Licarbazepine
Also known as 10-Hydroxycarbazepine, licarbazepina, 10,11-Dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide
Key facts
What buyers check first
- CAS number
- 29331-92-8
- Formula
- C15H14N2O2
- Molar mass
- 254.29 g/mol
- EC number
- 608-350-1
- HS code
- 293399
- Category
- Heterocyclic building blocks
What is Licarbazepine?
Plain description, key identifiers and synonyms
Licarbazepine is a dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine. It has a role as an anticonvulsant, a sodium channel blocker and a drug allergen. It is a carboxamide, a dibenzoazepine and a member of ureas. It is functionally related to a carbamazepine.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
- CAS number
- 29331-92-8 CAS number cross-checked
- EC number
- 608-350-1
- Molecular formula
- C15H14N2O2
- UNII
- XFX1A5KJ3V
- MDL number
- MFCD00871817
- InChIKey
- BMPDWHIDQYTSHX-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)
- SMILES (canonical and isomeric)
- C1C(C2=CC=CC=C2N(C3=CC=CC=C31)C(=O)N)O
Synonyms
- 10-Hydroxycarbazepine
- licarbazepina
- 10,11-Dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide
- 10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
- licarbazepinum
- 10,11-MHD
- 10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
- 10,11-Dihydro-10-hydroxycarbamazepine
- 10-Hydroxycarbamazepine
- 10-OH-Carbazepine
- GP 47779
- 10,11-Dihydro-10-hydroxy Carbamazepine
- 10,11-Dihydro-10-hydroxycarbazepine
- 10-Hydroxy-10,11-dihydrocarbamazepine
- 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-
- BIA 2-005
- 10-Hydroxy-carbamazepine
- 5H-Dibenz(b,f)azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-
- 10-Hydroxy-10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic acid amide
- racemic 10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
- 10-Hydroxy-10,11-dihydro-5H-dibenz(b,f)azepine-5-carboxamide
- Licarbazepine (Standard)
- (+-)-10,11-Dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide
- 10-Hydroxy-10,11-dihydrocarbamez epine
- 10,11-Dihydro-10-hydroxycarbamazepine, analytical standard
Show all 29 synonymsShow fewer synonyms
- ( inverted exclamation markA)-10-Hydroxy-10,11-dihydro-5H-dib
- 10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5 carboxamide
- 10-Hydroxy-10,11-dihydrocarbamazepine 1.0 mg/ml in Acetonitrile
- 10,11-Dihydro-10-hydroxycarbamazepine 100 microg/mL in Acetonitrile
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 254.29 g/molcalc.Computed value |
|---|---|
| Exact mass | 254.1055 Dacalc.Computed value |
| LogP (octanol/water) | 2.49calc.Computed value |
| Topological polar surface area | 66.56 Ųcalc.Computed value |
| Hydrogen bond donors | 2calc.Computed value |
| Hydrogen bond acceptors | 2calc.Computed value |
| Rotatable bonds | 0calc.Computed value |
| Heavy atoms | 19calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.13calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 1calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
c1ccc2c(c1)CCc1ccccc1N2
3 rings, 15 atoms, the Iminodibenyl ring system.
268 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H317May cause an allergic skin reaction.
- H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H411Toxic to aquatic life with long lasting effects.
Precautionary statements (21)
- P233Keep container tightly closed.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P271Use only outdoors or in a well-ventilated area.
- P272Contaminated work clothing should not be allowed out of the workplace.
- P273Avoid release to the environment.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P284In case of inadequate ventilation wear respiratory protection.
- P301 + P317If swallowed: Get medical help.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P333 + P317If skin irritation or rash occurs: Get medical help.
- P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P391Collect spillage.
- P403Store in a well-ventilated place.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidLicarbazepine suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- India ManufacturerUnclaimed profileLicarbazepineGrade, purity and minimum order on requestPrice on request
- China, NanjingUnclaimed profileLicarbazepineGrade, purity and minimum order on requestPrice on request
- China, SuzhouUnclaimed profileLicarbazepineGrade, purity and minimum order on requestPrice on request
- United States, HauppaugeUnclaimed profileLicarbazepineGrade, purity and minimum order on requestPrice on request
- China, ShanghaiUnclaimed profileLicarbazepineGrade, purity and minimum order on requestPrice on request
- China, KunshanUnclaimed profileLicarbazepineGrade, purity and minimum order on requestPrice on request
- Canada, MontrealUnclaimed profileLicarbazepineGrade, purity and minimum order on requestPrice on request
- Czech Republic, Czech RepublicUnclaimed profileLicarbazepineGrade, purity and minimum order on requestPrice on request
- China, ChangzhouUnclaimed profileLicarbazepineGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
9 suppliers in 5 countries
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Licarbazepine price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Roles
- aetiopathogenetic role
- allergen
- anticonvulsant
- antipsychotic agent
- biophysical role
- central nervous system depressant
- central nervous system drug
- drug allergen
- membrane transport modulator
- pharmaceutical
- psychotropic drug
- sodium channel blocker
- sodium channel modulator
- tranquilizing drug
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Licarbazepine is traded under.
Heterocyclic compounds with nitrogen hetero-atom(s) only, other
- Slovenia31.7%
- Italy24.2%
- United States5.0%
* Partner reported figures, a lower bound.
The HS code shown for Licarbazepine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Licarbazepine, based on the data on this page
What is Licarbazepine?
What is the CAS number of Licarbazepine?
What is the molecular formula and weight of Licarbazepine?
What is Licarbazepine used for?
Is Licarbazepine hazardous?
What is the HS code of Licarbazepine?
Where can I buy Licarbazepine?
Where can I buy Licarbazepine in India?
What is the price of Licarbazepine?
Guides for buyers
Practical guides that help when you source, ship or handle Licarbazepine
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
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