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Hormones and steroids

Hydroxyprogesterone caproate

Also known as Delalutin, Primolut Depot, Hydroxyprogesterone hexanoate

CAS 630-56-8Formula C27H40O4Molar mass 428.61 g/molEC 211-138-8
GHS signal word: Danger. Pictograms: Serious health hazard 85 suppliers listed Drug substance
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Hydroxyprogesterone caproate chemical structure, C27H40O4, CAS 630-56-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
630-56-8
Formula
C27H40O4
Molar mass
428.61 g/mol
EC number
211-138-8
HS code
293723
Category
Hormones and steroids

What is Hydroxyprogesterone caproate?

Plain description, key identifiers and synonyms

Hydroxyprogesterone caproate is a corticosteroid hormone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate
CAS number
630-56-8 CAS number cross-checked
EC number
211-138-8
Molecular formula
C27H40O4
UNII
276F2O42F5
MDL number
MFCD00072134
InChIKey
DOMWKUIIPQCAJU-LJHIYBGHSA-N
InChI
InChI=1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1
Canonical SMILES
CCCCCC(=O)OC1(C(C)=O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C
Isomeric SMILES
CCCCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)C(=O)C

Synonyms

  • Delalutin
  • Primolut Depot
  • Hydroxyprogesterone hexanoate
  • Hormofort
  • Syngynon
  • Proluton Depot
  • Depo-Proluton
  • Teralutil
  • Hylutin
  • Makena
  • Pharlon
  • 17alpha-Hydroxyprogesterone caproate
  • Procyte depo
  • 17-alpha-hydroxy-progesterone caproate
  • 17-OHPC
  • 17alpha-Caproyloxypregn-4-ene-3,20-dione
  • 17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione
  • 17 alpha-hydroxyprogesterone caproate
  • Oxiprogesterone Caproate
  • 17-Hydroxypregn-4-ene-3,20-dione hexanoate
  • Pregn-4-ene-3,20-dione, 17-((1-oxohexyl)oxy)-
  • 3,20-Dioxopregn-4-en-17alpha-yl caproate
  • [(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate
  • Pregn-4-ene-3,20-dione, 17-[(1-oxohexyl)oxy]-
  • oxyprogesterone caproate
Show all 38 synonyms
  • 17-hydroxyprogesterone capronate
  • 17 Hydroxyprogesterone Capronate
  • 17 alpha-oxyprogesterone capronate
  • 17 alpha Oxyprogesterone Capronate
  • ((8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta(a)phenanthren-17-yl) hexanoate
  • 17 alpha Hydroxyprogesterone Caproate
  • Makena (autoinjector)
  • 17 alpha Hydroxy Progesterone Caproate
  • Caproate, 17-alpha-Hydroxy-Progesterone
  • Makena preservative free
  • 17alpha-CAPROYLOXY-P4
  • Hexanoic acid, 3,20-dioxopregn-4-en-17-yl ester
  • (1S,2R,10R,11S,14R,15S)-14-acetyl-2,15-dimethyl-5-oxotetracyclo(8.7.0.02,7.011,15)heptadec-6-en-14-yl hexanoate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
428.61 g/molcalc.
Exact mass
428.2927 Dacalc.
LogP (octanol/water)
5.97calc.
Topological polar surface area
60.44 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
31calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.82calc.
Formal charge
0calc.
Stereocentres
6calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C2CCC3C4CCCC4CCC3C2CC1

O=C1C=C2CCC3C4CCCC4CCC3C2CC1

4 rings, 18 atoms.

1,419 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H360May damage fertility or the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Hydroxyprogesterone caproate suppliers

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All 85 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

85 suppliers in 17 countries

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Hydroxyprogesterone caproate price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Estrogen Antagonists
  • Progestins

Pharmacology

Hydroxyprogesterone Caproate is a synthetic progestational agent similar to the endogenous progesterone used in hormone therapy or as a female contraceptive. Mimicking the action of progesterone, hydroxyprogesterone caporate binds to and activates nuclear progesterone receptors in the reproductive system and causes the ligand-receptor complex to be translocated to the nucleus where it binds to and promotes expression of target genes.

Read more

Due to the negative feedback mechanism seen with progesterone, this agent also blocks luteinizing hormone (LH) release from the pituitary gland, thereby leading to an inhibition of ovulation and an alteration in the cervical mucus and endometrium. Furthermore, without stimulation of LH, estrogen release from the ovaries is stopped, hence impeding the growth of estrogen-sensitive tumor cells.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydroxyprogesterone caproate is traded under.

HS 2937.23Indicative HS code

Oestrogens and progestogens

World exports in 2024
$762M
−2.3% vs 2023, imports $693M
2019 to 2024
Top exporters
  1. China42.9%
  2. Italy18.4%
  3. Netherlands8.9%
Top importers
  1. India * partner reported12.1%
  2. United States11.0%
  3. Belgium8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydroxyprogesterone caproate is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydroxyprogesterone caproate, based on the data on this page

What is Hydroxyprogesterone caproate?

Hydroxyprogesterone caproate is a corticosteroid hormone.

What is the CAS number of Hydroxyprogesterone caproate?

The CAS registry number of Hydroxyprogesterone caproate is 630-56-8.

What is the molecular formula and weight of Hydroxyprogesterone caproate?

The molecular formula of Hydroxyprogesterone caproate is C27H40O4 and its molar mass is 428.61 g/mol.

What is Hydroxyprogesterone caproate used for?

Use classes: Pharmaceuticals.

Is Hydroxyprogesterone caproate hazardous?

Hydroxyprogesterone caproate carries the GHS signal word "Danger". Main hazards: may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Hydroxyprogesterone caproate?

Hydroxyprogesterone caproate is usually classified under HS code 293723 (Oestrogens and progestogens). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydroxyprogesterone caproate?

CompoundList lists 85 suppliers of Hydroxyprogesterone caproate in United States, China, India, Germany and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Hydroxyprogesterone caproate in India?

9 suppliers in India list Hydroxyprogesterone caproate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Hydroxyprogesterone caproate?

Suppliers quote Hydroxyprogesterone caproate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydroxyprogesterone caproate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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