CompoundList
Sign in
Amino acids and derivatives

Liotrix

Also known as Euthroid, Thyrolar, Liotrix (T4, T3)

CAS 8065-29-0Formula C30H21I7N2Na2O8Molar mass 1,471.81 g/mol
Get quotes Safety data
Liotrix chemical structure, C30H21I7N2Na2O8, CAS 8065-29-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
8065-29-0
Formula
C30H21I7N2Na2O8
Molar mass
1,471.81 g/mol
HS code
292250
Category
Amino acids and derivatives

What is Liotrix?

Plain description, key identifiers and synonyms

Liotrix is a phenylalanine derivative.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
disodium, (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate, (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
CAS number
8065-29-0 CAS number cross-checked
Molecular formula
C30H21I7N2Na2O8
UNII
YW8HJ0N26X
InChIKey
LKYWLLWWYBVUPP-XOCLESOZSA-L
InChI
InChI=1S/C15H11I4NO4.C15H12I3NO4.2Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);1-4,6,12,20H,5,19H2,(H,21,22);;/q;;2*+1/p-2/t2*12-;;/m00../s1
Canonical SMILES
NC(Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)[O-].NC(Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)[O-].[Na+].[Na+]
Isomeric SMILES
C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)[O-])N)I)I)O.C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)[O-])N.[Na+].[Na+]

Synonyms

  • Euthroid
  • Thyrolar
  • Liotrix (T4, T3)
  • disodium (2S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate (2S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoate
  • Combithyrex
  • Novothyral
  • disodium, (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate, (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
  • Diotroxin
  • Liothyronine Sodium and Levothyroxine Sodium
  • L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, hydrate, mixt. with O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine monosodium salt
  • L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, mixt. with O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine monosodium salt
  • Monosodium L-thyroxine hydrate mixt. with monosodium L-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
1,471.81 g/molcalc.
Exact mass
1,471.4406 Dacalc.
LogP (octanol/water)
-0.15calc.
Topological polar surface area
191.2 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
10calc.
Rotatable bonds
10calc.
Heavy atoms
49calc.
Rings
4calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
2calc.
Components
4calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Oc2ccccc2)cc1

c1ccc(Oc2ccccc2)cc1

2 rings, 13 atoms, the Diphenyl ether ring system.

9,579 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Liotrix suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

No supplier listings yet

Post one free request and suppliers who make or trade Liotrix can send you quotes. Your contact details stay private until you accept a quote.

Request quotesSell this chemical

Liotrix price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Pharmacology

Liotrix is a l-Thyroxine and l-Triiodothyronine.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Liotrix is traded under.

HS 2922.50Indicative HS code

Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function

World exports in 2024
$3.29B
−5.9% vs 2023, imports $3.19B
2019 to 2024
Top exporters
  1. China39.2%
  2. United Kingdom27.1%
  3. India * partner reported4.8%
Top importers
  1. United States20.7%
  2. Germany7.6%
  3. Italy6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Liotrix is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Liotrix, based on the data on this page

What is Liotrix?

Liotrix is a phenylalanine derivative.

What is the CAS number of Liotrix?

The CAS registry number of Liotrix is 8065-29-0.

What is the molecular formula and weight of Liotrix?

The molecular formula of Liotrix is C30H21I7N2Na2O8 and its molar mass is 1,471.81 g/mol.

Is Liotrix hazardous?

No GHS hazard classification for Liotrix is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Liotrix?

Liotrix is usually classified under HS code 292250 (Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Liotrix?

Post a free request on CompoundList and suppliers of Liotrix will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Liotrix?

Suppliers quote Liotrix on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Liotrix

Get quotes for Liotrix

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Liotrix
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Liotrix with a 3D view, its CAS number and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/liotrix-8065-29-0" title="Liotrix structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Amino acids and derivatives or HS code 292250

Price on request
Free quotes, contact stays private
Get quotes