Ilaprazole
Also known as noltec, ilaprazol, 2-((RS)-((4-Methoxy-3-methylpyridin-2-yl)methyl)sulfinyl)-5-(1H-pyrrol-1-yl)-1H-benzimidazole
Key facts
What buyers check first
- CAS number
- 172152-36-2
- Formula
- C19H18N4O2S
- Molar mass
- 366.45 g/mol
- HS code
- 293339
- Category
- Screening compounds
What is Ilaprazole?
Plain description, key identifiers and synonyms
Ilaprazole is a sulfoxide and a member of benzimidazoles.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2-[(4-methoxy-3-methyl-2-pyridinyl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
- CAS number
- 172152-36-2 CAS number cross-checked
- Molecular formula
- C19H18N4O2S
- UNII
- 776Q6XX45J
- MDL number
- MFCD00942538
- InChIKey
- HRRXCXABAPSOCP-UHFFFAOYSA-N
- InChI
- InChI=1S/C19H18N4O2S/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23/h3-11H,12H2,1-2H3,(H,21,22)
- SMILES (canonical and isomeric)
- CC1=C(C=CN=C1CS(=O)C2=NC3=C(N2)C=C(C=C3)N4C=CC=C4)OC
Synonyms
- noltec
- ilaprazol
- 2-((RS)-((4-Methoxy-3-methylpyridin-2-yl)methyl)sulfinyl)-5-(1H-pyrrol-1-yl)-1H-benzimidazole
- ilaprazolum
- 2-((4-methoxy-3-methylpyridin-2-yl)methanesulfinyl)-5-(1H-pyrrol-1-yl)-1H-1,3-benzodiazole
- Iy 81149
- 2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
- 2-(((4-methoxy-3-methylpyridin-2-yl)methyl)sulfinyl)-6-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole
- 2-[(4-Methoxy-3-methyl-pyridin-2-yl)methylsulfinyl]-5-pyrrol-1-yl-3H-benzoimidazole
- Ilaprazole (INN)
- Aldenon
- 2-[(4-methoxy-3-methyl-2-pyridinyl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
- Ilaprazole?
- Ilaprazole (Standard)
- 2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-1H-Benzimidazole
- 2-[(4-methoxy-3-methyl-2-pyridyl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
- 1H-Benzimidazole,2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-5-(1H-pyrrol-1-yl)- (9CI)
- 2-[(4-methoxy-3-methyl-pyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1h-benzoimidazole
- 2-[[(4-Methoxy-3-methyl-2-pyridyl)methyl]sulfinyl]-6-(1-pyrrolyl)benzimidazole
- 2-{[(4-methoxy-3-methylpyridin-2-yl)methyl]sulfinyl}-5-(1H-pyrrol-1-yl)-1H-benzimidazole
- 2-[(4-Methoxy-3-methylpyridin-2-yl)methanesulfinyl]-6-(1H-pyrrol-1-yl)-1H-1,3-benzimidazole
- Ilaprazole, 2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-1H-benzimidazole
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 366.45 g/molcalc.Computed value |
|---|---|
| Exact mass | 366.115 Dacalc.Computed value |
| LogP (octanol/water) | 3.37calc.Computed value |
| Topological polar surface area | 72.8 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 4calc.Computed value |
| Rotatable bonds | 5calc.Computed value |
| Heavy atoms | 26calc.Computed value |
| Rings | 4calc.Computed value |
| Aromatic rings | 4calc.Computed value |
| Fraction sp3 carbons | 0.16calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 1calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Ilaprazole suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- India, HyderabadUnclaimed profileIlaprazoleGrade, purity and minimum order on requestPrice on request
- China, Hangzhou ManufacturerUnclaimed profileIlaprazoleGrade, purity and minimum order on requestPrice on request
- Price on request
- China, ShanghaiUnclaimed profileIlaprazoleGrade, purity and minimum order on requestPrice on request
- China, Zhuhai ManufacturerUnclaimed profileIlaprazoleGrade, purity and minimum order on requestPrice on request
- Price on request
- China, Shijiazhuang ManufacturerUnclaimed profileIlaprazoleGrade, purity and minimum order on requestPrice on request
- Price on request
- China, Jinan ManufacturerUnclaimed profileIlaprazoleGrade, purity and minimum order on requestPrice on request
- India ManufacturerUnclaimed profileIlaprazoleGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
17 suppliers in 3 countries
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Ilaprazole price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Roles
- anti-ulcer drug
- pharmaceutical
Pharmacology
Ilaprazole is a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. A weak base, ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Ilaprazole is traded under.
Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…
- Germany14.2%
- United States12.8%
- Brazil10.1%
* Partner reported figures, a lower bound.
The HS code shown for Ilaprazole is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Ilaprazole, based on the data on this page
What is Ilaprazole?
What is the CAS number of Ilaprazole?
What is the molecular formula and weight of Ilaprazole?
What is Ilaprazole used for?
Is Ilaprazole hazardous?
What is the HS code of Ilaprazole?
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Where can I buy Ilaprazole in India?
What is the price of Ilaprazole?
Guides for buyers
Practical guides that help when you source, ship or handle Ilaprazole
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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