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Screening compounds

Lisavanbulin

Also known as Lisavanbulina, Lisavanbuline, Microtubule-targeted agent bal101553

CAS 1263384-43-5Formula C26H29N9O3Molar mass 515.58 g/mol
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Lisavanbulin chemical structure, C26H29N9O3, CAS 1263384-43-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1263384-43-5
Formula
C26H29N9O3
Molar mass
515.58 g/mol
HS code
293499
Category
Screening compounds

What is Lisavanbulin?

Plain description, key identifiers and synonyms

Lisavanbulin is an orally available, highly water-soluble lysine prodrug of the synthetic small molecule BAL27862 with potential antitumor activity. Upon administration of lisavanbulin and conversion into the active form BAL27862, this agent binds to tubulin at a site distinct from the vinca-alkaloid-binding site, and prevents tubulin polymerization and destabilizes microtubules, ultimately leading to cell cycle arrest, blockage of cell division and an induction of cell death in cancer cells.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-2,6-diamino-N-[4-[2-[2-[4-(2-cyanoethylamino)-1,2,5-oxadiazol-3-yl]benzimidazol-1-yl]acetyl]phenyl]hexanamide
CAS number
1263384-43-5
Molecular formula
C26H29N9O3
UNII
5PT0QP06X5
InChIKey
NIPZLALJRAHABJ-IBGZPJMESA-N
InChI
InChI=1S/C26H29N9O3/c27-13-4-3-6-19(29)26(37)31-18-11-9-17(10-12-18)22(36)16-35-21-8-2-1-7-20(21)32-25(35)23-24(34-38-33-23)30-15-5-14-28/h1-2,7-12,19H,3-6,13,15-16,27,29H2,(H,30,34)(H,31,37)/t19-/m0/s1
Canonical SMILES
N#CCCNc1nonc1-c1nc2ccccc2n1CC(=O)c1ccc(NC(=O)C(N)CCCCN)cc1
Isomeric SMILES
C1=CC=C2C(=C1)N=C(N2CC(=O)C3=CC=C(C=C3)NC(=O)[C@H](CCCCN)N)C4=NON=C4NCCC#N

Synonyms

  • Lisavanbulina
  • Lisavanbuline
  • Microtubule-targeted agent bal101553
  • Hexanamide, 2,6-diamino-N-(4-(2-(2-(4-((2-cyanoethyl)amino)-1,2,5-oxadiazol-3-yl)-1H-benzimidazol-1-yl)acetyl)phenyl)-, (2S)-
  • (2S)-2,6-Diamino-N-(4-(2-(2-(4-((2-cyanoethyl)amino)-1,2,5-oxadiazol-3-yl)-1H-benzimidazol-1-yl)acetyl)phenyl)hexanamide
  • lisavanbulinum
  • (2S)-2,6-Diamino-N-{4-[2-(2-{4-[(2-cyanoethyl)amino]-1,2,5-oxadiazol-3-yl}-1H-benzimidazol-1-yl)acetyl]phenyl}hexanamide
  • (2S)-2,6-diamino-N-(4-(2-(2-(4-((2-cyanoethyl)amino)-1,2,5-oxadiazol-3-yl)-1H-1,3-benzodiazol-1-yl)acetyl)phenyl)hexanamide
  • WHO 10401
  • (2S)-2,6-diamino-N-[4-[2-[2-[4-(2-cyanoethylamino)-1,2,5-oxadiazol-3-yl]benzimidazol-1-yl]acetyl]phenyl]hexanamide
  • Lisavanbulin (USAN/INN)
  • BAL 101553
  • (S)-2,6-Diamino-N-(4-(2-(2-(4-((2-cyanoethyl)amino)-1,2,5-oxadiazol-3-yl)-1H-benzo[d]imidazol-1-yl)acetyl)phenyl)hexanamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
515.58 g/molcalc.
Exact mass
515.2393 Dacalc.
LogP (octanol/water)
2.69calc.
Topological polar surface area
190.8 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
10calc.
Rotatable bonds
13calc.
Heavy atoms
38calc.
Rings
4calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.31calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Cn1c(-c2cnon2)nc2ccccc21)c1ccccc1

O=C(Cn1c(-c2cnon2)nc2ccccc21)c1ccccc1

4 rings, 23 atoms.

2 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Lisavanbulin suppliers

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Where suppliers are based

1 supplier in 1 country

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Lisavanbulin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Immune Checkpoint Inhibitors

Roles

  • antineoplastic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lisavanbulin is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Lisavanbulin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lisavanbulin, based on the data on this page

What is Lisavanbulin?

Lisavanbulin is an orally available, highly water-soluble lysine prodrug of the synthetic small molecule BAL27862 with potential antitumor activity.

What is the CAS number of Lisavanbulin?

The CAS registry number of Lisavanbulin is 1263384-43-5.

What is the molecular formula and weight of Lisavanbulin?

The molecular formula of Lisavanbulin is C26H29N9O3 and its molar mass is 515.58 g/mol.

What is Lisavanbulin used for?

Known uses and roles of Lisavanbulin include building blocks in research and laboratory, screening compounds in research and laboratory, antineoplastic agent, pharmaceutical and immune checkpoint inhibitors.

Is Lisavanbulin hazardous?

No GHS hazard classification for Lisavanbulin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Lisavanbulin?

Lisavanbulin is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lisavanbulin?

CompoundList lists 1 supplier of Lisavanbulin in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Lisavanbulin?

Suppliers quote Lisavanbulin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lisavanbulin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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