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Synthesis reagents

Iproplatin

Also known as CHIP organoplatinum compound, Iproplatine, Iproplatino

CAS 62928-11-4Formula C6H20Cl2N2O2Pt-4Molar mass 418.22 g/mol
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Iproplatin chemical structure, C6H20Cl2N2O2Pt-4, CAS 62928-11-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
62928-11-4
Formula
C6H20Cl2N2O2Pt-4
Molar mass
418.22 g/mol
HS code
284390
Category
Synthesis reagents

What is Iproplatin?

Plain description, key identifiers and synonyms

Iproplatin is a synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and forms DNA crosslinks and platinum-DNA adducts, resulting in DNA replication failure and cell death. Although less prone to glutathione inactivation compared to cisplatin, resistance to this agent has been observed in vitro due to repair of platination damage by tumor cells. (NCI04)

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
platinum, bis(propan-2-amine), dichloride, dihydroxide
CAS number
62928-11-4Other or deprecated CAS: 83291-20-7
Molecular formula
C6H20Cl2N2O2Pt-4
UNII
5R9F9NE9Z2
InChIKey
AGFPKKCNKJRESC-UHFFFAOYSA-J
InChI
InChI=1S/2C3H9N.2ClH.2H2O.Pt/c2*1-3(2)4;;;;;/h2*3H,4H2,1-2H3;2*1H;2*1H2;/p-4
SMILES (canonical and isomeric)
CC(C)N.CC(C)N.[OH-].[OH-].[Cl-].[Cl-].[Pt]

Synonyms

  • CHIP organoplatinum compound
  • Iproplatine
  • Iproplatino
  • Iproplatinum
  • dichlorobis(isopropylamine)dihydroxyplatinum IV
  • Diisopropylammine-trans-dihydroxymalonatoplatinum(IV)
  • Platinum, dichlorodihydroxybis(2-propanamine)-, (oc-6-33)-
  • Platinum, dichlorodihydroxybis(2-propanamine)-, (OC-6-33)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
418.22 g/molcalc.
Exact mass
417.0572 Dacalc.
LogP (octanol/water)
-5.64calc.
Topological polar surface area
112 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
0calc.
Heavy atoms
13calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
-4calc.
Stereocentres
0calc.
Components
7calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Iproplatin suppliers

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Iproplatin price

Indicative price range per kg from live supplier offers

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Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antineoplastic Agents
  • Cross-Linking Reagents

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Iproplatin is traded under.

HS 2843.90Indicative HS code

Amalgams

World exports in 2024
$5.76B
−33.2% vs 2023, imports $3.61B
2019 to 2024
Top exporters
  1. Germany36.9%
  2. Japan23.5%
  3. United States13.0%
Top importers
  1. India * partner reported23.1%
  2. Mexico11.6%
  3. Germany10.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Iproplatin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Iproplatin, based on the data on this page

What is Iproplatin?

Iproplatin is a synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and forms DNA crosslinks and platinum-DNA adducts, resulting in DNA replication failure and cell death.

What is the CAS number of Iproplatin?

The CAS registry number of Iproplatin is 62928-11-4. Other or deprecated CAS numbers: 83291-20-7.

What is the molecular formula and weight of Iproplatin?

The molecular formula of Iproplatin is C6H20Cl2N2O2Pt-4 and its molar mass is 418.22 g/mol.

What is Iproplatin used for?

Known uses and roles of Iproplatin include synthesis reagents in research and laboratory, antineoplastic agents and cross-linking reagents.

Is Iproplatin hazardous?

No GHS hazard classification for Iproplatin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Iproplatin?

Iproplatin is usually classified under HS code 284390 (Colloidal precious metals, inorganic or organic compounds of precious metals, whether or…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Iproplatin?

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What is the price of Iproplatin?

Suppliers quote Iproplatin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Iproplatin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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