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Impurities and reference standards

Hydroxycamptothecin

Also known as 10-Hydroxycamptothecin, (S)-10-Hydroxycamptothecin, 10-hydroxycamptothecine

CAS 19685-09-7Formula C20H16N2O5Molar mass 364.36 g/molEC 613-598-9
GHS signal word: Warning. Pictograms: Harmful or irritant 56 suppliers listed
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Hydroxycamptothecin chemical structure, C20H16N2O5, CAS 19685-09-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
19685-09-7
Formula
C20H16N2O5
Molar mass
364.36 g/mol
EC number
613-598-9
HS code
293499
Category
Impurities and reference standards

What is Hydroxycamptothecin?

Plain description, key identifiers and synonyms

10-Hydroxycamptothecin is a pyranoindolizinoquinoline.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
CAS number
19685-09-7 CAS number cross-checkedOther or deprecated CAS: 64439-81-2
EC numbers
613-598-9, 805-668-4
Molecular formula
C20H16N2O5
UNII
9Z01632KRV
MDL number
MFCD02093100
InChIKey
HAWSQZCWOQZXHI-FQEVSTJZSA-N
InChI
InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1
Canonical SMILES
CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(O)ccc3nc2-1
Isomeric SMILES
CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O

Synonyms

  • 10-Hydroxycamptothecin
  • (S)-10-Hydroxycamptothecin
  • 10-hydroxycamptothecine
  • 10-HCPT
  • (19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
  • (19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo(11.8.0.02,11.04,9.015,20)henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
  • 10-Hydroxy camptothecin
  • (S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
  • (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
  • Hydroxycamptothecine
  • Camptothecin, hydroxy-
  • Camptothecine, 10-hydroxy-
  • 10-Hydroxy-Camptothecin
  • Irinotecan EP Impurity B
  • (S)-4-ethyl-4,9-dihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione
  • Camptothecin, 10-hydroxy-
  • 4-Ethyl-4,9-dihydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione
  • (20S)-4-Ethyl-4,9-dihydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione
  • 4-Ethyl-4,9-dihydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione (10-hydroxycamptothecin)
  • Hydroxycamptothecin-10
  • (S)-10-Hydroxycamptothecin hydrate
  • Camptothecin, 10-hydroxy
  • (4S)-4,9-Dihydroxy-4-ethyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
  • (S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione ((S)-10-Hydroxycamptothecin)
  • 10-Hydroxy-CPT
Show all 33 synonyms
  • (+)-(S)-10-Hydroxycamptothecin
  • 10-Hydroxycamp-totecin
  • ethyl(dihydroxy)[?]dione
  • 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, hydrate, (S)-
  • DivK1c_006859
  • Camptothecin 10-Hydroxy Impurity
  • (+)-10-Hydroxycamptothecin
  • (S)-10-Hydroxycamptothecin (Standard)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
364.36 g/molcalc.
Exact mass
364.1059 Dacalc.
LogP (octanol/water)
1.79calc.
Topological polar surface area
101.7 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
1calc.
Heavy atoms
27calc.
Rings
5calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1Cc2cc3n(c(=O)c2CO1)Cc1cc2ccccc2nc1-3

O=C1Cc2cc3n(c(=O)c2CO1)Cc1cc2ccccc2nc1-3

5 rings, 23 atoms.

307 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Hydroxycamptothecin suppliers

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All 56 suppliers
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Where suppliers are based

56 suppliers in 6 countries

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Hydroxycamptothecin price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antineoplastic Agents, Phytogenic

Roles

  • antineoplastic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydroxycamptothecin is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydroxycamptothecin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydroxycamptothecin, based on the data on this page

What is Hydroxycamptothecin?

10-Hydroxycamptothecin is a pyranoindolizinoquinoline.

What is the CAS number of Hydroxycamptothecin?

The CAS registry number of Hydroxycamptothecin is 19685-09-7. Other or deprecated CAS numbers: 64439-81-2.

What is the molecular formula and weight of Hydroxycamptothecin?

The molecular formula of Hydroxycamptothecin is C20H16N2O5 and its molar mass is 364.36 g/mol.

What is Hydroxycamptothecin used for?

Known uses and roles of Hydroxycamptothecin include antineoplastic agent, pharmaceutical and antineoplastic agents, phytogenic.

Is Hydroxycamptothecin hazardous?

Hydroxycamptothecin carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Hydroxycamptothecin?

Hydroxycamptothecin is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydroxycamptothecin?

CompoundList lists 56 suppliers of Hydroxycamptothecin in China, United States, Germany, France and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Hydroxycamptothecin?

Suppliers quote Hydroxycamptothecin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydroxycamptothecin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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