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Carbohydrates and sugars

Hydroxyethyl starch

Also known as Venofundin, Hydroxyethylstarch, HES 130/0.4

CAS 9005-27-0Formula C22H44O17Molar mass 580.58 g/molEC 618-410-9
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Hydroxyethyl starch chemical structure, C22H44O17, CAS 9005-27-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
9005-27-0
Formula
C22H44O17
Molar mass
580.58 g/mol
EC number
618-410-9
HS code
294000
Category
Carbohydrates and sugars

What is Hydroxyethyl starch?

Plain description, key identifiers and synonyms

Hydroxyethyl starch 130/0.4 is a Plasma Volume Expander. The mechanism of action of hydroxyethyl starch 130/0.4 is as an Osmotic Activity. The physiologic effect of hydroxyethyl starch 130/0.4 is by means of Increased Intravascular Volume.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol, 2-[[(2R,3R,4S,5R,6S)-3,4,5,6-tetrakis(2-hydroxyethoxy)oxan-2-yl]methoxy]ethanol
CAS number
9005-27-0 CAS number cross-checked
EC number
618-410-9
Molecular formula
C22H44O17
UNII
MOQ3RNM0SV
MDL number
MFCD00131356
InChIKey
DNZMDASEFMLYBU-RNBXVSKKSA-N
InChI
InChI=1S/C16H32O11.C6H12O6/c17-1-6-22-11-12-13(23-7-2-18)14(24-8-3-19)15(25-9-4-20)16(27-12)26-10-5-21;7-1-2-3(8)4(9)5(10)6(11)12-2/h12-21H,1-11H2;2-11H,1H2/t12-,13-,14+,15-,16+;2-,3-,4+,5-,6+/m11/s1
Canonical SMILES
OCC1OC(O)C(O)C(O)C1O.OCCOCC1OC(OCCO)C(OCCO)C(OCCO)C1OCCO
Isomeric SMILES
C(COC[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)OCCO)OCCO)OCCO)OCCO)O.C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O

Synonyms

  • Venofundin
  • Hydroxyethylstarch
  • HES 130/0.4
  • Volulyte
  • VetStarch
  • Hydrostarch
  • HYDROXYETHYL STARCH 130/0.4 Substitution
  • (2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol, 2-[[(2R,3R,4S,5R,6S)-3,4,5,6-tetrakis(2-hydroxyethoxy)oxan-2-yl]methoxy]ethanol
  • Expafusion
  • Plasmasteril
  • Bohramyl
  • Elohast
  • Hespander
  • Onkohas
  • Tetraspan
  • Elohes
  • Hydroxyathylstarke
  • Hespander injection
  • Hidroxietil almidon
  • HAS
  • Penford 260
  • Penford 280
  • Penford 290
  • Penford P 208
  • Essex 1360
Show all 31 synonyms
  • ASL 607
  • Hetastarch, Technical Grade
  • Pentastarch
  • Hydroxyethyl starch (high Mw) CRS
  • Hydroxyethyl starch (medium MW) CRS
  • (2S,3R,4S,5S,6R)-6-(hydroxymethyl)tetrahydropyran-2,3,4,5-tetrol, 2-[[(2R,3R,4S,5R,6S)-3,4,5,6-tetrakis(2-hydroxyethoxy)tetrahydropyran-2-yl]methoxy]ethanol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
580.58 g/molcalc.
Exact mass
580.2579 Dacalc.
LogP (octanol/water)
-6.36calc.
Topological polar surface area
266.9 Ųcalc.
Hydrogen bond donors
10calc.
Hydrogen bond acceptors
17calc.
Rotatable bonds
17calc.
Heavy atoms
39calc.
Rings
2calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
10calc.
Components
2calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCOCC1

C1CCOCC1

1 ring, 6 atoms, the Tetrahydropyran ring system.

12,069 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Hydroxyethyl starch suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 6 suppliers
6 of 6 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

6 suppliers in 3 countries

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Hydroxyethyl starch price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Polymers, Safer Chemical Classes.

Functional uses

  • Binder

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • Safer Choice ingredient list (USA)
  • TSCA inventory (USA)
    Status: Active in US commerce, Regulatory flags: Exempt from Chemical Data Reporting

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydroxyethyl starch is traded under.

HS 2940.00Indicative HS code

Sugar ethers, sugar acetals and sugar esters, and their salts, other than the products of heading 29.37…

World exports in 2024
$1.4B
−5.4% vs 2023, imports $1.42B
2019 to 2024
Top exporters
  1. Germany23.7%
  2. China20.6%
  3. United States11.5%
Top importers
  1. United States14.0%
  2. Japan7.4%
  3. Germany6.1%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydroxyethyl starch is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydroxyethyl starch, based on the data on this page

What is Hydroxyethyl starch?

Hydroxyethyl starch 130/0.4 is a Plasma Volume Expander. The mechanism of action of hydroxyethyl starch 130/0.4 is as an Osmotic Activity. The physiologic effect of hydroxyethyl starch 130/0.4 is by means of Increased Intravascular Volume.

What is the CAS number of Hydroxyethyl starch?

The CAS registry number of Hydroxyethyl starch is 9005-27-0.

What is the molecular formula and weight of Hydroxyethyl starch?

The molecular formula of Hydroxyethyl starch is C22H44O17 and its molar mass is 580.58 g/mol.

What is Hydroxyethyl starch used for?

Use classes: Polymers, Safer Chemical Classes.

Is Hydroxyethyl starch hazardous?

No GHS hazard classification for Hydroxyethyl starch is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Hydroxyethyl starch?

Hydroxyethyl starch is usually classified under HS code 294000 (Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydroxyethyl starch?

CompoundList lists 6 suppliers of Hydroxyethyl starch in China, United States and South Africa. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Hydroxyethyl starch?

Suppliers quote Hydroxyethyl starch on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydroxyethyl starch

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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