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Skin conditioning agents and actives

Glucuronolactone

Also known as D-Glucurono-6,3-lactone, D-Glucuronolactone, Glucurolactone

CAS 32449-92-6Formula C6H8O6Molar mass 176.12 g/molEC 251-053-3
GHS signal word: Warning. Pictograms: Harmful or irritant 40 suppliers listed
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Glucuronolactone chemical structure, C6H8O6, CAS 32449-92-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
32449-92-6
Formula
C6H8O6
Molar mass
176.12 g/mol
Physical form
Liquid
HS code
293220
Category
Skin conditioning agents and actives
Illustrative photo, closed blue steel drums of liquid in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Glucuronolactone?

Plain description, key identifiers and synonyms

D-glucurono-6,3-lactone is a glucuronolactone. It has a role as a mouse metabolite and a human metabolite. It is functionally related to a D-glucuronic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R)-2-[(2S,3R,4S)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetaldehyde
CAS number
32449-92-6Other or deprecated CAS: 63-29-6, 6814-06-8
EC number
251-053-3
Molecular formula
C6H8O6
UNII
XE4Y3016M9
MDL number
MFCD00135622
INCI name
GLUCURONOLACTONE
InChIKey
UYUXSRADSPPKRZ-SKNVOMKLSA-N
InChI
InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h1-5,8-10H/t2-,3+,4-,5+/m0/s1
Canonical SMILES
O=CC(O)C1OC(=O)C(O)C1O
Isomeric SMILES
C(=O)[C@@H]([C@@H]1[C@@H]([C@@H](C(=O)O1)O)O)O

Synonyms

  • D-Glucurono-6,3-lactone
  • D-Glucuronolactone
  • Glucurolactone
  • D-Glucurone
  • Glucurone
  • D-Glucuronic acid lactone
  • Glucuronosan
  • Guronsan
  • Glucoxy
  • Glucurolactona
  • Glucurolactonum
  • Glucuronolattone
  • Dicurone
  • D-Glucofuranuronic acid, gamma-lactone
  • D-Glucuronic acid, gamma-lactone
  • Gluronsan
  • (2R)-2-[(2S,3R,4S)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetaldehyde
  • gamma-Lactone of D-glucofuranuronic acid
  • glucuronic acid, gamma-lactone
  • (2R)-2-((2S,3R,4S)-3,4-dihydroxy-5-oxooxolan-2-yl)-2-hydroxyacetaldehyde
  • GlyTouCan:G10736YH
  • D-Glucurono-3,6-lactone
  • d(+)-glucurono-3,6-lactone
  • Glucurono-6,3-lactone
  • Glucuron
Show all 34 synonyms
  • D-Glucuronic acid, g-lactone
  • Glucuronic acid lactone
  • D-(+)-Glucurono-3,6-lactone
  • Reulatt S.S.
  • (R)-2-((2S,3R,4S)-3,4-dihydroxy-5-oxotetrahydrofuran-2-yl)-2-hydroxyacetaldehyde
  • Glucurolactone (INN)
  • Glucuronolactone (JAN)
  • D-Glucurono-gamma-lactone
  • gamma-Glukurolakton

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Liquidexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
176.12 g/molcalc.
Exact mass
176.0321 Dacalc.
LogP (octanol/water)
-2.81calc.
Topological polar surface area
104.1 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
2calc.
Heavy atoms
12calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.67calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCO1

O=C1CCCO1

1 ring, 6 atoms, the gamma-Butyrolactone ring system.

1,692 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Glucuronolactone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 40 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

40 suppliers in 11 countries

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Glucuronolactone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name GLUCURONOLACTONE(skin conditioning)

Roles

  • animal metabolite
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite

Functional uses

  • Humectant
  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Glucuronolactone is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Glucuronolactone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Glucuronolactone, based on the data on this page

What is Glucuronolactone?

D-glucurono-6,3-lactone is a glucuronolactone. It has a role as a mouse metabolite and a human metabolite. It is functionally related to a D-glucuronic acid.

What is the CAS number of Glucuronolactone?

The CAS registry number of Glucuronolactone is 32449-92-6. Other or deprecated CAS numbers: 63-29-6, 6814-06-8.

What is the molecular formula and weight of Glucuronolactone?

The molecular formula of Glucuronolactone is C6H8O6 and its molar mass is 176.12 g/mol.

What is Glucuronolactone used for?

Use classes: Cosmetics.

Is Glucuronolactone hazardous?

Glucuronolactone carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Glucuronolactone?

Glucuronolactone is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Glucuronolactone?

CompoundList lists 40 suppliers of Glucuronolactone in China, United States, Germany, India and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Glucuronolactone in India?

2 suppliers in India list Glucuronolactone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Glucuronolactone?

Suppliers quote Glucuronolactone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Glucuronolactone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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