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Coenzymes and cofactors

Mesna

Also known as Sodium 2-mercaptoethanesulfonate, Mesnex, Uromitexan

CAS 19767-45-4Formula C2H5NaO3S2Molar mass 164.18 g/molEC 243-285-9
GHS signal word: Danger. Pictograms: Corrosive, Harmful or irritant 99 suppliers listed Drug substance
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Mesna chemical structure, C2H5NaO3S2, CAS 19767-45-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
19767-45-4
Formula
C2H5NaO3S2
Molar mass
164.18 g/mol
EC number
243-285-9
HS code
293090
Category
Coenzymes and cofactors

What is Mesna?

Plain description, key identifiers and synonyms

Mesna is an organosulfonic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
sodium 2-sulfanylethanesulfonate
CAS number
19767-45-4 CAS number cross-checked
EC number
243-285-9
Molecular formula
C2H5NaO3S2
UNII
NR7O1405Q9
MDL number
MFCD00007535
InChIKey
XOGTZOOQQBDUSI-UHFFFAOYSA-M
InChI
InChI=1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1
SMILES (canonical and isomeric)
C(CS(=O)(=O)[O-])S.[Na+]

Synonyms

  • Sodium 2-mercaptoethanesulfonate
  • Mesnex
  • Uromitexan
  • 2-Mercaptoethanesulfonic acid sodium salt
  • Mitexan
  • Mistabron
  • Mesnum
  • Sodium 2-mercaptoethane sulfonate
  • Mistabronco
  • Coenzyme M sodium salt
  • Ethanesulfonic acid, 2-mercapto-, monosodium salt
  • Sodium 2-Mercaptoethanesulphonate
  • 2 Mercaptoethanesulfonate
  • Mexan
  • Ausobronc
  • Filesna
  • Mucolene
  • Mesnil
  • Ziken
  • Mesna Injection
  • MESNA cell
  • mercaptoethanesulfonate
  • mercaptoethane sulfonate
  • ASTAD 7093
  • ASTA D 7093
Show all 37 synonyms
  • 2-Mercaptoethanesulphonate, Sodium
  • UCB 3983
  • 2-Mercaptoethanesulfonate, Sodium Salt
  • 2-sulfanylethane-1-sulfonic acid
  • sodium 2-sulfanylethane-1-sulfonate
  • C2H5NaO3S2
  • sodium, 2-sulfanylethanesulfonate
  • 2-Mercaptoethanesulfonate, sodium
  • Ethanesulfonic acid, 2-mercapto-, sodium salt (1:1)
  • Sodium 2-mercaptoethanesulfonate, Mesnum
  • Mesna, Sodium 2-sulfanylethanesulfonate
  • Natrium 2-mercaptoethansulfonat

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
164.18 g/molcalc.
Exact mass
163.9578 Dacalc.
LogP (octanol/water)
-3.53calc.
Topological polar surface area
57.2 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
8calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H314Causes severe skin burns and eye damage.
  • H315Causes skin irritation.
  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (23)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P352If on skin: Wash with plenty of water.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P363Wash contaminated clothing before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Mesna suppliers

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All 99 suppliers
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Where suppliers are based

99 suppliers in 15 countries

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Mesna price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Protective Agents

Roles

  • anti-anaemic agent
  • anti-obesity agent
  • antifibrotic agent
  • antineoplastic agent
  • immunomodulator
  • immunosuppressive agent
  • pharmaceutical
  • protective agent
  • renoprotective agent

Pharmacology

Mesna is a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. (NCI04)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mesna is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Mesna is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mesna, based on the data on this page

What is Mesna?

Mesna is an organosulfonic acid.

What is the CAS number of Mesna?

The CAS registry number of Mesna is 19767-45-4.

What is the molecular formula and weight of Mesna?

The molecular formula of Mesna is C2H5NaO3S2 and its molar mass is 164.18 g/mol.

What is Mesna used for?

Known uses and roles of Mesna include anti-anaemic agent, anti-obesity agent, antifibrotic agent, antineoplastic agent, immunomodulator and 5 more.

Is Mesna hazardous?

Mesna carries the GHS signal word "Danger". Main hazards: causes severe skin burns and eye damage, causes skin irritation, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Mesna?

Mesna is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Mesna?

CompoundList lists 99 suppliers of Mesna in United States, China, Germany, United Kingdom and 11 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Mesna in India?

4 suppliers in India list Mesna on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Mesna?

Suppliers quote Mesna on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Mesna

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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