Malathion
Also known as Carbophos, Carbofos, Mercaptothion
Key facts
What buyers check first
- Appearance
- Colorless or slightly yellow
- Melting point
- 3.9 °C
- Boiling point
- 60 °C
- Density
- 1.2076 g/cm³ at 20 °C
- Flash point
- >162.8
- HS code
- 293090
- Category
- Insecticides and acaricides
- UN number
- UN 3018
What is Malathion?
Plain description, key identifiers and synonyms
Diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate is a diester that is diethyl succinate in which position 2 is substituted by a (dimethoxyphosphorothioyl)thio group. It is an ethyl ester, an organic thiophosphate and a diester. It is functionally related to a diethyl 2-sulfanylbutanedioate.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- diethyl 2-dimethoxyphosphinothioylsulfanylbutanedioate
- CAS number
- 121-75-5 CAS number cross-checked
- EC number
- 204-497-7
- Molecular formula
- C10H19O6PS2
- UNII
- U5N7SU872W
- InChIKey
- JXSJBGJIGXNWCI-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3
- SMILES (canonical and isomeric)
- CCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC
Synonyms
- Carbophos
- Carbofos
- Mercaptothion
- Karbofos
- Cythion
- Prioderm
- Phosphothion
- Carbetox
- Ethiolacar
- Maldison
- Sadophos
- Oleophosphothion
- Ovide
- Chemathion
- Malaspray
- Malathon
- Fyfanon
- Malamar
- Sadofos
- Carbetovur
- Fosfothion
- Fosfotion
- Cimexan
- Malafor
- Malagran
Show all 39 synonymsShow fewer synonyms
- Malakill
- Malaphos
- Malatol
- Malatox
- Malphos
- Moscarda
- Sumitox
- Etiol
- Taskil
- Emmatos extra
- Ortho Malathion
- Siptox I
- Extermathion
- Mercaptotion
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Colorless or slightly yellowexp.Measured value |
|---|---|
| Odour | Skunk-like odorexp.Measured value |
| Melting point | 3.9 °Cexp.Measured value |
| Boiling point | 60 °Cexp.Measured value |
| Density | 1.2076 g/cm³ at 20 °Cexp.Measured value |
| Flash point | >162.8exp.Measured value |
| Solubility | In water, 143 mg/L at 20 °Cexp.Measured value |
| Vapour pressure | 3.97 × 10⁻⁵ mm Hg at 30 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 330.36 g/molcalc.Computed value |
|---|---|
| Exact mass | 330.0361 Dacalc.Computed value |
| LogP (octanol/water) | 2.12calc.Computed value |
| Topological polar surface area | 71.06 Ųcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 8calc.Computed value |
| Rotatable bonds | 9calc.Computed value |
| Heavy atoms | 19calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.8calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 1calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H317May cause an allergic skin reaction.
- H400Very toxic to aquatic life.
- H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (14)
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P272Contaminated work clothing should not be allowed out of the workplace.
- P273Avoid release to the environment.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P302 + P352If on skin: Wash with plenty of water.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P333 + P317If skin irritation or rash occurs: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P391Collect spillage.
- P501Dispose of contents and container in accordance with local regulations.
- UN number
- UN 3018
- Transport hazard class
- 9
- Packing group
- III
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidMalathion suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- India, Mumbai ManufacturerUnclaimed profileMalathionGrade, purity and minimum order on requestPrice on request
- China, Lianyungang ManufacturerUnclaimed profileMalathionGrade, purity and minimum order on requestPrice on request
- Germany, HamburgUnclaimed profileMalathionGrade, purity and minimum order on requestPrice on request
- China, ShenzhenUnclaimed profileMalathionGrade, purity and minimum order on requestPrice on request
- India ManufacturerUnclaimed profileMalathionGrade, purity and minimum order on requestPrice on request
- India, IndoreUnclaimed profileMalathionGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileMalathionGrade, purity and minimum order on requestPrice on request
- China, NanjingUnclaimed profileMalathionGrade, purity and minimum order on requestPrice on request
- Price on request
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Where suppliers are based
122 suppliers in 22 countries
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Malathion price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Insecticide for non agricultural uses-eg, aquatic uses, livestock, poultry, home & garden uses, lawns, turf & ornamentals, commercial, household & industrial uses, cotton, vegetables, & citrus, other field crops-eg, corn & sorghum, deciduous fruits/nuts & wheat, storage bins & transportation equipment acaricide.
Malathion has been employed in aerial spraying of relatively populous areas for control of citrus orchard-destructive Mediterranean fruit flies and mosquitoes.
It is used widely in agriculture for various food and feed crops, homeowner outdoor uses, ornamental nursery stock, building perimeters, pastures and rangeland, and regional pest eradication programs.
Use classes: Organophosphates and carbamates, Insecticides.
Industries and functions
Pharmacological actions
- Cholinesterase Inhibitors
- Insecticides
Roles
- acaricide
- agrochemical
- antiinfective agent
- antiparasitic agent
- enzyme inhibitor
- insecticide
- pediculicide
- pesticide
- pharmaceutical
- pro-agent
- proinsecticide
- propesticide
- scabicide
Functional uses
- Biocide
Pharmacology
Malathion is a Cholinesterase Inhibitor. The mechanism of action of malathion is as a Cholinesterase Inhibitor.
How it is made
Malathion is typically manufactured using a condensation reaction (at 70-80 °C) of O,O-dimethyl phosphorodithioic acid and diethyl maleate or diethyl fumarate in the presence of hydroquinone.
The feed materials for malathion manufacture are O,O-dimethyl phosphorodithioic acid and diethyl maleate or fumarate. ... An antipolymerization agent such as hydroquinone may be added to the reaction mixture to inhibit polymerization of the maleate or fumarate compound under reaction conditions. This reaction is preferably carried out at temperatures within the range of 20 deg to 150 °C.
Read more
This reaction is preferably carried out at atmospheric pressure. ... The reaction is preferably carried out in a solvent such as the low molecular weight aliphatic monohydric alcohols, ketones, aliphatic esters, aromatic hydrocarbons or trialkyl phosphates. ... A stirred, jacketed reactor of conventional design may be used. After cooling, the reaction mixture may be taken up in benzene. It is then washed with 10% Na2CO3 and with water. The organic layer is dried over anhydrous Na2SO4, filtered and concentrated in vacuo to give the final product as residue.
Regulatory status
Inventories, regulations and trade controls that list this substance
Europe
- EU harmonised classification (CLP Annex VI)Index no: 015-041-00-X
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Malathion is traded under.
Organo-sulphur compounds, other
- China40.7%
- United States10.9%
- Japan9.3%
- United States13.3%
- Brazil12.6%
- China6.6%
The HS code shown for Malathion is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Stereoisomers and isotopic forms
Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)
![1,4-Di(ethyl-1,1,2,2,2-d5) 2-[(dimethoxyphosphinothioyl)thio]butanedioate chemical structure, C10H19O6PS2, CAS 347841-48-9](/s/JXSJBGJIGXNWCI-JKSUIMTKSA-N.svg)
Similar structures
Nearest neighbours by Morgan fingerprint Tanimoto similarity
Same formula isomers
Different compounds that share this molecular formula
Frequently asked questions
Quick answers about Malathion, based on the data on this page
What is Malathion?
What is the CAS number of Malathion?
What is the molecular formula and weight of Malathion?
What is Malathion used for?
Is Malathion hazardous?
What is the HS code of Malathion?
Where can I buy Malathion?
Where can I buy Malathion in India?
What is the price of Malathion?
Guides for buyers
Practical guides that help when you source, ship or handle Malathion
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, Trade and logisticsShipping dangerous goods: UN numbers, classes and packing groupsHow the UN dangerous goods system works for chemicals, from the nine classes and UN numbers to packing groups, UN packaging marks, labels, documents and segregation.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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