CompoundList
Sign in
Screening compounds

Metofoline

Also known as Methopholine, Metopholine, Versidyne

CAS 2154-02-1Formula C20H24ClNO2Molar mass 345.87 g/mol
Get quotes Safety data
Metofoline chemical structure, C20H24ClNO2, CAS 2154-02-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
2154-02-1
Formula
C20H24ClNO2
Molar mass
345.87 g/mol
HS code
293349
Category
Screening compounds

What is Metofoline?

Plain description, key identifiers and synonyms

Metofoline is a member of isoquinolines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-[2-(4-chlorophenyl)ethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
CAS number
2154-02-1 CAS number cross-checkedOther or deprecated CAS: 14415-95-3, 180003-15-0
Molecular formula
C20H24ClNO2
UNII
72L4ZT2W1P, T8093YH1A3
InChIKey
YBCPYHQFUMNOJG-UHFFFAOYSA-N
InChI
InChI=1S/C20H24ClNO2/c1-22-11-10-15-12-19(23-2)20(24-3)13-17(15)18(22)9-6-14-4-7-16(21)8-5-14/h4-5,7-8,12-13,18H,6,9-11H2,1-3H3
SMILES (canonical and isomeric)
CN1CCC2=CC(=C(C=C2C1CCC3=CC=C(C=C3)Cl)OC)OC

Synonyms

  • Methopholine
  • Metopholine
  • Versidyne
  • ARC I-K-1
  • NIH 7672
  • Ro 4-1778/1
  • 1-(p-Chlorophenethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoline
  • ISOQUINOLINE, 1-(p-CHLOROPHENETHYL)-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-
  • Mesofolin
  • Metofolina
  • Metofoline, (-)-
  • Methopholine, (-)-
  • 1-[2-(4-chlorophenyl)ethyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
  • ARC 1-K-1
  • Methopholine (USAN)
  • Ro 4-1778
  • Ro 41778/1
  • NIH 7672, ARC-1-K-1, ARC I-K-1
  • Isoquinoline, 1-(2-(4-chlorophenyl)ethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-
  • Metofoline, (+)-
  • 1-[2-(4-chlorophenyl)ethyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
  • Isoquinoline, 1-(2-(4-chlorophenyl)ethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (-)-
  • Methopholine, (+)-
  • Metofolinum
  • 1-(2-(4-Chlorophenyl)ethyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
Show all 32 synonyms
  • 1-(p-Chlorophenethyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
  • NIOSH/NX4948000
  • Isoquinoline, 1-(2-(4-chlorophenyl)ethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (+)-
  • 1-(p-Chlorophenethyl)-2-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
  • 1-(p-Chlorophenethyl)-6,2,3,4-tetrahydroisoquinoline
  • Isoquinoline,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-
  • 1-(p-Chlorophenethyl)-2-methyl-6,2,3,4-tetrahydroisoquinoline

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
345.87 g/molcalc.
Exact mass
345.1496 Dacalc.
LogP (octanol/water)
4.52calc.
Topological polar surface area
21.7 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
5calc.
Heavy atoms
24calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(CCC2NCCc3ccccc32)cc1

c1ccc(CCC2NCCc3ccccc32)cc1

3 rings, 18 atoms, the 1-(2-Phenylethyl)-1,2,3,4-tetrahydroisoquinoline ring system.

71 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Metofoline suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

No supplier listings yet

Post one free request and suppliers who make or trade Metofoline can send you quotes. Your contact details stay private until you accept a quote.

Request quotesSell this chemical

Metofoline price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Metofoline is traded under.

HS 2933.49Indicative HS code

Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…

World exports in 2024
$939M
−14.6% vs 2023, imports $1.48B
2019 to 2024
Top exporters
  1. China30.1%
  2. India * partner reported16.7%
  3. Switzerland * partner reported14.1%
Top importers
  1. United Kingdom19.2%
  2. Germany16.0%
  3. Romania8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Metofoline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Metofoline, based on the data on this page

What is Metofoline?

Metofoline is a member of isoquinolines.

What is the CAS number of Metofoline?

The CAS registry number of Metofoline is 2154-02-1. Other or deprecated CAS numbers: 14415-95-3, 180003-15-0.

What is the molecular formula and weight of Metofoline?

The molecular formula of Metofoline is C20H24ClNO2 and its molar mass is 345.87 g/mol.

What is Metofoline used for?

Known uses and roles of Metofoline include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Metofoline hazardous?

No GHS hazard classification for Metofoline is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Metofoline?

Metofoline is usually classified under HS code 293349 (Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Metofoline?

Post a free request on CompoundList and suppliers of Metofoline will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Metofoline?

Suppliers quote Metofoline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Metofoline

Get quotes for Metofoline

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Metofoline
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Metofoline with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/metofoline-2154-02-1" title="Metofoline structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Screening compounds or HS code 293349

Price on request
Free quotes, contact stays private
Get quotes