Ipamorelin
Also known as Aib-His-D-2-Nal-D-Phe-Lys-NH2, NNC 26-0161, Aib-His-2Nal-Phe-Lys-NH2
Key facts
What buyers check first
What is Ipamorelin?
Plain description, key identifiers and synonyms
Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. Besides its presence in the brain, GHSR can also be found in the gastrointestinal tract, heart, lung, liver, kidney, pancreas, adipose tissue and immune cells. Unlike other GH releasing peptides, ipamorelin only stimulates GH release in a manner very similar to that of growth hormone releasing hormone.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
- CAS number
- 170851-70-4 CAS number cross-checked
- Molecular formula
- C38H49N9O5
- UNII
- Y9M3S784Z6
- MDL number
- MFCD02179658
- InChIKey
- NEHWBYHLYZGBNO-BVEPWEIPSA-N
- InChI
- InChI=1S/C38H49N9O5/c1-38(2,41)37(52)47-32(21-28-22-42-23-43-28)36(51)46-31(20-25-15-16-26-12-6-7-13-27(26)18-25)35(50)45-30(19-24-10-4-3-5-11-24)34(49)44-29(33(40)48)14-8-9-17-39/h3-7,10-13,15-16,18,22-23,29-32H,8-9,14,17,19-21,39,41H2,1-2H3,(H2,40,48)(H,42,43)(H,44,49)(H,45,50)(H,46,51)(H,47,52)/t29-,30+,31+,32-/m0/s1
- Canonical SMILES
- CC(C)(N)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCCN)C(N)=O
- Isomeric SMILES
- CC(C)(C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@H](CC2=CC3=CC=CC=C3C=C2)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCCCN)C(=O)N)N
Synonyms
- Aib-His-D-2-Nal-D-Phe-Lys-NH2
- NNC 26-0161
- Aib-His-2Nal-Phe-Lys-NH2
- 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide
- Ipamorelin acetate
- 2-Methylalanyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-D-phenylalanyl-L-lysinamide
- Ipamorelina
- Ipamoreline
- 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide.
- (S)-6-amino-2-((R)-2-((R)-2-((S)-2-(2-amino-2-methylpropanamido)-3-(1H-imidazol-4-yl)propanamido)-3-(naphthalen-2-yl)propanamido)-3-phenylpropanamido)hexanamide
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 711.87 g/molcalc.Computed value |
|---|---|
| Exact mass | 711.3857 Dacalc.Computed value |
| LogP (octanol/water) | 0.88calc.Computed value |
| Topological polar surface area | 240.2 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 8calc.Computed value |
| Hydrogen bond acceptors | 8calc.Computed value |
| Rotatable bonds | 19calc.Computed value |
| Heavy atoms | 52calc.Computed value |
| Rings | 4calc.Computed value |
| Aromatic rings | 4calc.Computed value |
| Fraction sp3 carbons | 0.37calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 4calc.Computed value |
| Lipinski rule of five | Fails (2 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C(CCc1cnc[nH]1)NC(Cc1ccc2ccccc2c1)C(=O)NCCc1ccccc1
4 rings, 33 atoms.
1 other chemical share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Ipamorelin suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- ChinaUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
- China, ChangzhouUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
- China, Shanghai ManufacturerUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
- China, Leshan ManufacturerUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
- China, Shenzhen ManufacturerUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
- China, Qingyuan ManufacturerUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
- China, Jinhua ManufacturerUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
- United States, DavieUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
- China, Qingdao ManufacturerUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
- United States, Louisville ManufacturerUnclaimed profileIpamorelinGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
15 suppliers in 3 countries
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Ipamorelin price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Roles
- gastrointestinal drug
- pharmaceutical
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Ipamorelin is traded under.
Compounds containing an unfused imidazole ring (whether or not hydrogenated) in theโฆ
- United Kingdom13.0%
- United States7.9%
- China6.5%
* Partner reported figures, a lower bound.
The HS code shown for Ipamorelin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Ipamorelin, based on the data on this page
What is Ipamorelin?
What is the CAS number of Ipamorelin?
What is the molecular formula and weight of Ipamorelin?
What is Ipamorelin used for?
Is Ipamorelin hazardous?
What is the HS code of Ipamorelin?
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Guides for buyers
Practical guides that help when you source, ship or handle Ipamorelin
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
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