CompoundList
Sign in
Screening compounds

Kpt-330, (E)-

Also known as trans-Selinexor, Selinexor, trans, 2-Propenoic acid, 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-, 2-(2-pyrazinyl)hydrazide, (2E)-

CAS 1421923-86-5Formula C17H11F6N7OMolar mass 443.31 g/molEC 868-446-6
GHS signal word: Warning. Pictograms: Harmful or irritant
Get quotes Safety data
Kpt-330, (E)- chemical structure, C17H11F6N7O, CAS 1421923-86-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1421923-86-5
Formula
C17H11F6N7O
Molar mass
443.31 g/mol
EC number
868-446-6
HS code
293399
Category
Screening compounds

What is Kpt-330, (E)-?

Plain description, key identifiers and synonyms

Kpt-330, (E)- is a chemical substance with the molecular formula C17H11F6N7O and a molar mass of 443.31 g/mol. Its CAS registry number is 1421923-86-5. The IUPAC name is (E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide
CAS number
1421923-86-5
EC number
868-446-6
Molecular formula
C17H11F6N7O
UNII
MVY2AE6R24
MDL number
MFCD28559396
InChIKey
DEVSOMFAQLZNKR-DAFODLJHSA-N
InChI
InChI=1S/C17H11F6N7O/c18-16(19,20)11-5-10(6-12(7-11)17(21,22)23)15-26-9-30(29-15)4-1-14(31)28-27-13-8-24-2-3-25-13/h1-9H,(H,25,27)(H,28,31)/b4-1+
Canonical SMILES
O=C(C=Cn1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)NNc1cnccn1
Isomeric SMILES
C1=CN=C(C=N1)NNC(=O)/C=C/N2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F

Synonyms

  • trans-Selinexor
  • Selinexor, trans
  • 2-Propenoic acid, 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-, 2-(2-pyrazinyl)hydrazide, (2E)-
  • 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2E)-
  • (E)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide
  • Selinexor trans-isomer
  • (E)-Selinexor
  • (E)-KPT330
  • (E)-kpt-330
  • (E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide
  • KPT330Selinexor
  • 1421923-86-5 (E-isomer)
  • (E)-RN
  • (E)-KPT330(E)-RN
  • KPT-330 (E)
  • KPT330,(E)-
  • O=C(NNC1=NC=CN=C1)/C=C/N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
  • (2E)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-N'-(pyrazin-2-yl)prop-2-enehydrazide
  • (E)-3-(3-(3,5-bis(trifluoromethyl) phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide
  • (E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-yl-prop-2-enehydrazide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
443.31 g/molcalc.
Exact mass
443.0929 Dacalc.
LogP (octanol/water)
3.39calc.
Topological polar surface area
97.62 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
5calc.
Heavy atoms
31calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.12calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(C=Cn1cnc(-c2ccccc2)n1)NNc1cnccn1

O=C(C=Cn1cnc(-c2ccccc2)n1)NNc1cnccn1

3 rings, 23 atoms.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Kpt-330, (E)- suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

No supplier listings yet

Post one free request and suppliers who make or trade Kpt-330, (E)- can send you quotes. Your contact details stay private until you accept a quote.

Request quotesSell this chemical

Kpt-330, (E)- price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Kpt-330, (E)- is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Kpt-330, (E)- is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Kpt-330, (E)-, based on the data on this page

What is Kpt-330, (E)-?

Kpt-330, (E)- is a chemical substance with the molecular formula C17H11F6N7O and a molar mass of 443.31 g/mol. Its CAS registry number is 1421923-86-5. The IUPAC name is (E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide.

What is the CAS number of Kpt-330, (E)-?

The CAS registry number of Kpt-330, (E)- is 1421923-86-5.

What is the molecular formula and weight of Kpt-330, (E)-?

The molecular formula of Kpt-330, (E)- is C17H11F6N7O and its molar mass is 443.31 g/mol.

What is Kpt-330, (E)- used for?

Known uses and roles of Kpt-330, (E)- include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Kpt-330, (E)- hazardous?

Kpt-330, (E)- carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Kpt-330, (E)-?

Kpt-330, (E)- is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Kpt-330, (E)-?

Post a free request on CompoundList and suppliers of Kpt-330, (E)- will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Kpt-330, (E)-?

Suppliers quote Kpt-330, (E)- on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Kpt-330, (E)-

Get quotes for Kpt-330, (E)-

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Kpt-330, (E)-
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Kpt-330, (E)- with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/kpt-330-e-1421923-86-5" title="Kpt-330, (E)- structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Screening compounds or HS code 293399

Price on request
Free quotes, contact stays private
Get quotes