Formothion
Also known as Anthio, Toprose, Aflix
Key facts
What buyers check first
- Appearance
- Yellowish liquid
- Melting point
- 25 to 26
- Boiling point
- Decomposes on distillation
- Density
- 1.361 at 20 °C
- Solubility
- In water, 2.6 × 10⁺³ mg/L at 24 °C
- HS code
- 293090
- Category
- Insecticides and acaricides
- UN number
- UN 3018
What is Formothion?
Plain description, key identifiers and synonyms
Formothion is a dicarboximide.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2-dimethoxyphosphinothioylsulfanyl-N-formyl-N-methylacetamide
- CAS number
- 2540-82-1 CAS number cross-checked
- EC number
- 219-818-6
- Molecular formula
- C6H12NO4PS2
- UNII
- 7O9EWV477R
- MDL number
- MFCD00055528
- InChIKey
- AIKKULXCBHRFOS-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H12NO4PS2/c1-7(5-8)6(9)4-14-12(13,10-2)11-3/h5H,4H2,1-3H3
- SMILES (canonical and isomeric)
- CN(C=O)C(=O)CSP(=S)(OC)OC
Synonyms
- Anthio
- Toprose
- Aflix
- Antio
- Anthio 25
- Spencer S-6900
- Sandoz S-6900
- Formothion 25 EC
- Afliz
- Afliz [Sandoz]
- SAN 244 I
- SAN 6913 I
- SAN 7107 I
- VEL 4284
- ENT 27,257
- CP 53926
- S-(N-Formyl-N-methylcarbamoylmethyl) O,O-dimethyl phosphorodithioate
- Phosphorodithioic acid, S-(2-(formylmethylamino)-2-oxoethyl) O,O-dimethyl ester
- O,O-Dimethyl dithiophosphorylacetic acid N-methyl-N-formylamide
- O,O-Dimethyl S-(N-methyl-N-formylcarbamoylmethyl)phosphorodithioate
- S-(Formyl(methyl)carbamoylmethyl) O,O-dimethyl phosphorodithioate
- O,O-Dimethyl S-(N-formyl-N-methylcarbamoylmethyl) phosphorodithioate
- S-(2-(Formylmethylamino)-2-oxoethyl) O,O-dimethyl phosphorodithioate
- S-(2-(Formylmethylamino)-2-oxoethyl) O,O-dimethylphosphorodithioate
- S-(N-Formyl-N-methylcarbamoylmethyl) dimethyl phosphorothiolothionate
Show all 38 synonymsShow fewer synonyms
- O,O-Dimethyl phosphorodithioate N-formyl-2-mercapto-N-methylacetamide S-ester
- Acetamide, N-formyl-2-mercapto-N-methyl-, S-ester with O,O-dimethyl phosphorodithioate
- Phosphorodithioic acid, O,O-dimethyl ester, N-formyl-2-mercapto-N-methylacetamide S-ester
- Afliz (Sandoz)
- Phosphorodithioic acid S-(2-(formylmethylamino)-2-oxoethyl) O,O-dimethyl ester
- O,O-Dimethyl-S-(3-methyl-2,4-dioxo-3-aza-butyl)-dithiofosfaat
- O,O-Dimetil-S-(N-formil-N-metil-carbamoil-metil)-ditiofosfato
- O,O-Dimethyl-S-(3-methyl-2,4-dioxo-3-aza-butyl)-dithiophosphat
- O,O-Dimethyl-s-(N-methyl-N-formyl-carbamoylmethyl)-dithiophosphat
- Phosphorodithioic acid, S-[2-(formylmethylamino)-2-oxoethyl] O,O-dimethyl ester
- Phosphorodithioic acid, O,O-dimethyl ester, S-ester with N-formyl-2-mercapto-N-methylacetamide
- 2-dimethoxyphosphinothioylsulfanyl-N-formyl-N-methylacetamide
- N-Formyl-N-methylcarbamoylmethyl O,O-dimethyl phosphorodithioate
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Yellowish liquidexp.Measured value |
|---|---|
| Odour | Odorlessexp.Measured value |
| Melting point | 25 to 26exp.Measured value |
| Boiling point | Decomposes on distillationexp.Measured value |
| Density | 1.361 at 20 °Cexp.Measured value |
| Solubility | In water, 2.6 × 10⁺³ mg/L at 24 °Cexp.Measured value |
| Vapour pressure | 8.48 × 10⁻⁷ mm Hg at 30 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 257.27 g/molcalc.Computed value |
|---|---|
| Exact mass | 256.9945 Dacalc.Computed value |
| LogP (octanol/water) | 0.85calc.Computed value |
| Topological polar surface area | 55.84 Ųcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 6calc.Computed value |
| Rotatable bonds | 6calc.Computed value |
| Heavy atoms | 14calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.67calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H312Harmful in contact with skin.
Precautionary statements (10)
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P302 + P352If on skin: Wash with plenty of water.
- P317Get medical help.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P501Dispose of contents and container in accordance with local regulations.
- UN number
- UN 3018
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
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Formothion price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
It is a contact and systemic insecticide and acaricide, effective at 250-500 g ai/ha or at 1.0-1.5 g ai/L, against a wide range of sucking and mining insects such as chewing insects (Cydia pominella and Epilachna beetles) and spider mites.
May be used against spider mites (non-op (non-organophosphate) resistant strains only), aphids (non-op resistant strains only), psyllids, mealy bugs, armored scales, whiteflies, jassids, thrips, leaf miners, ermine moths, sawflies, fruit flies, olive fly, asparagus fly, mangold fly.
Acaricide, systemic insecticide.
Industries and functions
Pharmacological actions
- Insecticides
Pharmacology
Formothion is a synthetic dicarboximide compound and organophosphate acetylcholinesterase inhibitor that is used as a pesticide. It is characterized as a viscous yellow oily liquid or crystalline solid, and exposure occurs by inhalation, ingestion, or contact.
How it is made
Made by the reaction of 2-chloro-N-formyl-N-methylacetamide with ammonium O,O-dimethyl phosphorodithioate.
Chloroacetyl chloride + N-methylformamide + O,O-dimethyl dithiophosphoric acid (amide formation/ dehydrochlorination).
Formothion is produced by reaction of the sodium salt of O,O-dimethyldithiophosphoric acid with N-methyl N-formyl carbamoylmethyl chloride.
Regulatory status
Inventories, regulations and trade controls that list this substance
Europe
- EU harmonised classification (CLP Annex VI)Index no: 015-057-00-7
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Formothion is traded under.
Organo-sulphur compounds, other
- China40.7%
- United States10.9%
- Japan9.3%
- United States13.3%
- Brazil12.6%
- China6.6%
The HS code shown for Formothion is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Similar structures
Nearest neighbours by Morgan fingerprint Tanimoto similarity
Frequently asked questions
Quick answers about Formothion, based on the data on this page
What is Formothion?
What is the CAS number of Formothion?
What is the molecular formula and weight of Formothion?
What is Formothion used for?
Is Formothion hazardous?
What is the HS code of Formothion?
Where can I buy Formothion?
What is the price of Formothion?
Guides for buyers
Practical guides that help when you source, ship or handle Formothion
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, Trade and logisticsShipping dangerous goods: UN numbers, classes and packing groupsHow the UN dangerous goods system works for chemicals, from the nine classes and UN numbers to packing groups, UN packaging marks, labels, documents and segregation.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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