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Hydroxyprogesterone acetate

Also known as 17alpha-Acetoxyprogesterone, Prodox acetate, Acetoxyprogesterone

Hydroxyprogesterone acetate chemical structure, C23H32O4, CAS 302-23-8
2D chemical structure

Key facts

What buyers check first

CAS number
302-23-8
Formula
C23H32O4
Molar mass
372.51 g/mol
EC number
206-119-6
HS code
291539
Category
Impurities and reference standards

What is Hydroxyprogesterone acetate?

Plain description, key identifiers and synonyms

Hydroxyprogesterone acetate is a corticosteroid hormone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
CAS number
302-23-8 CAS number cross-checkedOther or deprecated CAS: 17308-02-0
EC numbers
206-119-6, 241-337-5
Molecular formula
C23H32O4
UNII
L124O66YSI
MDL number
MFCD00021156
InChIKey
VTHUYJIXSMGYOQ-KOORYGTMSA-N
InChI
InChI=1S/C23H32O4/c1-14(24)23(27-15(2)25)12-9-20-18-6-5-16-13-17(26)7-10-21(16,3)19(18)8-11-22(20,23)4/h13,18-20H,5-12H2,1-4H3/t18-,19+,20+,21+,22+,23+/m1/s1
Canonical SMILES
CC(=O)OC1(C(C)=O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C
Isomeric SMILES
CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)OC(=O)C

Synonyms

  • 17alpha-Acetoxyprogesterone
  • Prodox acetate
  • Acetoxyprogesterone
  • 17-Hydroxypregn-4-ene-3,20-dione acetate
  • Pregn-4-ene-3,20-dione, 17-(acetyloxy)-
  • 17-Acetoxyprogesterone
  • 17-Hydroxyprogesterone 17alpha-acetate
  • 17-(Acetyloxy)pregn-4-ene-3,20-dione
  • 17alpha-Acetoxypregnen-4-en-3,20-dion
  • 3,20-Dioxo-4-pregnen-17alpha-yl acetate
  • 3,20-Dioxopregn-4-en-17-yl acetate
  • Pregn-4-ene-3,20-dione, 17-hydroxy-, acetate
  • Megestrol acetate impurity k
  • 17-Hydroxyprogesterone acetate
  • Medroxyprogesterone acetate impurity h
  • 17alpha-hydroxy-4-pregnene-3,20-dione acetate
  • Megestrol acetate impurity k (ep impurity)
  • Medroxyprogesterone acetate impurity h (ep impurity)
  • 17-(Acetyloxy)progesterone
  • 17|A-Hydroxyprogesterone acetate
  • [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
  • 17alpha-acetoxy-progesterone
  • 17-alpha-Hydroxyprogesterone 17-acetate
  • (8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
  • 17alpha-Hydroxyprogesterone acetate
Show all 31 synonyms
  • Prokan
  • 17a-hydroxyprogesterone acetate
  • 3,20-Dioxopregn-4-en-17-yl Acetate (Hydroxyprogesterone Acetate)
  • Megestrol Acetate EP Impurity K
  • 17alpha-acetoxypregn-4-ene-3,20-dione
  • 17-a-Acetoxyprogesterone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
372.51 g/molcalc.
Exact mass
372.2301 Dacalc.
LogP (octanol/water)
4.41calc.
Topological polar surface area
60.44 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
27calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.78calc.
Formal charge
0calc.
Stereocentres
6calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C2CCC3C4CCCC4CCC3C2CC1

O=C1C=C2CCC3C4CCCC4CCC3C2CC1

4 rings, 18 atoms.

1,419 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H351Suspected of causing cancer.
  • H360May damage fertility or the unborn child.
  • H362May cause harm to breast-fed children.
  • H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (10)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P263Avoid contact during pregnancy and while nursing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Hydroxyprogesterone acetate suppliers

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Where suppliers are based

10 suppliers in 2 countries

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Hydroxyprogesterone acetate price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydroxyprogesterone acetate is traded under.

HS 2915.39Indicative HS code

Esters of acetic acid, other

World exports in 2024
$2.03B
+7.9% vs 2023, imports $1.95B
2019 to 2024
Top exporters
  1. China58.0%
  2. United States7.3%
  3. Germany6.5%
Top importers
  1. Singapore15.6%
  2. South Korea7.2%
  3. Indonesia6.9%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydroxyprogesterone acetate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydroxyprogesterone acetate, based on the data on this page

What is Hydroxyprogesterone acetate?

Hydroxyprogesterone acetate is a corticosteroid hormone.

What is the CAS number of Hydroxyprogesterone acetate?

The CAS registry number of Hydroxyprogesterone acetate is 302-23-8. Other or deprecated CAS numbers: 17308-02-0.

What is the molecular formula and weight of Hydroxyprogesterone acetate?

The molecular formula of Hydroxyprogesterone acetate is C23H32O4 and its molar mass is 372.51 g/mol.

What is Hydroxyprogesterone acetate used for?

Use classes: Pharmaceuticals.

Is Hydroxyprogesterone acetate hazardous?

Hydroxyprogesterone acetate carries the GHS signal word "Danger". Main hazards: suspected of causing cancer, may damage fertility or the unborn child, may cause harm to breast-fed children. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Hydroxyprogesterone acetate?

Hydroxyprogesterone acetate is usually classified under HS code 291539 (Esters of acetic acid, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydroxyprogesterone acetate?

CompoundList lists 10 suppliers of Hydroxyprogesterone acetate in China and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Hydroxyprogesterone acetate?

Suppliers quote Hydroxyprogesterone acetate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydroxyprogesterone acetate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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