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Peptides

Insulin

Also known as Endopancrine, Decurvon, Dermulin

CAS 9004-10-8Formula C256H381N65O77S6Molar mass 5,793.64 g/molEC 232-672-8
12 suppliers listed
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Insulin chemical structure, C256H381N65O77S6, CAS 9004-10-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
9004-10-8
Formula
C256H381N65O77S6
Appearance
Colorless or almost colorless if containing not more than 100 usp units/ml, straw-colore…
Solubility
READILY SOL IN DILUTE ACIDS, SOL IN WATER
HS code
293712
Category
Peptides
Illustrative photo, colourless crystals in an open fibre drum in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Insulin?

Plain description, key identifiers and synonyms

Therapeutic Insulin is a synthetic or animal-derived form of insulin used in the treatment of diabetes mellitus. Therapeutic insulin is formulated to be short-, intermediate- and long-acting in order to individualize an insulin regimen according to individual differences in glucose and insulin metabolism. Therapeutic insulin may be derived from porcine, bovine or recombinant sources. Endogenous human insulin, a pancreatic hormone composed of two polypeptide chains, is important for the normal metabolism of carbohydrates, proteins and fats and has anabolic effects on many types of tissues.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4S)-4-[[2-[[(1R,6R,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,42R,47R,50S,53S,56S,59S,62S,65S,68S,71S,74S,77S,80S,83S,88R)-88-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[(2-aminoacetyl)amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amino]-6-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-3-amino-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-oxopropanoyl]amino]-5-oxopentanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-4-methylpentanoyl]amino]-47-[[(1S)-3-amino-1-carboxy-3-oxopropyl]carbamoyl]-53-(2-amino-2-oxoethyl)-62-(3-amino-3-oxopropyl)-77-[(2R)-butan-2-yl]-24,56-bis(2-carboxyethyl)-83-[(1S)-1-hydroxyethyl]-12,71,80-tris(hydroxymethyl)-33,50,65-tris[(4-hydroxyphenyl)methyl]-15-(1H-imidazol-4-ylmethyl)-27-methyl-18,30,36,59,68-pentakis(2-methylpropyl)-7,10,13,16,19,22,25,28,31,34,37,40,49,52,55,58,61,64,67,70,73,76,79,82,85,87-hexacosaoxo-21,39-di(propan-2-yl)-3,4,44,45,90,91-hexathia-8,11,14,17,20,23,26,29...
CAS number
9004-10-8 CAS number cross-checked
EC number
232-672-8
Molecular formula
C256H381N65O77S6
InChIKey
YAJCHEVQCOHZDC-QMMNLEPNSA-N
InChI
InChI=1S/C256H381N65O77S6/c1-29-130(23)202(311-190(337)103-258)250(391)315-200(128(19)20)246(387)286-158(75-82-197(347)348)216(357)281-154(70-77-186(261)333)220(361)306-181-115-402-403-116-182-241(382)303-176(110-323)238(379)293-161(88-122(7)8)224(365)294-167(95-139-53-61-145(328)62-54-139)227(368)282-153(69-76-185(260)332)217(358)289-160(87-121(5)6)222(363)283-157(74-81-196(345)346)219(360)301-173(101-188(263)335)233(374)297-169(97-141-57-65-147(330)66-58-141)230(371)307-180(240(381)302-174(254(395)396)102-189(264)336)114-401-400-113-179(213(354)272-106-191(338)277-152(72-79-194(341)342)215(356)280-150(51-42-84-270-256(266)267)211(352)271-107-192(339)278-165(93-137-46-36-32-37-47-137)226(367)296-166(94-138-48-38-33-39-49-138)229(370)298-170(98-142-59-67-148(331)68-60-142)236(377)318-205(134(27)326)253(394)321-85-43-52-184(321)244(385)284-151(50-40-41-83-257)221(362)319-206(135(28)327)255(397)398)309-247(388)199(127(17)18)314-234(375)163(90-124(11)12)291-228(369)168(96-140-55-63-146(329)64-56-140)295-223(364)159(86-120(3)4)288-209(350)132(25)276-214(355)156(73-80-195(343)344)285-245(386)198(126(15)16)313-235(376)164(91-125(13)14)292-232(373)172(100-144-105-269-119-275-144)300-237(378)175(109-322)279-193(340)108-273-212(353)178(112-399-404-117-183(308-242(181)383)243(384)317-204(133(26)325)251(392)304-177(111-324)239(380)316-203(131(24)30-2)249(390)310-182)305-225(366)162(89-123(9)10)290-231(372)171(99-143-104-268-118-274-143)299-218(359)155(71-78-187(262)334)287-252(393)207(208(265)349)320-248(389)201(129(21)22)312-210(351)149(259)92-136-44-34-31-35-45-136/h31-39,44-49,53-68,104-105,118-135,149-184,198-207,322-331H,29-30,40-43,50-52,69-103,106-117,257-259H2,1-28H3,(H2,260,332)(H2,261,333)(H2,262,334)(H2,263,335)(H2,264,336)(H2,265,349)(H,268,274)(H,269,275)(H,271,352)(H,272,354)(H,273,353)(H,276,355)(H,277,338)(H,278,339)(H,279,340)(H,280,356)(H,281,357)(H,282,368)(H,283,363)(H,284,385)(H,285,386)(H,286,387)(H,287,393)(H,288,350)(H,289,358)(H,290,372)(H,291,369)(H,292,373)(H,293,379)(H,294,365)(H,295,364)(H,296,367)(H,297,374)(H,298,370)(H,299,359)(H,300,378)(H,301,360)(H,302,381)(H,303,382)(H,304,392)(H,305,366)(H,306,361)(H,307,371)(H,308,383)(H,309,388)(H,310,390)(H,311,337)(H,312,351)(H,313,376)(H,314,375)(H,315,391)(H,316,380)(H,317,384)(H,318,377)(H,319,362)(H,320,389)(H,341,342)(H,343,344)(H,345,346)(H,347,348)(H,395,396)(H,397,398)(H4,266,267,270)/t130-,131-,132+,133+,134+,135+,149+,150+,151+,152+,153+,154+,155+,156+,157+,158+,159+,160+,161+,162+,163+,164+,165+,166+,167+,168+,169+,170+,171+,172+,173+,174+,175+,176+,177+,178+,179+,180+,181+,182-,183+,184+,198+,199+,200+,201+,202+,203+,204+,205+,206+,207+/m1/s1
Canonical SMILES
CCC(C)C(NC(=O)CN)C(=O)NC(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(N)=O)C(=O)NC1CSSCC2NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CSSCC(NC(=O)C(CC(C)C)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(NC(=O)C(N)Cc3ccccc3)C(C)C)C(N)=O)C(=O)NCC(=O)NC(CO)C(=O)NC(Cc3c[nH]cn3)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(Cc3ccccc3)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(C(=O)N3CCCC3C(=O)NC(CCCCN)C(=O)NC(C(=O)O)C(C)O)C(C)O)CSSCC(C(=O)NC(CC(N)=O)C(=O)O)NC(=O)C(Cc3ccc(O)cc3)NC(=O)C(CC(N)=O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(Cc3ccc(O)cc3)NC(=O)C(CC(C)C)NC(=O)C(CO)NC2=O)NC1=O)C(C)C
Isomeric SMILES
CC[C@@H](C)[C@H]1C(=O)N[C@@H]2CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CO)CC(C)C)CC3=CC=C(C=C3)O)CCC(=O)N)CC(C)C)CCC(=O)O)CC(=O)N)CC4=CC=C(C=C4)O)C(=O)N[C@@H](CC(=O)N)C(=O)O)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N[C@@H](CC7=CC=C(C=C7)O)C(=O)N[C@@H]([C@H](C)O)C(=O)N8CCC[C@H]8C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@H](C)O)C(=O)O)C(C)C)CC(C)C)CC9=CC=C(C=C9)O)CC(C)C)C)CCC(=O)O)C(C)C)CC(C)C)CC2=CNC=N2)CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC2=CNC=N2)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](C(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC2=CC=CC=C2)N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CO)[C@H](C)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H]([C@H](C)CC)NC(=O)CN

Synonyms

  • Endopancrine
  • Decurvon
  • Dermulin
  • Insular
  • Insulyl
  • Iszilin
  • Musulin
  • Iletin
  • Intesulin B
  • Insulina dalanatada
  • Insulinum dalanatum
  • AERx
  • Insulin injection
  • Insulina iniettabile neutra
  • Insulini injectio neutralis
  • Injectable insulini neutrale
  • Inyectable neutro de insulina
  • Solute neutre injectable d'insuline
  • HMR 4006
  • Insuman infusat
  • Soluble Insulin
  • Velosulin br
  • Ins humulin r
  • Actrapid MC
  • Insulin, Soluble
Show all 38 synonyms
  • Velosulin br human
  • Chain, Insulin B
  • Recombinant Insulin
  • Therapeutic Insulin
  • Insulin bovine insulin
  • Actrapid HM
  • NN 1953
  • Humilin
  • insulin-human
  • Dal-insulinum
  • Insulin, dalanated
  • Imusay-131
  • Dalanated insulin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless or almost colorless if containing not more than 100 usp units/ml, straw-colored if containing 500 unitsexp.
Solubility
READILY SOL IN DILUTE ACIDS, SOL IN WATERexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
5,793.64 g/molcalc.
Exact mass
5,789.622 Dacalc.
LogP (octanol/water)
-19.76calc.
Topological polar surface area
2,299 Ųcalc.
Hydrogen bond donors
78calc.
Hydrogen bond acceptors
83calc.
Rotatable bonds
125calc.
Heavy atoms
404calc.
Rings
12calc.
Aromatic rings
9calc.
Fraction sp3 carbons
0.57calc.
Formal charge
0calc.
Stereocentres
52calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Insulin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 12 suppliers
12 of 12 offers
  • Virtu Pharmako (Zhejiang) Co., Ltd.
    China, Jiaxing ManufacturerUnclaimed profile
    InsulinGrade Pharma (USP)
    Price on request
    View
  • Amphastar France Pharmaceuticals
    France, Eragny-Sur-Epte ManufacturerUnclaimed profile
    Recombinant InsulinGrade, purity and minimum order on request
    Price on request
    View
  • Eli Lilly and Company
    United States, IndianapolisUnclaimed profile
    InsulinGrade, purity and minimum order on request
    Price on request
    View
  • Novo Nordisk A/S
    Denmark, Bagsvaerd ManufacturerUnclaimed profile
    InsulinGrade, purity and minimum order on request
    Price on request
    View
  • Biocon Biologics Limited
    India, Bengaluru ManufacturerUnclaimed profile
    InsulinGrade, purity and minimum order on request
    Price on request
    View
  • Sigma-Aldrich
    United States, Saint LouisUnclaimed profile
    InsulinGrade, purity and minimum order on request
    Price on request
    View
  • Alfa Chemistry
    United States, HolbrookUnclaimed profile
    InsulinGrade, purity and minimum order on request
    Price on request
    View
  • BenchChem
    United States, AustinUnclaimed profile
    InsulinGrade, purity and minimum order on request
    Price on request
    View
  • BOC Sciences
    United States, New YorkUnclaimed profile
    InsulinGrade, purity and minimum order on request
    Price on request
    View
  • EvitaChem
    China, BeijingUnclaimed profile
    InsulinGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

12 suppliers in 5 countries

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Insulin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Pharmacological actions

  • Hypoglycemic Agents

Pharmacology

Insulin is a pancreatic hormone that plays an essential role in regulation of blood glucose as well as lipid and carbohydrate metabolism. Both natural and recombinant forms of insulin are used therapeutically to treat type 1 diabetes. While insulin itself is not hepatotoxic and has not been linked to serum enzyme elevations or instances of clinically apparent liver injury, high doses including overdoses of insulin and glucose can result in hepatic glycogenosis and serum aminotransferase elevations.

How it is made

Extraction of the pancreas of slaughtered animals with acidified dilute alcohol, followed by precipitation with absolute alcohol, redissolution, precipitation with zinc chloride, & redissolution in water

Synthesis of human insulin: katsoyamis et al, j am chem soc 88, 164, 166 (1966), ruttenberg, science 177, 623 (1972) (from porcine insulin). ... Approaches to commercial synthesis: chem & eng news 52, 19 (april 29, 1974).

By use of porcine insulin as starting material, human insulin can now be synthesized with relative ease.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Insulin is traded under.

HS 2937.12Exact HS code

Insulin and its salts

World exports in 2024
$390M
−58.1% vs 2023, imports $322M
2019 to 2024
Top exporters
  1. Denmark41.4%
  2. United States16.8%
  3. Portugal13.3%
Top importers
  1. United States29.8%
  2. Italy11.0%
  3. Brazil10.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Insulin is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Insulin, based on the data on this page

What is Insulin?

Therapeutic Insulin is a synthetic or animal-derived form of insulin used in the treatment of diabetes mellitus. Therapeutic insulin is formulated to be short-, intermediate- and long-acting in order to individualize an insulin regimen according to individual differences in glucose and insulin metabolism.

What is the CAS number of Insulin?

The CAS registry number of Insulin is 9004-10-8.

What is the molecular formula and weight of Insulin?

The molecular formula of Insulin is C256H381N65O77S6 and its molar mass is 5,793.64 g/mol.

What is Insulin used for?

Use classes: Animal Drugs.

Is Insulin hazardous?

No GHS hazard classification for Insulin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Insulin?

Insulin is usually classified under HS code 293712 (Insulin and its salts). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Insulin?

CompoundList lists 12 suppliers of Insulin in United States, China, Denmark, France and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Insulin in India?

1 supplier in India list Insulin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Insulin?

Suppliers quote Insulin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Insulin

Get quotes for Insulin

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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