Loestrin
Also known as Norlestrin, Anovlar 21, Norethindrone acetate and ethinyl estradiol
Key facts
What buyers check first
- CAS number
- 8015-12-1
- Formula
- C42H52O5
- Molar mass
- 636.87 g/mol
- HS code
- 293723
- Category
- Steroids and sterols
What is Loestrin?
Plain description, key identifiers and synonyms
Loestrin is a pharmaceutical combination.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol, [(8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate
- CAS number
- 8015-12-1 CAS number cross-checked
- Molecular formula
- C42H52O5
- InChIKey
- GEONECATAKDDLT-JDSZYESASA-N
- InChI
- InChI=1S/C22H28O3.C20H24O2/c1-4-22(25-14(2)23)12-10-20-19-7-5-15-13-16(24)6-8-17(15)18(19)9-11-21(20,22)3;1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,13,17-20H,5-12H2,2-3H3;1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t17-,18+,19+,20-,21-,22-;16-,17-,18+,19+,20+/m01/s1
- Canonical SMILES
- C#CC1(O)CCC2C3CCc4cc(O)ccc4C3CCC21C.C#CC1(OC(C)=O)CCC2C3CCC4=CC(=O)CCC4C3CCC21C
- Isomeric SMILES
- CC(=O)O[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@H]34)C)C#C.C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)O
Synonyms
- Norlestrin
- Anovlar 21
- Norethindrone acetate and ethinyl estradiol
- Controvlar
- Microgestin
- Trentovlane
- Cumorit
- Estrostep
- Etalontin
- Gynonlar
- Loveston
- Neorlest
- Primodos
- Sinovula
- Taytulla
- Gyn-Anovlar
- Lo Loestrin
- Lo Loestrin Fe
- Gynonlar 21
- Minastrin 24 Fe
- Loestrin 24 Fe
- Tri-legest 21
- Microgestin 1/20
- Aurovela 1.5/30
- Econ 30
Show all 38 synonymsShow fewer synonyms
- Hailey Fe 1/20
- Microgestin 1.5/30
- Junel 1/20
- Estrostep 21
- Junel 1.5/30
- Loestrin fe 1/20
- Loestrin 21 1/20
- Norlestrin 21 1/50
- Norlestrin 28 1/50
- Loestrin 21 1.5/30
- Norlestrin 21 2.5/50
- Ethinylestradiol and norethindrone acetate
- Norethindrone acetate and ethinylestradiol
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 636.87 g/molcalc.Computed value |
|---|---|
| Exact mass | 636.3815 Dacalc.Computed value |
| LogP (octanol/water) | 7.68calc.Computed value |
| Topological polar surface area | 83.83 Ųcalc.Computed value |
| Hydrogen bond donors | 2calc.Computed value |
| Hydrogen bond acceptors | 5calc.Computed value |
| Rotatable bonds | 1calc.Computed value |
| Heavy atoms | 47calc.Computed value |
| Rings | 8calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.67calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 11calc.Computed value |
| Components | 2calc.Computed value |
| Lipinski rule of five | Fails (2 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Loestrin suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
Post one free request and suppliers who make or trade Loestrin can send you quotes. Your contact details stay private until you accept a quote.
Loestrin price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Loestrin is traded under.
Oestrogens and progestogens
- China42.9%
- Italy18.4%
- Netherlands8.9%
- India * partner reported12.1%
- United States11.0%
- Belgium8.3%
* Partner reported figures, a lower bound.
The HS code shown for Loestrin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Loestrin, based on the data on this page
What is Loestrin?
What is the CAS number of Loestrin?
What is the molecular formula and weight of Loestrin?
Is Loestrin hazardous?
What is the HS code of Loestrin?
Where can I buy Loestrin?
What is the price of Loestrin?
Guides for buyers
Practical guides that help when you source, ship or handle Loestrin
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
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