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Pharmaceuticals and APIs

Gentamicin

Also known as Uromycine, Cidomycin, Gentamycinum

CAS 1403-66-3Formula C21H43N5O7Molar mass 477.60 g/molEC 215-765-8
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard, Hazardous to the environment 64 suppliers listed Drug substance
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Gentamicin chemical structure, C21H43N5O7, CAS 1403-66-3
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White amorphous powder
Melting point
102 to 108
Solubility
Freely soluble in water
HS code
294190
Category
Pharmaceuticals and APIs
Illustrative photo, a white jumbo bulk bag of powder in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Gentamicin?

Plain description, key identifiers and synonyms

Gentamicin is a broad-spectrum aminoglycoside antibiotic produced by fermentation of Micromonospora purpurea or M. echinospora. Gentamicin is an antibiotic complex consisting of four major (C1, C1a, C2, and C2a) and several minor components. This agent irreversibly binds to the bacterial 30S ribosomal subunit. Specifically, this antibiotic is lodged between 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex, misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.

Gentamicin is a pharmaceutic extract of Micromonospora purpurea.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
CAS number
1403-66-3 CAS number cross-checkedOther or deprecated CAS: 1294497-75-8
EC number
215-765-8
Molecular formula
C21H43N5O7
UNII
T6Z9V48IKG
MDL number
MFCD00072030
InChIKey
CEAZRRDELHUEMR-UHFFFAOYSA-N
InChI
InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3
SMILES (canonical and isomeric)
CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC

Synonyms

  • Uromycine
  • Cidomycin
  • Gentamycinum
  • Gentamicina
  • Gentamicine
  • Gentamycin-creme
  • Gentamycin
  • Oksitselanim
  • Lyramycin
  • Septigen
  • Gentamycins
  • 2-[4,6-diamino-3-[3-amino-6-(1-methylaminoethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-methylaminooxane-3,5-diol
  • Garamicin
  • Gentamycin Complex
  • 2-(4,6-diamino-3-(3-amino-6-(1-methylaminoethyl)oxan-2-yl)oxy-2-hydroxycyclohexyl)oxy-5-methyl-4-methylaminooxane-3,5-diol
  • Garamycin
  • Gentamicins
  • Gentacycol
  • 2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
  • Gentamicinum
  • Refobacin TM
  • Centicin
  • Gentamicin (BAN)
  • 2-{[4,6-diamino-3-({3-amino-6-[1-(methylamino)ethyl]oxan-2-yl}oxy)-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White amorphous powderexp.
Melting point
102 to 108exp.
Solubility
Freely soluble in waterexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
477.60 g/molcalc.
Exact mass
477.3162 Dacalc.
LogP (octanol/water)
-3.33calc.
Topological polar surface area
199.7 Ųcalc.
Hydrogen bond donors
8calc.
Hydrogen bond acceptors
12calc.
Rotatable bonds
7calc.
Heavy atoms
33calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
13calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCC(OC2CCCC(OC3CCCCO3)C2)OC1

C1CCC(OC2CCCC(OC3CCCCO3)C2)OC1

3 rings, 20 atoms.

211 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H317May cause an allergic skin reaction.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H360May damage fertility or the unborn child.
  • H360DMay damage the unborn child.
  • H372Causes damage to organs through prolonged or repeated exposure.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (23)
  • P203Obtain, read and follow all safety instructions before use.
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403Store in a well-ventilated place.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Gentamicin suppliers

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All 64 suppliers
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Where suppliers are based

64 suppliers in 21 countries

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Gentamicin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Veterinary medication:.

Anti-Bacterial Agents, Protein Synthesis Inhibitors.

Use classes: Pharmaceuticals, Animal Drugs.

Pharmacology

Gentamicin is an Aminoglycoside Antibacterial.

How it is made

Antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora and variants thereof.

Recovered from a fermentation broth produced when submerged cultures of two subspecies of Micromonospora purpurea are grown in a yeast extract-cerelose medium.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Gentamicin is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Gentamicin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Gentamicin, based on the data on this page

What is Gentamicin?

Gentamicin is a broad-spectrum aminoglycoside antibiotic produced by fermentation of Micromonospora purpurea or M. echinospora. Gentamicin is an antibiotic complex consisting of four major (C1, C1a, C2, and C2a) and several minor components. This agent irreversibly binds to the bacterial 30S ribosomal subunit.

What is the CAS number of Gentamicin?

The CAS registry number of Gentamicin is 1403-66-3. Other or deprecated CAS numbers: 1294497-75-8.

What is the molecular formula and weight of Gentamicin?

The molecular formula of Gentamicin is C21H43N5O7 and its molar mass is 477.60 g/mol.

What is Gentamicin used for?

Veterinary medication:. Anti-Bacterial Agents, Protein Synthesis Inhibitors. Use classes: Pharmaceuticals, Animal Drugs.

Is Gentamicin hazardous?

Gentamicin carries the GHS signal word "Danger". Main hazards: may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled, may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Gentamicin?

Gentamicin is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Gentamicin?

CompoundList lists 64 suppliers of Gentamicin in United States, China, India, Germany and 17 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Gentamicin in India?

11 suppliers in India list Gentamicin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Gentamicin?

Suppliers quote Gentamicin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Gentamicin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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