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Impurities and reference standards

Hydroxy dabrafenib

Also known as Dabrafenib metabolite M7, N-[3-[5-(2-aminopyrimidin-4-yl)-2-(1-hydroxy-2-methylpropan-2-yl)-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide, Benzenesulfonamide, N-(3-(5-(2-amino-4-pyrimidinyl)-2-(2-hydroxy-1,1-dimethylethyl)-4-thiazolyl)-2-fluorophenyl)-2,6-difluoro-

CAS 1195767-77-1Formula C23H20F3N5O3S2Molar mass 535.57 g/mol
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Hydroxy dabrafenib chemical structure, C23H20F3N5O3S2, CAS 1195767-77-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1195767-77-1
Formula
C23H20F3N5O3S2
Molar mass
535.57 g/mol
HS code
293590
Category
Impurities and reference standards

What is Hydroxy dabrafenib?

Plain description, key identifiers and synonyms

Hydroxy dabrafenib is a chemical substance with the molecular formula C23H20F3N5O3S2 and a molar mass of 535.57 g/mol. Its CAS registry number is 1195767-77-1. The IUPAC name is N-[3-[5-(2-aminopyrimidin-4-yl)-2-(1-hydroxy-2-methylpropan-2-yl)-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[3-[5-(2-aminopyrimidin-4-yl)-2-(1-hydroxy-2-methylpropan-2-yl)-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
CAS number
1195767-77-1
Molecular formula
C23H20F3N5O3S2
UNII
2N549WYF8O
InChIKey
XUORVRVRUPDXCP-UHFFFAOYSA-N
InChI
InChI=1S/C23H20F3N5O3S2/c1-23(2,11-32)21-30-18(19(35-21)16-9-10-28-22(27)29-16)12-5-3-8-15(17(12)26)31-36(33,34)20-13(24)6-4-7-14(20)25/h3-10,31-32H,11H2,1-2H3,(H2,27,28,29)
SMILES (canonical and isomeric)
CC(C)(CO)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F

Synonyms

  • Dabrafenib metabolite M7
  • N-[3-[5-(2-aminopyrimidin-4-yl)-2-(1-hydroxy-2-methylpropan-2-yl)-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
  • Benzenesulfonamide, N-(3-(5-(2-amino-4-pyrimidinyl)-2-(2-hydroxy-1,1-dimethylethyl)-4-thiazolyl)-2-fluorophenyl)-2,6-difluoro-
  • Hydroxy dabrafenib?
  • GSK 2285403
  • Dabrafenib Impurity N2
  • N-[3-[5-(2-aminopyrimidin-4-yl)-2-(2-hydroxy-1,1-dimethyl-ethyl)thiazol-4-yl]-2-fluoro-phenyl]-2,6-difluoro-benzenesulfonamide
  • N-{3-[5-(2-amino-4-pyrimidinyl)-2-(2-hydroxy-1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
535.57 g/molcalc.
Exact mass
535.096 Dacalc.
LogP (octanol/water)
4.34calc.
Topological polar surface area
131.1 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
7calc.
Heavy atoms
36calc.
Rings
4calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.17calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=S(=O)(Nc1cccc(-c2ncsc2-c2ccncn2)c1)c1ccccc1

O=S(=O)(Nc1cccc(-c2ncsc2-c2ccncn2)c1)c1ccccc1

4 rings, 27 atoms.

15 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Hydroxy dabrafenib suppliers

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Hydroxy dabrafenib price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydroxy dabrafenib is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydroxy dabrafenib is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydroxy dabrafenib, based on the data on this page

What is Hydroxy dabrafenib?

Hydroxy dabrafenib is a chemical substance with the molecular formula C23H20F3N5O3S2 and a molar mass of 535.57 g/mol. Its CAS registry number is 1195767-77-1. The IUPAC name is N-[3-[5-(2-aminopyrimidin-4-yl)-2-(1-hydroxy-2-methylpropan-2-yl)-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide.

What is the CAS number of Hydroxy dabrafenib?

The CAS registry number of Hydroxy dabrafenib is 1195767-77-1.

What is the molecular formula and weight of Hydroxy dabrafenib?

The molecular formula of Hydroxy dabrafenib is C23H20F3N5O3S2 and its molar mass is 535.57 g/mol.

Is Hydroxy dabrafenib hazardous?

No GHS hazard classification for Hydroxy dabrafenib is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Hydroxy dabrafenib?

Hydroxy dabrafenib is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydroxy dabrafenib?

Post a free request on CompoundList and suppliers of Hydroxy dabrafenib will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Hydroxy dabrafenib?

Suppliers quote Hydroxy dabrafenib on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydroxy dabrafenib

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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