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Oncology and immunology drugs

Lenalidomide

Also known as Revlimid, Revimid, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

CAS 191732-72-6Formula C13H13N3O3Molar mass 259.27 g/molEC 691-297-1
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant, Serious health hazard 183 suppliers listed Drug substance
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Lenalidomide chemical structure, C13H13N3O3, CAS 191732-72-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
191732-72-6
Formula
C13H13N3O3
Appearance
Off-white to pale-yellow solid powder
Solubility
Soluble in organic solvent/water mixtures and buffered aqueous solutions . more soluble…
HS code
293379
Category
Oncology and immunology drugs
Illustrative photo, off-white crystalline powder with an amber glass bottle on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Lenalidomide?

Plain description, key identifiers and synonyms

Lenalidomide is a dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha. It has a role as an antineoplastic agent, an angiogenesis inhibitor and an immunomodulator. It is a member of isoindoles, an aromatic amine, a dicarboximide and a member of piperidones.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
CAS number
191732-72-6 CAS number cross-checked
EC number
691-297-1
Molecular formula
C13H13N3O3
UNII
F0P408N6V4
MDL number
MFCD07772307
InChIKey
GOTYRUGSSMKFNF-UHFFFAOYSA-N
InChI
InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
SMILES (canonical and isomeric)
C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N

Synonyms

  • Revlimid
  • Revimid
  • 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
  • CDC 501
  • 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-
  • 3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
  • Lenalidomida
  • 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline
  • 3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione
  • 4-amino-2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-2,3-dihydro-1H-isoindol-1-one
  • IMiD3 cpd
  • lenalidomidum
  • Lenalidomide (CC-5013)
  • 3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
  • CC 5013
  • Lenadoamide
  • ENMD 0997
  • Revlimid (TN)
  • 3-(4-amino-1,3-dihydro-1-oxo-2h-isoindol-2-yl)-2,6-piperidinedione
  • 2, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-
  • 3-(4-Amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
  • Lenalidomide?
  • Revimid,
  • ENMD-0997
  • IMID-5013
Show all 29 synonyms
  • Lenalidomide (Standard)
  • Revlimid (TN) (Celgene)
  • CC-5013 (Lenalidomide)
  • 1-Benzyl-4-piperidinone Oxi

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Off-white to pale-yellow solid powderexp.
Solubility
Soluble in organic solvent/water mixtures and buffered aqueous solutions . more soluble in organic solvents and low pH solutions. Solubility was lower in less acidic buffers, ranging from 0.4 to 0.5 mg/mLexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
259.27 g/molcalc.
Exact mass
259.0957 Dacalc.
LogP (octanol/water)
0.03calc.
Topological polar surface area
92.5 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
1calc.
Heavy atoms
19calc.
Rings
3calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.31calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCC(N2Cc3ccccc3C2=O)C(=O)N1

O=C1CCC(N2Cc3ccccc3C2=O)C(=O)N1

3 rings, 18 atoms, the 3-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione ring system.

1,268 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H332Harmful if inhaled.
  • H360May damage fertility or the unborn child.
  • H372Causes damage to organs through prolonged or repeated exposure.
Precautionary statements (19)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lenalidomide suppliers

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All 183 suppliers
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Where suppliers are based

183 suppliers in 21 countries

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Lenalidomide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Angiogenesis Inhibitors, Immunologic Factors.

Industries and functions

Pharmacological actions

  • Angiogenesis Inhibitors
  • Immunologic Factors

Roles

  • analgesic
  • angiogenesis inhibitor
  • anti-HIV agent
  • anti-anaemic agent
  • antifibrotic agent
  • antimicrobial agent
  • antineoplastic agent
  • antiviral agent
  • immunomodulator
  • pharmaceutical

Pharmacology

Lenalidomide is a Thalidomide Analog.

How it is made

Preparation: G. W. Muller et al., United States of America patent 5635517 (1997 to Celgene).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lenalidomide is traded under.

HS 2933.79Indicative HS code

Lactams, other lactams

World exports in 2024
$16.2B
−64.4% vs 2023, imports $15.4B
2019 to 2024
Top exporters
  1. Ireland37.0%
  2. France * partner reported15.6%
  3. Spain11.3%
Top importers
  1. Germany27.8%
  2. Ireland18.9%
  3. Panama * partner reported12.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Lenalidomide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lenalidomide, based on the data on this page

What is Lenalidomide?

Lenalidomide is a dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha. It has a role as an antineoplastic agent, an angiogenesis inhibitor and an immunomodulator.

What is the CAS number of Lenalidomide?

The CAS registry number of Lenalidomide is 191732-72-6.

What is the molecular formula and weight of Lenalidomide?

The molecular formula of Lenalidomide is C13H13N3O3 and its molar mass is 259.27 g/mol.

What is Lenalidomide used for?

Angiogenesis Inhibitors, Immunologic Factors.

Is Lenalidomide hazardous?

Lenalidomide carries the GHS signal word "Danger". Main hazards: toxic if swallowed, harmful if swallowed, harmful in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Lenalidomide?

Lenalidomide is usually classified under HS code 293379 (Lactams, other lactams). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lenalidomide?

CompoundList lists 183 suppliers of Lenalidomide in China, United States, India, Germany and 17 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Lenalidomide in India?

41 suppliers in India list Lenalidomide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Lenalidomide?

Suppliers quote Lenalidomide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lenalidomide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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