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Alkaloids

Mescaline

Also known as Mescalin, 3,4,5-Trimethoxyphenethylamine, Mezcaline

CAS 54-04-6Formula C11H17NO3Molar mass 211.26 g/molEC 200-190-7
GHS signal word: Warning. Pictograms: Harmful or irritant Prohibited, not for trade
Why it is not for trade
Mescaline chemical structure, C11H17NO3, CAS 54-04-6
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals . Takes up CO2 from the air and forms crystalline carbonate
Melting point
35 to 36
Boiling point
180 °C
Solubility
Moderately soluble in water, soluble in chloroform, benzene. Practically insoluble in et…
HS code
293979
Category
Alkaloids

What is Mescaline?

Plain description, key identifiers and synonyms

Mescaline is a phenethylamine alkaloid that is phenethylamine substituted at positions 3, 4 and 5 by methoxy groups. It has a role as a hallucinogen and a plant metabolite. It is a phenethylamine alkaloid, a primary amino compound and a member of methoxybenzenes. It is a conjugate base of a mescalinium.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(3,4,5-trimethoxyphenyl)ethanamine
CAS number
54-04-6 CAS number cross-checked
EC number
200-190-7
Molecular formula
C11H17NO3
UNII
RHO99102VC
MDL number
MFCD00128240
InChIKey
RHCSKNNOAZULRK-UHFFFAOYSA-N
InChI
InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
SMILES (canonical and isomeric)
COC1=CC(=CC(=C1OC)OC)CCN

Synonyms

  • Mescalin
  • 3,4,5-Trimethoxyphenethylamine
  • Mezcaline
  • 2-(3,4,5-Trimethoxyphenyl)ethanamine
  • 3,4,5-Trimethoxybenzeneethanamine
  • 3,4,5-Trimethoxyphenylethylamine
  • Benzeneethanamine, 3,4,5-trimethoxy-
  • Trimethoxyphenethylamine
  • Tmpea
  • Mezcalin
  • mescalina
  • mezcalina
  • Meskalin
  • 2-(3,4,5-trimethoxy-phenyl)-ethylamine
  • Mescline
  • Mezcline
  • 2-(3,4,5-Trimethoxyphenyl)ethylamine
  • Phenethylamine, 3,4,5-trimethoxy-
  • Ethane, 1-amino-2-(3,4,5-trimethoxyphenyl)-
  • M (psychedelic)
  • 1-amino-2-(3,4,5-trimethoxyphenyl)ethane
  • 3,4,5-trimethoxy-phenylethylamine
  • DEA No. 7381
  • 3,4,5-trimethoxyphenethyl-amine
  • 2-(3,4,5-Trimethoxyphenyl)ethan-1-amine
Show all 33 synonyms
  • Constituent of Peyote cacti
  • 3,5-Trimethoxyphenethylamine
  • DivK1c_000984
  • 3,5-Trimethoxyphenylethylamine
  • Ethane,4,5-trimethoxyphenyl)-
  • 3,4,5-trimethoxy-phenethylamine
  • Benzeneethanamine,4,5-trimethoxy-
  • 3,4,5-Trimethoxy-b-phenethylamine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals . Takes up CO2 from the air and forms crystalline carbonateexp.
Melting point
35 to 36exp.
Boiling point
180 °Cexp.
Solubility
Moderately soluble in water, soluble in chloroform, benzene. Practically insoluble in ether, petroleum ether.exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
211.26 g/molcalc.
Exact mass
211.1208 Dacalc.
LogP (octanol/water)
1.21calc.
Topological polar surface area
53.71 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
5calc.
Heavy atoms
15calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.46calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Mescaline suppliers

Trading restrictions apply to this substance

Psychotropic substance

Mescaline is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971 Schedule I

Our policy on controlled substances

Mescaline price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Therapeutic use: Experimental psychotomimetic.

Biochemical and medical research, hallucinogenic drug.

The legal use of peyote and mescaline in the United States today is limited to Indian tribes in the Native American Church who use the peyote as part of their religious ceremony.

Pharmacological actions

  • Hallucinogens
  • Serotonin Receptor Agonists

Roles

  • central nervous system drug
  • eukaryotic metabolite
  • hallucinogen
  • metabolite
  • pharmaceutical
  • plant metabolite
  • psychotropic drug

How it is made

Psychotomimetic alkaloid isolated from peyote (mescal buttons), the flowering heads of Lophophora williamsii (Lemaire) Cout., Cactaceae

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Mescaline is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971 Schedule I

Our policy on controlled substances

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: 3,4,5-Trimethoxyphenethylamine (Mescaline) and its salts, Ref no: 222, Annex ref: II/222

Controls

  • US DEA controlled substance or listed chemical
  • Controlled psychotropic substance

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mescaline is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Mescaline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mescaline, based on the data on this page

What is Mescaline?

Mescaline is a phenethylamine alkaloid that is phenethylamine substituted at positions 3, 4 and 5 by methoxy groups. It has a role as a hallucinogen and a plant metabolite. It is a phenethylamine alkaloid, a primary amino compound and a member of methoxybenzenes. It is a conjugate base of a mescalinium.

What is the CAS number of Mescaline?

The CAS registry number of Mescaline is 54-04-6.

What is the molecular formula and weight of Mescaline?

The molecular formula of Mescaline is C11H17NO3 and its molar mass is 211.26 g/mol.

What is Mescaline used for?

Therapeutic use: Experimental psychotomimetic. Biochemical and medical research, hallucinogenic drug. The legal use of peyote and mescaline in the United States today is limited to Indian tribes in the Native American Church who use the peyote as part of their religious ceremony.

Is Mescaline hazardous?

Mescaline carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Mescaline?

Mescaline is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Mescaline on CompoundList?

No. Mescaline is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Mescaline

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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