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Steroids and sterols

Ethisterone

Also known as Aethisteron, Etisterona, Nugestoral

CAS 434-03-7Formula C21H28O2Molar mass 312.45 g/molEC 207-096-5
GHS signal word: Danger. Pictograms: Serious health hazard 19 suppliers listed
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Ethisterone chemical structure, C21H28O2, CAS 434-03-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
434-03-7
Formula
C21H28O2
Molar mass
312.45 g/mol
EC number
207-096-5
HS code
293723
Category
Steroids and sterols

What is Ethisterone?

Plain description, key identifiers and synonyms

Ethisterone is a 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol. It has a role as a drug metabolite and a progestin. It is a tertiary alcohol, a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and a terminal acetylenic compound. It is functionally related to a testosterone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS number
434-03-7 CAS number cross-checked
EC number
207-096-5
Molecular formula
C21H28O2
UNII
P201BVY1MJ
MDL number
MFCD00003656
InChIKey
CHNXZKVNWQUJIB-CEGNMAFCSA-N
InChI
InChI=1S/C21H28O2/c1-4-21(23)12-9-18-16-6-5-14-13-15(22)7-10-19(14,2)17(16)8-11-20(18,21)3/h1,13,16-18,23H,5-12H2,2-3H3/t16-,17+,18+,19+,20+,21+/m1/s1
Canonical SMILES
C#CC1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C
Isomeric SMILES
C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@]4(C#C)O)C

Synonyms

  • Aethisteron
  • Etisterona
  • Nugestoral
  • Syngestrotabs
  • Trosinone
  • Pregneninolone
  • Ora-Lutin
  • Ethynyltestosterone
  • 17alpha-Ethynyltestosterone
  • Aethisteronum
  • Ethisteronum
  • Progestolets
  • Anhydrohydroxyprogesterone
  • Anhydroxyprogesterone
  • Prodroxan
  • Produxan
  • Progestab
  • Pranone
  • Etisterone
  • Praegninum
  • Progestoral
  • 17alpha-Ethinyltestosterone
  • 17alpha-Ethinyl testosterone
  • (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
  • 17alpha-Ethynyl-17beta-hydroxyandrost-4-en-3-one
Show all 38 synonyms
  • 17-beta-Hydroxy-17-alpha-ethynyl-4-androsten-3-one
  • 17-Ethynyl-17beta-hydroxyandrost-4-en-3-one
  • Pregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)-
  • 17 alpha Ethynyltestosterone
  • 17 alpha-Ethynyltestosterone
  • (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta(a)phenanthren-3-one
  • Ethinone
  • Pregnin
  • (17alpha)-17-hydroxypregn-4-en-20-yn-3-one
  • (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
  • 17-Ethinyltestosterone
  • 17-hydroxy-17alpha-pregn-4-en-20-yn-3-one
  • (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
312.45 g/molcalc.
Exact mass
312.2089 Dacalc.
LogP (octanol/water)
3.88calc.
Topological polar surface area
37.3 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
23calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.76calc.
Formal charge
0calc.
Stereocentres
6calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C2CCC3C4CCCC4CCC3C2CC1

O=C1C=C2CCC3C4CCCC4CCC3C2CC1

4 rings, 18 atoms.

1,419 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H360May damage fertility or the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ethisterone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 19 suppliers
19 of 19 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

19 suppliers in 4 countries

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Ethisterone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Roles

  • agonist
  • androgen
  • animal metabolite
  • drug metabolite
  • eukaryotic metabolite
  • hormone
  • human metabolite
  • human xenobiotic metabolite
  • mammalian metabolite
  • metabolite
  • molecular messenger
  • progestin
  • progestogen
  • sex hormone
  • xenobiotic metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ethisterone is traded under.

HS 2937.23Indicative HS code

Oestrogens and progestogens

World exports in 2024
$762M
−2.3% vs 2023, imports $693M
2019 to 2024
Top exporters
  1. China42.9%
  2. Italy18.4%
  3. Netherlands8.9%
Top importers
  1. India * partner reported12.1%
  2. United States11.0%
  3. Belgium8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ethisterone is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ethisterone, based on the data on this page

What is Ethisterone?

Ethisterone is a 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol. It has a role as a drug metabolite and a progestin.

What is the CAS number of Ethisterone?

The CAS registry number of Ethisterone is 434-03-7.

What is the molecular formula and weight of Ethisterone?

The molecular formula of Ethisterone is C21H28O2 and its molar mass is 312.45 g/mol.

What is Ethisterone used for?

Use classes: Pharmaceuticals.

Is Ethisterone hazardous?

Ethisterone carries the GHS signal word "Danger". Main hazards: may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ethisterone?

Ethisterone is usually classified under HS code 293723 (Oestrogens and progestogens). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ethisterone?

CompoundList lists 19 suppliers of Ethisterone in China, United States, Hong Kong and Mexico. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ethisterone?

Suppliers quote Ethisterone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ethisterone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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