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Impurities and reference standards

Hydroxytolbutamide

Also known as hydroxymethyltolbutamide, Methylhydroxytolbutamide, 1-Butyl-3-(4-hydroxymethylphenyl)sulfonylurea

CAS 5719-85-7Formula C12H18N2O4SMolar mass 286.35 g/mol
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Hydroxytolbutamide chemical structure, C12H18N2O4S, CAS 5719-85-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
5719-85-7
Formula
C12H18N2O4S
Molar mass
286.35 g/mol
HS code
293590
Category
Impurities and reference standards

What is Hydroxytolbutamide?

Plain description, key identifiers and synonyms

4-hydroxytolbutamide is a urea that consists of 1-butylurea having a 4-hydroxymethylbenzenesulfonyl group attached at the 3-position. It has a role as a metabolite. It is a member of benzyl alcohols, a sulfonamide and a member of ureas.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-butyl-3-[4-(hydroxymethyl)phenyl]sulfonylurea
CAS number
5719-85-7 CAS number cross-checkedOther or deprecated CAS: 1185112-19-9
Molecular formula
C12H18N2O4S
UNII
52K8J94779
MDL number
MFCD00144466
InChIKey
SJRHYONYKZIRPM-UHFFFAOYSA-N
InChI
InChI=1S/C12H18N2O4S/c1-2-3-8-13-12(16)14-19(17,18)11-6-4-10(9-15)5-7-11/h4-7,15H,2-3,8-9H2,1H3,(H2,13,14,16)
SMILES (canonical and isomeric)
CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)CO

Synonyms

  • hydroxymethyltolbutamide
  • Methylhydroxytolbutamide
  • 1-Butyl-3-(4-hydroxymethylphenyl)sulfonylurea
  • N-((Butylamino)carbonyl)-4-(hydroxymethyl)benzenesulfonamide
  • Benzenesulfonamide, N-((butylamino)carbonyl)-4-(hydroxymethyl)-
  • Benzenesulfonamide, N-[(butylamino)carbonyl]-4-(hydroxymethyl)-
  • 4-Hydroxytolbutamide
  • Hydroxy Tolbutamide
  • 4-hydroxy Tolbutamide
  • N-(Butylaminocarbonyl)-4-hydroxymethylbenzenesulfonamide
  • 4 hydroxy tolbutamide
  • Hydroxymethylcarbutamide
  • N-(butylcarbamoyl)-4-(hydroxymethyl)benzenesulfonamide
  • N-(Butylamnocarbonyl)-4-hydroxymethylbenzenesulfonamide
  • 1-Butyl-3-(p-hydroxymethylphenyl)sulfonylurea
  • 1-butyl-3-[4-(hydroxymethyl)phenyl]sulfonylurea
  • 3-butyl-1-[4-(hydroxymethyl)benzenesulfonyl]urea
  • 4-hydroxy-tolbutamide
  • Tolbutamide Impurity 4
  • US9333197, 4-Hydroxytolbutamide
  • 4-Hydroxytolbutamide, >=98% (HPLC)
  • 1-butyl-3-[4-(hydroxymethyl)phenyl]sulfonyl-urea
  • 3-butyl-1-{[4-(hydroxymethyl)benzene]sulfonyl}urea
  • 1-Butyl-3-(P-hydroxymethyl) phenyl sulfonylurea
  • N-(Butylcarbamoyl)-4-(hydroxymethyl)benzene-1-sulfonamide
Show all 26 synonyms
  • 4-Hydroxytolbutamide,N-(Butylaminocarbonyl)-4-hydroxymethylbenzenesulfonamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
286.35 g/molcalc.
Exact mass
286.0987 Dacalc.
LogP (octanol/water)
0.97calc.
Topological polar surface area
95.5 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
19calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.42calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Hydroxytolbutamide suppliers

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Hydroxytolbutamide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hydroxytolbutamide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Hydroxytolbutamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hydroxytolbutamide, based on the data on this page

What is Hydroxytolbutamide?

4-hydroxytolbutamide is a urea that consists of 1-butylurea having a 4-hydroxymethylbenzenesulfonyl group attached at the 3-position. It has a role as a metabolite. It is a member of benzyl alcohols, a sulfonamide and a member of ureas.

What is the CAS number of Hydroxytolbutamide?

The CAS registry number of Hydroxytolbutamide is 5719-85-7. Other or deprecated CAS numbers: 1185112-19-9.

What is the molecular formula and weight of Hydroxytolbutamide?

The molecular formula of Hydroxytolbutamide is C12H18N2O4S and its molar mass is 286.35 g/mol.

What is Hydroxytolbutamide used for?

Known uses and roles of Hydroxytolbutamide include metabolite.

Is Hydroxytolbutamide hazardous?

No GHS hazard classification for Hydroxytolbutamide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Hydroxytolbutamide?

Hydroxytolbutamide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hydroxytolbutamide?

Post a free request on CompoundList and suppliers of Hydroxytolbutamide will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Hydroxytolbutamide?

Suppliers quote Hydroxytolbutamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hydroxytolbutamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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