CompoundList

Ipamorelin

Also known as Aib-His-D-2-Nal-D-Phe-Lys-NH2, NNC 26-0161, Aib-His-2Nal-Phe-Lys-NH2

CAS 170851-70-4Formula C38H49N9O5Molar mass 711.87 g/mol
Ipamorelin chemical structure, C38H49N9O5, CAS 170851-70-4
2D chemical structure

Key facts

What buyers check first

CAS number
170851-70-4
Formula
C38H49N9O5
Molar mass
711.87 g/mol
HS code
293329
Category
Peptides

What is Ipamorelin?

Plain description, key identifiers and synonyms

Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. Besides its presence in the brain, GHSR can also be found in the gastrointestinal tract, heart, lung, liver, kidney, pancreas, adipose tissue and immune cells. Unlike other GH releasing peptides, ipamorelin only stimulates GH release in a manner very similar to that of growth hormone releasing hormone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
CAS number
170851-70-4 CAS number cross-checked
Molecular formula
C38H49N9O5
UNII
Y9M3S784Z6
MDL number
MFCD02179658
InChIKey
NEHWBYHLYZGBNO-BVEPWEIPSA-N
InChI
InChI=1S/C38H49N9O5/c1-38(2,41)37(52)47-32(21-28-22-42-23-43-28)36(51)46-31(20-25-15-16-26-12-6-7-13-27(26)18-25)35(50)45-30(19-24-10-4-3-5-11-24)34(49)44-29(33(40)48)14-8-9-17-39/h3-7,10-13,15-16,18,22-23,29-32H,8-9,14,17,19-21,39,41H2,1-2H3,(H2,40,48)(H,42,43)(H,44,49)(H,45,50)(H,46,51)(H,47,52)/t29-,30+,31+,32-/m0/s1
Canonical SMILES
CC(C)(N)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCCN)C(N)=O
Isomeric SMILES
CC(C)(C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@H](CC2=CC3=CC=CC=C3C=C2)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCCCN)C(=O)N)N

Synonyms

  • Aib-His-D-2-Nal-D-Phe-Lys-NH2
  • NNC 26-0161
  • Aib-His-2Nal-Phe-Lys-NH2
  • 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide
  • Ipamorelin acetate
  • 2-Methylalanyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-D-phenylalanyl-L-lysinamide
  • Ipamorelina
  • Ipamoreline
  • 2-Methylalanyl-L-histidyl-3-(2-naphthyl)-D-alanyl-D-phenylalanyl-L-lysinamide.
  • (S)-6-amino-2-((R)-2-((R)-2-((S)-2-(2-amino-2-methylpropanamido)-3-(1H-imidazol-4-yl)propanamido)-3-(naphthalen-2-yl)propanamido)-3-phenylpropanamido)hexanamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
711.87 g/molcalc.
Exact mass
711.3857 Dacalc.
LogP (octanol/water)
0.88calc.
Topological polar surface area
240.2 ร…ยฒcalc.
Hydrogen bond donors
8calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
19calc.
Heavy atoms
52calc.
Rings
4calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.37calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CCc1cnc[nH]1)NC(Cc1ccc2ccccc2c1)C(=O)NCCc1ccccc1

O=C(CCc1cnc[nH]1)NC(Cc1ccc2ccccc2c1)C(=O)NCCc1ccccc1

4 rings, 33 atoms.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Ipamorelin suppliers

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Ipamorelin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • gastrointestinal drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ipamorelin is traded under.

HS 2933.29Indicative HS code

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in theโ€ฆ

World exports in 2024
$1.43B
โˆ’7.6% vs 2023, imports $1.47B
2019 to 2024
Top exporters
  1. China28.1%
  2. France * partner reported12.7%
  3. India * partner reported10.3%
Top importers
  1. United Kingdom13.0%
  2. United States7.9%
  3. China6.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ipamorelin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ipamorelin, based on the data on this page

What is Ipamorelin?

Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland.

What is the CAS number of Ipamorelin?

The CAS registry number of Ipamorelin is 170851-70-4.

What is the molecular formula and weight of Ipamorelin?

The molecular formula of Ipamorelin is C38H49N9O5 and its molar mass is 711.87 g/mol.

What is Ipamorelin used for?

Known uses and roles of Ipamorelin include gastrointestinal drug and pharmaceutical.

Is Ipamorelin hazardous?

No GHS hazard classification for Ipamorelin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Ipamorelin?

Ipamorelin is usually classified under HS code 293329 (Compounds containing an unfused imidazole ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ipamorelin?

CompoundList lists 15 suppliers of Ipamorelin in China, United States and Canada. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ipamorelin?

Suppliers quote Ipamorelin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ipamorelin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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