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Cardiovascular and metabolic drugs

Methoxamine

Also known as Methoxamin, 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol, Methoxamedrine

CAS 390-28-3Formula C11H17NO3Molar mass 211.26 g/molEC 206-867-3
2 suppliers listed
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Methoxamine chemical structure, C11H17NO3, CAS 390-28-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
390-28-3
Formula
C11H17NO3
Molar mass
211.26 g/mol
EC number
206-867-3
HS code
292250
Category
Cardiovascular and metabolic drugs

What is Methoxamine?

Plain description, key identifiers and synonyms

Methoxamine is an amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group and the phenyl ring is 2- and 5-substituted with methoxy groups. It is an antihypotensive agent (pressor), an agonist acting directly at alpha-adrenoceptors with selectivity for the alpha-1 adrenoceptor subtype similar to phenylephrine. It has a role as an antihypotensive agent and an alpha-adrenergic agonist.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
CAS number
390-28-3 CAS number cross-checked
EC number
206-867-3
Molecular formula
C11H17NO3
MDL number
MFCD00242998
InChIKey
WJAJPNHVVFWKKL-UHFFFAOYSA-N
InChI
InChI=1S/C11H17NO3/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3/h4-7,11,13H,12H2,1-3H3
SMILES (canonical and isomeric)
CC(C(C1=C(C=CC(=C1)OC)OC)O)N

Synonyms

  • Methoxamin
  • 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
  • Methoxamedrine
  • Pseudomethoxamine
  • Metossamina
  • Benzenemethanol, alpha-(1-aminoethyl)-2,5-dimethoxy-
  • Methoxamedrin
  • Vasoxin
  • Wellcome, Metoxamine
  • 2,5-Dimethoxynorephedrine
  • Metoxamina
  • alpha-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol
  • Benzyl alcohol, alpha-(1-aminoethyl)-2,5-dimethoxy-
  • Methoxamine (BAN)
  • 2-amino-1-[2,5-bis(methyloxy)phenyl]propan-1-ol
  • Sdccgsbi-0050747.p004
  • 2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol
  • 2-Amino-1-(2,5-dimethoxyphenyl)-1-propanol #
  • (.+/-.)-alpha-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol
  • 2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol (methoxamine)
  • 2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol(Methoxamine)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
211.26 g/molcalc.
Exact mass
211.1208 Dacalc.
LogP (octanol/water)
1.08calc.
Topological polar surface area
64.71 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
15calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.46calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Methoxamine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 2 suppliers
  • OChem Inc
    United States, West ChicagoUnclaimed profile
    MethoxamineGrade, purity and minimum order on request
    Price on request
    View
  • TimTec
    United States, KissimmeeUnclaimed profile
    MethoxamineGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

2 suppliers in 1 country

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Methoxamine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Adrenergic alpha-1 Receptor Agonists
  • Sympathomimetics
  • Vasoconstrictor Agents

Roles

  • adrenergic agent
  • adrenergic agonist
  • alpha-adrenergic agonist
  • alpha-adrenergic drug
  • antihypotensive agent
  • cardiovascular drug
  • neurotransmitter agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Methoxamine is traded under.

HS 2922.50Indicative HS code

Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function

World exports in 2024
$3.29B
−5.9% vs 2023, imports $3.19B
2019 to 2024
Top exporters
  1. China39.2%
  2. United Kingdom27.1%
  3. India * partner reported4.8%
Top importers
  1. United States20.7%
  2. Germany7.6%
  3. Italy6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Methoxamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Methoxamine, based on the data on this page

What is Methoxamine?

Methoxamine is an amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group and the phenyl ring is 2- and 5-substituted with methoxy groups.

What is the CAS number of Methoxamine?

The CAS registry number of Methoxamine is 390-28-3.

What is the molecular formula and weight of Methoxamine?

The molecular formula of Methoxamine is C11H17NO3 and its molar mass is 211.26 g/mol.

What is Methoxamine used for?

Use classes: Pharmaceuticals.

Is Methoxamine hazardous?

No GHS hazard classification for Methoxamine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Methoxamine?

Methoxamine is usually classified under HS code 292250 (Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Methoxamine?

CompoundList lists 2 suppliers of Methoxamine in United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Methoxamine?

Suppliers quote Methoxamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Methoxamine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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