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Steroids and sterols

Guggulsterone

Also known as Pregna-4,17(20)-diene-3,16-dione, (8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione, Guglip

CAS 95975-55-6Formula C21H28O2Molar mass 312.45 g/molEC 609-604-4
GHS signal word: Warning. Pictograms: Harmful or irritant 21 suppliers listed
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Guggulsterone chemical structure, C21H28O2, CAS 95975-55-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
95975-55-6
Formula
C21H28O2
Molar mass
312.45 g/mol
EC number
609-604-4
HS code
293729
Category
Steroids and sterols

What is Guggulsterone?

Plain description, key identifiers and synonyms

Guggulsterone is a 3-hydroxy steroid. It has a role as an androgen.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
CAS number
95975-55-6 CAS number cross-checkedOther or deprecated CAS: 39025-23-5
EC numbers
609-604-4, 982-588-7
Molecular formula
C21H28O2
UNII
6CST3U34GN
MDL number
MFCD01310757
InChIKey
WDXRGPWQVHZTQJ-OSJVMJFVSA-N
InChI
InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
Canonical SMILES
CC=C1C(=O)CC2C3CCC4=CC(=O)CCC4(C)C3CCC12C
Isomeric SMILES
C/C=C/1\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

Synonyms

  • Pregna-4,17(20)-diene-3,16-dione
  • (8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
  • Guglip
  • gugulipid
  • guggulipid
  • (8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta(a)phenanthrene-3,16-dione
  • (1R,2R,10S,11S,14E,15S)-14-(1-methoxyethylidene)-2,15-dimethyltetracyclo(8.7.0.0^(2,7).0^(11,15))heptadec-6-ene-5,13-dione
  • (Z)-Guggulsterone
  • Z-Guggulsterone
  • Guggulsterone E&Z
  • Cis-Guggulsterone
  • Guggulsterone z
  • Guggulsterone, (Z)-
  • (Z)-Pregna-4,17(20)-diene-3,16-dione
  • Pregna-4,17(20)-diene-3,16-dione, (17Z)-
  • (1Z,3aS,3bR,9aR,9bS,11aS)-1-ethylidene-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-2,7-dione
  • Guggulsterone, Guglip, Gugulipid,
  • (17Z)-Pregna-4,17(20)-diene-3,16-dione
  • Guggulsterones Z
  • (17Z)-Guggulsterone
  • Guggulsterones E&Z
  • Guggulsterone pound pregna-4,17-diene-3,16-dione pound(c)
  • 4,17(20)-cis-Pregnadiene-3,6-dione
  • (3aS,3bR,9aR,9bS,11aS)-1-ethylidene-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-2,7-dione
  • (Z&E)-Guggulsterone
Show all 32 synonyms
  • Guggulsterone z-form
  • (Z)-Guggulsterone, analytical standard
  • (17Z)-pregna-4,17-diene-3,16-dione
  • Z-Pregna-4,17(20)-diene-3,16-dione
  • (Z)-Guggulsterone, >=89% (HPLC), powder
  • Guggulsterone z (constituent of guggul)
  • Guggulsterone Z, United States Pharmacopeia (USP) Reference Standard

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
312.45 g/molcalc.
Exact mass
312.2089 Dacalc.
LogP (octanol/water)
4.64calc.
Topological polar surface area
34.14 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
23calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.71calc.
Formal charge
0calc.
Stereocentres
5calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C=C1C(=O)CC2C1CCC1C3CCC(=O)C=C3CCC21

C=C1C(=O)CC2C1CCC1C3CCC(=O)C=C3CCC21

4 rings, 20 atoms.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
Precautionary statements (6)
  • P264Wash skin thoroughly after handling.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Guggulsterone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 21 suppliers
21 of 21 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

21 suppliers in 7 countries

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Guggulsterone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • agonist
  • androgen
  • hormone
  • molecular messenger
  • sex hormone

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Guggulsterone is traded under.

HS 2937.29Indicative HS code

Steroidal hormones, their derivatives and structural analogues, other

World exports in 2024
$2.32B
+5.7% vs 2023, imports $2.41B
2019 to 2024
Top exporters
  1. Belgium25.3%
  2. United States24.9%
  3. China13.0%
Top importers
  1. Italy18.0%
  2. Canada13.0%
  3. Belgium12.2%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Guggulsterone is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Guggulsterone, based on the data on this page

What is Guggulsterone?

Guggulsterone is a 3-hydroxy steroid. It has a role as an androgen.

What is the CAS number of Guggulsterone?

The CAS registry number of Guggulsterone is 95975-55-6. Other or deprecated CAS numbers: 39025-23-5.

What is the molecular formula and weight of Guggulsterone?

The molecular formula of Guggulsterone is C21H28O2 and its molar mass is 312.45 g/mol.

What is Guggulsterone used for?

Known uses and roles of Guggulsterone include agonist, androgen, hormone, molecular messenger and sex hormone.

Is Guggulsterone hazardous?

Guggulsterone carries the GHS signal word "Warning". Main hazards: causes skin irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Guggulsterone?

Guggulsterone is usually classified under HS code 293729 (Steroidal hormones, their derivatives and structural analogues, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Guggulsterone?

CompoundList lists 21 suppliers of Guggulsterone in China, United States, Bangladesh, Germany and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Guggulsterone in India?

1 supplier in India list Guggulsterone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Guggulsterone?

Suppliers quote Guggulsterone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Guggulsterone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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