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Analgesics and anti-inflammatories

Hydroxychloroquine

Also known as Oxichloroquine, Oxychlorochin, Hidroxicloroquina

CAS 118-42-3Formula C18H26ClN3OMolar mass 335.88 g/molEC 204-249-8
GHS signal word: Warning. Pictograms: Harmful or irritant 98 suppliers listed Drug substance
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Hydroxychloroquine chemical structure, C18H26ClN3O, CAS 118-42-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
118-42-3
Formula
C18H26ClN3O
Molar mass
335.88 g/mol
EC number
204-249-8
HS code
293349
Category
Analgesics and anti-inflammatories

What is Hydroxychloroquine?

Plain description, key identifiers and synonyms

Hydroxychloroquine is an aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions. It has a role as an anticoronaviral agent, an antirheumatic drug, an antimalarial and a dermatologic drug. It is a primary alcohol, an organochlorine compound, an aminoquinoline, a secondary amino compound and a tertiary amino compound. It is functionally related to a chloroquine. It is a conjugate base of a hydroxychloroquine(2+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol
CAS number
118-42-3 CAS number cross-checked
EC number
204-249-8
Molecular formula
C18H26ClN3O
UNII
4QWG6N8QKH
MDL number
MFCD00242707
InChIKey
XXSMGPRMXLTPCZ-UHFFFAOYSA-N
InChI
InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)
SMILES (canonical and isomeric)
CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO

Synonyms

  • Oxichloroquine
  • Oxychlorochin
  • Hidroxicloroquina
  • oxichlorochine
  • Polirreumin
  • Hydroxychloroquinum
  • 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol
  • Dolquine
  • 7-Chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline
  • 2-(N-(4-(7-Chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol
  • 7-Chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline
  • 7-Chloro-4-(5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl)aminoquinoline
  • (+-)-hydroxychloroquine
  • 2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol
  • Ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)-
  • Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-
  • Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-
  • Hydroxychlorochin
  • 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethan-1-ol
  • 7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline
  • 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline
  • idroxiclorochina
  • Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]ethylamino]-
  • 2-[{4-[(7-Chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethan-1-ol
  • hidroxychloroquine sulfate
Show all 37 synonyms
  • Plaquenil
  • WIN 1258
  • 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol
  • 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol
  • Hydroxychloroquine (INN)
  • 2-[[4-[(7-chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol
  • Oxichlorochinum
  • C18H26ClN3O
  • 2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol
  • HCQ
  • Idrossiclorochina
  • 2-[4-[(7-chloro-4-quinolyl)amino]pentyl-ethyl-amino]ethanol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
335.88 g/molcalc.
Exact mass
335.1764 Dacalc.
LogP (octanol/water)
3.78calc.
Topological polar surface area
48.39 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
9calc.
Heavy atoms
23calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2ncccc2c1

c1ccc2ncccc2c1

2 rings, 10 atoms, the Quinoline ring system.

21,766 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Hydroxychloroquine suppliers

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All 98 suppliers
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Where suppliers are based

98 suppliers in 16 countries

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Hydroxychloroquine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antimalarials
  • Antirheumatic Agents
  • Enzyme Inhibitors

Roles

  • PPAR modulator
  • agonist
  • anti-HIV agent
  • anti-inflammatory agent
  • anticoronaviral agent
  • antifungal agent
  • antiinfective agent
  • antimalarial
  • antimicrobial agent
  • antimicrobial drug
  • antineoplastic agent
  • antiparasitic agent
  • antiplasmodial drug
  • antiprotozoal drug
  • antirheumatic drug
  • antiviral agent
  • dermatologic drug
  • hypoglycemic agent
  • immunomodulator
  • immunosuppressive agent
  • insulin-sensitizing drug
  • pharmaceutical

Pharmacology

Hydroxychloroquine is an Antirheumatic Agent and Antimalarial.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydroxychloroquine is traded under.

HS 2933.49Indicative HS code

Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…

World exports in 2024
$939M
−14.6% vs 2023, imports $1.48B
2019 to 2024
Top exporters
  1. China30.1%
  2. India * partner reported16.7%
  3. Switzerland * partner reported14.1%
Top importers
  1. United Kingdom19.2%
  2. Germany16.0%
  3. Romania8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydroxychloroquine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydroxychloroquine, based on the data on this page

What is Hydroxychloroquine?

Hydroxychloroquine is an aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2.

What is the CAS number of Hydroxychloroquine?

The CAS registry number of Hydroxychloroquine is 118-42-3.

What is the molecular formula and weight of Hydroxychloroquine?

The molecular formula of Hydroxychloroquine is C18H26ClN3O and its molar mass is 335.88 g/mol.

What is Hydroxychloroquine used for?

Known uses and roles of Hydroxychloroquine include anti-inflammatories in pharmaceuticals, antidiabetics in pharmaceuticals, biochemical and pharmacological tools in research and laboratory, ppar modulator, agonist and 23 more.

Is Hydroxychloroquine hazardous?

Hydroxychloroquine carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Hydroxychloroquine?

Hydroxychloroquine is usually classified under HS code 293349 (Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydroxychloroquine?

CompoundList lists 98 suppliers of Hydroxychloroquine in United States, China, India, United Kingdom and 12 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Hydroxychloroquine in India?

13 suppliers in India list Hydroxychloroquine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Hydroxychloroquine?

Suppliers quote Hydroxychloroquine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydroxychloroquine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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