Erythorbic acid
Also known as D-Isoascorbic acid, Isoascorbic acid, D-Araboascorbic acid
Key facts
What buyers check first
- Appearance
- Shiny granular crystals from water or dioxane
- Melting point
- 174 °C
- Solubility
- In water, 40 g in 100 mL water at 25 °C
- HS code
- 293220
- Category
- Food antioxidants

What is Erythorbic acid?
Plain description, key identifiers and synonyms
D-isoascorbic acid is an ascorbic acid.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
- CAS number
- 89-65-6 CAS number cross-checked
- EC number
- 201-928-0
- Molecular formula
- C6H8O6
- UNII
- 311332OII1
- MDL number
- MFCD00005378
- INCI name
- ERYTHORBIC ACID
- InChIKey
- CIWBSHSKHKDKBQ-DUZGATOHSA-N
- InChI
- InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5-/m1/s1
- Canonical SMILES
- O=C1OC(C(O)CO)C(O)=C1O
- Isomeric SMILES
- C([C@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O
Synonyms
- D-Isoascorbic acid
- Isoascorbic acid
- D-Araboascorbic acid
- D-Erythorbic acid
- Araboascorbic acid
- Isovitamin C
- Glucosaccharonic acid
- Erycorbin
- Neo-cebicure
- Saccharosonic acid
- Mercate 5
- D-erythro-3-Ketohexonic acid lactone
- D-erythro-3-Oxohexonic acid lactone
- 2,3-Didehydro-D-erythro-hexono-1,4-lactone
- (2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
- 3-Keto-D-erythro-hexonic acid gamma-lactone
- (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
- erythroascorbic acid
- (2R)-2-((1R)-1,2-dihydroxyethyl)-3,4-dihydroxy-2H-furan-5-one
- (5R)-5-((1R)-1,2-Dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one
- INS NO.315
- (5R)-5-((1R)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, D-erythro-hex-2-enono-1,4-lactone
- D-erythro-ascorbic acid
- D-(-)-Isoascorbic acid
- (R)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one
Show all 37 synonymsShow fewer synonyms
- D-soascorbic acid
- D-erythro-Hex-2-enonic acid, g-lactone
- D(-)-Isoascorbic Acid (Erythorbic Acid)
- D-erythro-hex-2-enonic acid gamma-lactone
- Sodium Ascorbate EP Impurity F
- D-Ascorbic acid, iso
- D-erythro-hex-2-enono-1,4-lactone
- D-Isoascorbic acid 1000 microg/mL in Acetonitrile
- Erythroascorbic acid, D-
- (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one
- Araboascorbic acid, D-
- D(-?)?-?Isoascorbic Acid (Erythorbic Acid)
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Shiny granular crystals from water or dioxaneexp.Measured value |
|---|---|
| Melting point | 174 °Cexp.Measured value |
| Solubility | In water, 40 g in 100 mL water at 25 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 176.12 g/molcalc.Computed value |
|---|---|
| Exact mass | 176.0321 Dacalc.Computed value |
| LogP (octanol/water) | -1.41calc.Computed value |
| Topological polar surface area | 107.2 Ųcalc.Computed value |
| Hydrogen bond donors | 4calc.Computed value |
| Hydrogen bond acceptors | 6calc.Computed value |
| Rotatable bonds | 2calc.Computed value |
| Heavy atoms | 12calc.Computed value |
| Rings | 1calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.5calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 2calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H335May cause respiratory irritation.
Precautionary statements (16)
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidErythorbic acid suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, ChangzhouUnclaimed profileErythorbic AcidGrade, purity and minimum order on requestPrice on request
- China, Wuxi ManufacturerUnclaimed profileErythorbic AcidGrade, purity and minimum order on requestPrice on request
- Thailand, Lat KrabangUnclaimed profileErythorbic AcidGrade, purity and minimum order on requestPrice on request
- United StatesUnclaimed profileErythorbic AcidGrade, purity and minimum order on requestPrice on request
- NetherlandsUnclaimed profileErythorbic AcidGrade, purity and minimum order on requestPrice on request
- United StatesUnclaimed profileD-Araboascorbic acidGrade, purity and minimum order on requestPrice on request
- JapanUnclaimed profileErythorbic AcidGrade, purity and minimum order on requestPrice on request
- SingaporeUnclaimed profileErythorbic AcidGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileErythorbic AcidGrade, purity and minimum order on requestPrice on request
- China, Wuxi ManufacturerUnclaimed profileErythorbic AcidGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
72 suppliers in 18 countries
- United States24
- China20
- Germany3
- United Kingdom2
- India2
- Japan2
- and 12 more countries
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Erythorbic acid price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant.
Reported uses
Table: Reported uses (ppm) for Erythorbic acid [Table#1683].
Antioxidant especially in brewing industry, reducing agent in photography.
Synthetic flavor.
Industrial uses: Reducing agent, Preservative.
Consumer uses: Preservative.
Use classes: Food additives, Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name ERYTHORBIC ACID(antioxidant)
Pharmacological actions
- Antioxidants
Functional uses
- Antioxidant
- Biocide
- Chemical reaction regulator
- Dye
- Flavouring and nutrient
- Food preservative
- Fragrance
Cosmetic functions
- Antioxidant
How it is made
Erythorbic acid is synthesized by the reaction between methyl 2-keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose and produced from Penicillium spp.
Erythorbic acid can also be prepared by reacting 2-keto-D-gluconate with sodium methoxide, synthesized from sucrose, or naturally produced by Penicililum species. Sodium erythorbate is prepared from D-glucose by a combination of biosynthesis and chemical synthesis via the intermediate 2-keto-D-gluconic acid.
Erythorbic acid is produced by the fermentation of D-glucose to 2-keto-D-gluconic acid by Pseudomonas fluorescens bacteria. The fermentation product is esterified and heated in basic solution to yield sodium erythorbate. Upon acidification of the salt in a water-methanol solution, erythorbic acid is formed.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
- Food additive
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Erythorbic acid is traded under.
Lactones
- United States14.2%
- India * partner reported13.5%
- Brazil8.5%
* Partner reported figures, a lower bound.
The HS code shown for Erythorbic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Erythorbic acid, based on the data on this page
What is Erythorbic acid?
What is the CAS number of Erythorbic acid?
What is the molecular formula and weight of Erythorbic acid?
What is Erythorbic acid used for?
Is Erythorbic acid hazardous?
What is the HS code of Erythorbic acid?
Where can I buy Erythorbic acid?
Where can I buy Erythorbic acid in India?
What is the price of Erythorbic acid?
Guides for buyers
Practical guides that help when you source, ship or handle Erythorbic acid
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
- Article, QualityWhat a certificate of analysis should containThe parts of a complete COA, how to read it against your specification, the warning signs of a weak or copied certificate and how to verify results.Read
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