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Insecticides and acaricides

Flufenoxuron

Also known as Cascade, N-(((4-(2-chloro-4-(trifluoromethyl)phenoxy)-2-fluorophenyl)amino)carbonyl)-2,6-difluorobenzamide, N-[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]carbamoyl]-2,6-difluorobenzamide

CAS 101463-69-8Formula C21H11ClF6N2O3Molar mass 488.77 g/molEC 417-680-3
GHS signal word: Warning. Pictograms: Hazardous to the environment 12 suppliers listed
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Flufenoxuron chemical structure, C21H11ClF6N2O3, CAS 101463-69-8
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless crystals
Melting point
169 to 172
Density
Relative density = 1.57 g/mL
Solubility
In water, 3.8 ug/L (deionized water)
HS code
292519
Category
Insecticides and acaricides
Illustrative photo, colourless crystals in small glass vials on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Flufenoxuron?

Plain description, key identifiers and synonyms

Flufenoxuron is a benzoylurea insecticide, a difluorobenzene, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes. It has a role as a mite growth regulator. It is functionally related to a diphenyl ether.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]carbamoyl]-2,6-difluorobenzamide
CAS number
101463-69-8 CAS number cross-checked
EC number
417-680-3
Molecular formula
C21H11ClF6N2O3
UNII
OD068OSS0N
InChIKey
RYLHNOVXKPXDIP-UHFFFAOYSA-N
InChI
InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)
SMILES (canonical and isomeric)
C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=C(C=C(C=C2)OC3=C(C=C(C=C3)C(F)(F)F)Cl)F)F

Synonyms

  • Cascade
  • N-(((4-(2-chloro-4-(trifluoromethyl)phenoxy)-2-fluorophenyl)amino)carbonyl)-2,6-difluorobenzamide
  • N-[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]carbamoyl]-2,6-difluorobenzamide
  • N-((4-(2-Chloro-4-(trifluoromethyl)phenoxy)-2-fluorophenyl)carbamoyl)-2,6-difluorobenzamide
  • DPX EY-059
  • N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide
  • 1-(4-(2-chloro-4-(trifluromethyl)phenoxy)-2-fluorophenyl)-3-(2,6-difluorobenzoyl)urea
  • 1-(4-(2-Chloro-alpha,alpha,alpha-trifluoro-p-tolyloxy)-2-fluorophenyl)-3-(2,6-difluorobenzoyl)urea
  • Benzamide, N-[[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]amino]carbonyl]-2,6-difluoro-
  • Cascade, WL 115110
  • Benzamide, N-(((4-(2-chloro-4-(trifluoromethyl)phenoxy)-2-fluorophenyl)amino)carbonyl)-2,6-difluoro-
  • WL 115110
  • Flufenoxuron (Standard)
  • Rylhnovxkpxdip-uhfffaoysa-
  • Flufenoxuron 1000 |Ig/mL in Acetone
  • Flufenoxuron 10 |Ig/mL in Cyclohexane
  • Flufenoxuron 1000 microg/mL in Acetone
  • Flufenoxuron 10 microg/mL in Cyclohexane
  • Flufenoxuron, PESTANAL(R), analytical standard
  • 1-[4-(2-chloro-4-trifluoromethylphenoxy)-2-fluorophenyl]-3-(2,6-difluorobenzoyl)urea
  • N-[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]carbamoyl]-2,6-difluo
  • 1-(4-(2-Cloro-alpha,alpha,alpha-P-trifluorotolyloxy)-2-fluorophenyl)-3-(2,6-difluorobenzolyl)urea
  • 1-[4-(5-chloro-alpha,alpha,alpha-trifluoro-p-tolyloxy)-2-fluorophenyl]-3-(2,6-difluorobenzoyl)urea

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless crystalsexp.
Odour
Odorlessexp.
Melting point
169 to 172exp.
Density
Relative density = 1.57 g/mLexp.
Solubility
In water, 3.8 ug/L (deionized water)exp.
Vapour pressure
6.52 × 10⁻⁹ mPa /SRC: 4.89 × 10⁻¹⁴ mm Hg/ at 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
488.77 g/molcalc.
Exact mass
488.0362 Dacalc.
LogP (octanol/water)
6.53calc.
Topological polar surface area
67.43 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
33calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.05calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NC(=O)c1ccccc1)Nc1ccc(Oc2ccccc2)cc1

O=C(NC(=O)c1ccccc1)Nc1ccc(Oc2ccccc2)cc1

3 rings, 25 atoms.

8 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H362May cause harm to breast-fed children.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (9)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P263Avoid contact during pregnancy and while nursing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P318If exposed or concerned, get medical advice.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Flufenoxuron suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 12 suppliers
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Where suppliers are based

12 suppliers in 4 countries

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Flufenoxuron price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Insecticide/acaricide.

There are currently no food/feed uses or tolerances for flufenoxuron in the U.S. BASF Corporation is supporting the use of flufenoxuron on apples, grapes and oranges grown for export to the U.S. in selected European and South American countries.

Use classes: Acaricides, Insecticides.

Roles

  • acaricide
  • growth regulator
  • mite growth regulator
  • pesticide

Functional uses

  • Biocide

How it is made

Flufenoxuron is produced by reaction of 2-fluoro-4-hydroxyaniline in KOH-containing dimethyl sulfoxide with 3,4-dichlorotrifluoromethyltoluene to give the corresponding phenoxyaniline, which is treated with 2,6-difluorophenyl isocyanate.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 616-206-00-4

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Flufenoxuron is traded under.

HS 2925.19Indicative HS code

Imides and their derivatives, salts thereof, other

World exports in 2024
$295M
+11.7% vs 2023, imports $348M
2019 to 2024
Top exporters
  1. China29.7%
  2. Japan22.7%
  3. United Kingdom10.0%
Top importers
  1. United States12.7%
  2. Brazil12.6%
  3. China10.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Flufenoxuron is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Flufenoxuron, based on the data on this page

What is Flufenoxuron?

Flufenoxuron is a benzoylurea insecticide, a difluorobenzene, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes. It has a role as a mite growth regulator. It is functionally related to a diphenyl ether.

What is the CAS number of Flufenoxuron?

The CAS registry number of Flufenoxuron is 101463-69-8.

What is the molecular formula and weight of Flufenoxuron?

The molecular formula of Flufenoxuron is C21H11ClF6N2O3 and its molar mass is 488.77 g/mol.

What is Flufenoxuron used for?

Insecticide/acaricide. There are currently no food/feed uses or tolerances for flufenoxuron in the U.S. BASF Corporation is supporting the use of flufenoxuron on apples, grapes and oranges grown for export to the U.S. in selected European and South American countries. Use classes: Acaricides, Insecticides.

Is Flufenoxuron hazardous?

Flufenoxuron carries the GHS signal word "Warning". Main hazards: may cause harm to breast-fed children, very toxic to aquatic life, very toxic to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Flufenoxuron?

Flufenoxuron is usually classified under HS code 292519 (Imides and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Flufenoxuron?

CompoundList lists 12 suppliers of Flufenoxuron in China, Brazil, France and United Kingdom. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Flufenoxuron?

Suppliers quote Flufenoxuron on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Flufenoxuron

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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