a member of imidazoles. It is functionally related to a 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
ethyl 3-[(1R)-1-phenylethyl]imidazole-4-carboxylate
CAS number
33125-97-2 CAS number cross-checked
EC number
251-385-9
Molecular formula
C14H16N2O2
UNII
Z22628B598
MDL number
MFCD00869295
InChIKey
NPUKDXXFDDZOKR-LLVKDONJSA-N
InChI
InChI=1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1
Canonical SMILES
CCOC(=O)c1cncn1C(C)c1ccccc1
Isomeric SMILES
CCOC(=O)C1=CN=CN1[C@H](C)C2=CC=CC=C2

Synonyms

  • Hypnomidate
  • Amidate
  • (+)-Etomidate
  • D-Etomidate
  • Etomidato
  • Etomidatum
  • ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate
  • (+)-Ethyl 1-(alpha-methylbenzyl)imidazole-5-carboxylate
  • ethyl 3-[(1R)-1-phenylethyl]imidazole-4-carboxylate
  • R-(+)-Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate
  • (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester
  • (R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester
  • 1H-Imidazole-5-carboxylic acid, 1-[(1R)-1-phenylethyl]-, ethyl ester
  • 3-((R)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic acid ethyl ester
  • 1H-Imidazole-5-carboxylic acid, 1-((1R)-1-phenylethyl)-, ethyl ester
  • Ethomidate
  • Imidazole-5-carboxylic acid, 1-(alpha-methylbenzyl)-, ethyl ester, (R)-(+)-
  • ethyl 3-((1R)-1-phenylethyl)imidazole-4-carboxylate
  • ethyl 1-((1R)-1-phenylethyl)-1H-imidazole-5-carboxylate
  • Etomidate Injection
  • Amidate(tm) etomidate
  • ETOMIDATE injection, solution
  • (R)-Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate
  • Radenarcon
  • Amidate (pharmaceutical)
Show all 36 synonyms
  • ethyl (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylate
  • 1H-Imidazole-5-carboxylic acid, 1-(1-phenylethyl)-, ethyl ester, (R)-
  • (d)-Etomidate
  • Etomidic acid
  • (R)-(+)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic Acid Ethyl Ester
  • 1H-Imidazole-5-carboxylic acid, 1-(1-phenylethyl)-, ethyl ester, (+)-
  • Amidate (TN)
  • 1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester
  • Hypnomidate,
  • Amidate,
  • Etomidate CRS

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
244.29 g/molcalc.
Exact mass
244.1212 Dacalc.
LogP (octanol/water)
2.67calc.
Topological polar surface area
44.12 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
18calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.29calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Cn2ccnc2)cc1

c1ccc(Cn2ccnc2)cc1

2 rings, 12 atoms, the 1-Benzylimidazole ring system.

1,214 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H332Harmful if inhaled.
  • H400Very toxic to aquatic life.
Precautionary statements (11)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P330Rinse mouth.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Etomidate suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 67 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

67 suppliers in 16 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Etomidate price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Anesthetics, Intravenous
  • Hypnotics and Sedatives

Roles

  • anaesthetic
  • antihypertensive agent
  • cardiovascular drug
  • central nervous system depressant
  • central nervous system drug
  • general anaesthetic
  • intravenous anaesthetic
  • pharmaceutical
  • sedative

Pharmacology

Etomidate is a General Anesthetic. The physiologic effect of etomidate is by means of General Anesthesia.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Etomidate is traded under.

HS 2933.29Indicative HS code

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…

World exports in 2024
$1.43B
−7.6% vs 2023, imports $1.47B
2019 to 2024
Top exporters
  1. China28.1%
  2. France * partner reported12.7%
  3. India * partner reported10.3%
Top importers
  1. United Kingdom13.0%
  2. United States7.9%
  3. China6.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Etomidate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Etomidate, based on the data on this page

What is Etomidate?

Etomidate is the ethyl ester of 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. It is an intravenous general anaesthetic with no analgesic activity. It has a role as a sedative and an intravenous anaesthetic. It is an ethyl ester and a member of imidazoles.

What is the CAS number of Etomidate?

The CAS registry number of Etomidate is 33125-97-2.

What is the molecular formula and weight of Etomidate?

The molecular formula of Etomidate is C14H16N2O2 and its molar mass is 244.29 g/mol.

What is Etomidate used for?

Known uses and roles of Etomidate include cns agents in pharmaceuticals, anaesthetic, antihypertensive agent, cardiovascular drug, central nervous system depressant and 7 more.

Is Etomidate hazardous?

Etomidate carries the GHS signal word "Warning". Main hazards: harmful if swallowed, harmful if inhaled, very toxic to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Etomidate?

Etomidate is usually classified under HS code 293329 (Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Etomidate?

CompoundList lists 67 suppliers of Etomidate in United States, China, India, Germany and 12 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Etomidate in India?

8 suppliers in India list Etomidate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Etomidate?

Suppliers quote Etomidate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Etomidate

Get quotes for Etomidate

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Etomidate
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Etomidate with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/etomidate-33125-97-2" title="Etomidate structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Central nervous system drugs or HS code 293329

67 suppliers
Free quotes, contact stays private
Get quotes