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Central nervous system drugs

Metixene

Also known as Methixene, Tremaril, Methixart

CAS 4969-02-2Formula C20H23NSMolar mass 309.48 g/molEC 225-610-6
GHS signal word: Warning. Pictograms: Harmful or irritant, Hazardous to the environment 1 supplier listed
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Metixene chemical structure, C20H23NS, CAS 4969-02-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
4969-02-2
Formula
C20H23NS
Molar mass
309.48 g/mol
EC number
225-610-6
HS code
293499
Category
Central nervous system drugs

What is Metixene?

Plain description, key identifiers and synonyms

Metixene is a member of piperidines and a member of thioxanthenes. It has a role as a histamine antagonist, an antiparkinson drug and a muscarinic antagonist.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine
CAS number
4969-02-2 CAS number cross-checked
EC number
225-610-6
Molecular formula
C20H23NS
UNII
32VY6L26ZW
InChIKey
MJFJKKXQDNNUJF-UHFFFAOYSA-N
InChI
InChI=1S/C20H23NS/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20/h2-5,8-11,15,18H,6-7,12-14H2,1H3
SMILES (canonical and isomeric)
CN1CCCC(C1)CC2C3=CC=CC=C3SC4=CC=CC=C24

Synonyms

  • Methixene
  • Tremaril
  • Methixart
  • 1-Methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine
  • Methixen
  • Metixeno
  • Metisene
  • Metixenum
  • Atosil
  • Piperidine, 1-methyl-3-(9H-thioxanthen-9-ylmethyl)-
  • Metixene (INN)
  • 60 SJ 1977
  • 1-Methyl-3-[(9H-thioxanthen-9-yl)methyl]piperidine
  • 1-Methyl-3-(thioxanthen-9-ylmethyl) piperidine
  • Piperidine, 1-methyl-3-(thioxanthen-9-ylmethyl)-
  • Methixene hydrochloride hydrete
  • Methyloxan
  • Raunana
  • Tremoquil
  • Dalpan
  • Metixene (*hydrochloride*)
  • Tremonil (*hydrochloride*)
  • Methixene (*hydrochloride*)
  • 60 SJ 1977 (*hydrochloride*)
  • 9-(1'-Methylpiperidine-3'-methyl)thioxanthene
Show all 27 synonyms
  • 1-Methyl-3-(thioxanthen-9-ylmethyl)-1-piperidine
  • 1-Methyl-3-(9H-thioxanthen-9-yl-methyl)piperidine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
309.48 g/molcalc.
Exact mass
309.1551 Dacalc.
LogP (octanol/water)
5.02calc.
Topological polar surface area
3.24 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
22calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)Sc1ccccc1C2CC1CCCNC1

c1ccc2c(c1)Sc1ccccc1C2CC1CCCNC1

4 rings, 21 atoms, the Piperidine, 3-(thioxanthen-9-ylmethyl)- ring system.

6 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Metixene suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

1 supplier in 1 country

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Metixene price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Roles

  • antagonist
  • antidyskinesia agent
  • antiparkinson drug
  • cholinergic antagonist
  • cholinergic drug
  • histamine antagonist
  • histaminergic drug
  • muscarinic antagonist
  • neurotransmitter agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Metixene is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Metixene is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Metixene, based on the data on this page

What is Metixene?

Metixene is a member of piperidines and a member of thioxanthenes. It has a role as a histamine antagonist, an antiparkinson drug and a muscarinic antagonist.

What is the CAS number of Metixene?

The CAS registry number of Metixene is 4969-02-2.

What is the molecular formula and weight of Metixene?

The molecular formula of Metixene is C20H23NS and its molar mass is 309.48 g/mol.

What is Metixene used for?

Known uses and roles of Metixene include cns agents in pharmaceuticals, antagonist, antidyskinesia agent, antiparkinson drug, cholinergic antagonist and 6 more.

Is Metixene hazardous?

Metixene carries the GHS signal word "Warning". Main hazards: harmful if swallowed, very toxic to aquatic life, very toxic to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Metixene?

Metixene is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Metixene?

CompoundList lists 1 supplier of Metixene in India. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Metixene in India?

1 supplier in India list Metixene on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Metixene?

Suppliers quote Metixene on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Metixene

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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