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Steroids and sterols

Dydrogesterone

Also known as Isopregnenone, Hydrogesterone, Duphaston

CAS 152-62-5Formula C21H28O2Molar mass 312.45 g/molEC 205-806-8
GHS signal word: Danger. Pictograms: Serious health hazard, Hazardous to the environment 75 suppliers listed
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Dydrogesterone chemical structure, C21H28O2, CAS 152-62-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from acetone + hexane
Melting point
170 °C
Solubility
Soluble in acetone, chloroform (1 in 2), ethanol (1 in 40) and diethyl ether (1 in 200),…
HS code
293723
Category
Steroids and sterols
Illustrative photo, a shrink wrapped pallet of kraft paper sacks in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Dydrogesterone?

Plain description, key identifiers and synonyms

Dydrogesterone is a 20-oxo steroid and a 3-oxo-Delta(4) steroid. It has a role as a progestin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
CAS number
152-62-5 CAS number cross-checked
EC number
205-806-8
Molecular formula
C21H28O2
UNII
90I02KLE8K
MDL number
MFCD00867864
InChIKey
JGMOKGBVKVMRFX-HQZYFCCVSA-N
InChI
InChI=1S/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4-5,12,16-19H,6-11H2,1-3H3/t16-,17+,18-,19+,20+,21+/m0/s1
Canonical SMILES
CC(=O)C1CCC2C3C=CC4=CC(=O)CCC4(C)C3CCC12C
Isomeric SMILES
CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@@H]3[C@H]2C=CC4=CC(=O)CC[C@@]34C)C

Synonyms

  • Isopregnenone
  • Hydrogesterone
  • Duphaston
  • Gynorest
  • Hydrogestrone
  • Gestatron
  • Retrone
  • Diphaston
  • Dufaston
  • Duvaron
  • Terolut
  • Prodel
  • 10alpha-Isopregnenone
  • Retro-6-dehydroprogesterone
  • Didrogesterone
  • Dydrogesteronum
  • delta(6)-Retroprogesterone
  • didrogesterona
  • 6-Dehydro-retro-progesterone
  • delta(sup 6)-Retroprogesterone
  • 9beta,10alpha-Pregna-4,6-diene-3,20-dione
  • Retroprogesterone, 6-dehydro-
  • (8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
  • 6-Dehydro-9beta,10alpha-progesterone
  • (9-beta,10-alpha)-Pregna-4,6-diene-3,20-dione
Show all 36 synonyms
  • Pregna-4,6-diene-3,20-dione, (9beta,10alpha)-
  • 9-beta,10-alpha-Pregna-4,6-diene-3,20-dione
  • Dehydrogesterone
  • 6-Dehydro-9 beta-10 alpha-progesterone
  • dibrogesterone
  • 6 Dehydro 9 beta 10 alpha progesterone
  • Duphaston-hrt
  • (1R,2S,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo(8.7.0.0^(2,7).0^(11,15))heptadeca-6,8-dien-5-one
  • (1R,2S,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-6,8-dien-5-one
  • (8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta(a)phenanthren-3-one
  • Dydrogesterona

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from acetone + hexaneexp.
Odour
Odorlessexp.
Melting point
170 °Cexp.
Solubility
Soluble in acetone, chloroform (1 in 2), ethanol (1 in 40) and diethyl ether (1 in 200), slightly soluble in fixed oils, sparingly soluble in methanol.exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
312.45 g/molcalc.
Exact mass
312.2089 Dacalc.
LogP (octanol/water)
4.5calc.
Topological polar surface area
34.14 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
23calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.71calc.
Formal charge
0calc.
Stereocentres
6calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C2C=CC3C4CCCC4CCC3C2CC1

O=C1C=C2C=CC3C4CCCC4CCC3C2CC1

4 rings, 18 atoms.

106 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H372Causes damage to organs through prolonged or repeated exposure.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (7)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P319Get medical help if you feel unwell.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Dydrogesterone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 75 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

75 suppliers in 12 countries

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Dydrogesterone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Progestins

Roles

  • agonist
  • hormone
  • molecular messenger
  • progestin
  • progestogen
  • sex hormone

How it is made

It is believed to be prepared commercially from lumisterol (9beta,10alpha-ergosta-5,7,22-trien-3beta-ol derived from ultra-violet-irradiated ergosterol) via a multistep synthesis involving oxidation, isomerization, lithium reduction, ozonolysis of the side-chain and a final zinc reduction

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dydrogesterone is traded under.

HS 2937.23Indicative HS code

Oestrogens and progestogens

World exports in 2024
$762M
−2.3% vs 2023, imports $693M
2019 to 2024
Top exporters
  1. China42.9%
  2. Italy18.4%
  3. Netherlands8.9%
Top importers
  1. India * partner reported12.1%
  2. United States11.0%
  3. Belgium8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Dydrogesterone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dydrogesterone, based on the data on this page

What is Dydrogesterone?

Dydrogesterone is a 20-oxo steroid and a 3-oxo-Delta(4) steroid. It has a role as a progestin.

What is the CAS number of Dydrogesterone?

The CAS registry number of Dydrogesterone is 152-62-5.

What is the molecular formula and weight of Dydrogesterone?

The molecular formula of Dydrogesterone is C21H28O2 and its molar mass is 312.45 g/mol.

What is Dydrogesterone used for?

Known uses and roles of Dydrogesterone include agonist, hormone, molecular messenger, progestin, progestogen and 2 more.

Is Dydrogesterone hazardous?

Dydrogesterone carries the GHS signal word "Danger". Main hazards: causes damage to organs through prolonged or repeated exposure, very toxic to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Dydrogesterone?

Dydrogesterone is usually classified under HS code 293723 (Oestrogens and progestogens). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dydrogesterone?

CompoundList lists 75 suppliers of Dydrogesterone in China, United States, India, Bangladesh and 8 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Dydrogesterone in India?

9 suppliers in India list Dydrogesterone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Dydrogesterone?

Suppliers quote Dydrogesterone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dydrogesterone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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