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Central nervous system drugs

Modafinil

Also known as Provigil, Modiodal, 2-(Benzhydrylsulfinyl)acetamide

CAS 68693-11-8Formula C15H15NO2SMolar mass 273.36 g/molEC 640-968-7
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard 65 suppliers listed Drug substance
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Modafinil chemical structure, C15H15NO2S, CAS 68693-11-8
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White to off-white crystalline powder
Melting point
164 to 166
Solubility
Practically insoluble in water and cyclohexane. Sparingly to slightly soluble in methano…
HS code
293090
Category
Central nervous system drugs
Illustrative photo, off-white crystalline powder in an HDPE jar on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Modafinil?

Plain description, key identifiers and synonyms

2-[(diphenylmethyl)sulfinyl]acetamide is a sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group. It is a sulfoxide and a monocarboxylic acid amide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-benzhydrylsulfinylacetamide
CAS number
68693-11-8 CAS number cross-checkedOther or deprecated CAS: 112111-43-0, 112111-47-4, 112111-49-6
EC number
640-968-7
Molecular formula
C15H15NO2S
UNII
R3UK8X3U3D
MDL number
MFCD00868082
InChIKey
YFGHCGITMMYXAQ-UHFFFAOYSA-N
InChI
InChI=1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)
SMILES (canonical and isomeric)
C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC(=O)N

Synonyms

  • Provigil
  • Modiodal
  • 2-(Benzhydrylsulfinyl)acetamide
  • 2-[(diphenylmethyl)sulfinyl]acetamide
  • 2-benzhydrylsulfinylacetamide
  • modaphonil
  • Modafinilo
  • CRL 40476
  • (+-)-Modafinil
  • Modafinilum
  • Modafinil civ
  • R Modafinil
  • CEP 1538
  • 2-((Diphenylmethyl)sulfinyl)acetamide
  • Acetamide, 2-((diphenylmethyl)sulfinyl)-
  • Thn102 component modafinil
  • 2-(diphenylmethane)sulfinylacetamide
  • Thn-102 component modafinil
  • 2-(di(phenyl)methylsulfinyl)acetamide
  • 2-[di(phenyl)methylsulfinyl]acetamide
  • 2-diphenylmethanesulfinylacetamide
  • 2 Benzhydrylsulfinylacetamide
  • Alertec
  • Modavigil
  • Armodafinil D10
Show all 35 synonyms
  • 2-(Diphenyl-methanesulfinyl)-acetamide
  • Moderateafinil
  • Sparlon
  • (+/-)-Modafinil
  • NH 02D
  • Attenace
  • Modalert
  • Modasomil
  • CRL 40983
  • DEA No. 1680

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White to off-white crystalline powderexp.
Melting point
164 to 166exp.
Solubility
Practically insoluble in water and cyclohexane. Sparingly to slightly soluble in methanol and acetone.exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
273.36 g/molcalc.
Exact mass
273.0824 Dacalc.
LogP (octanol/water)
2.01calc.
Topological polar surface area
60.16 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
5calc.
Heavy atoms
19calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Cc2ccccc2)cc1

c1ccc(Cc2ccccc2)cc1

2 rings, 13 atoms, the Diphenylmethane ring system.

8,982 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H332Harmful if inhaled.
  • H361dSuspected of damaging the unborn child.
  • H373May cause damage to organs through prolonged or repeated exposure.
Precautionary statements (15)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Modafinil suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 65 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

65 suppliers in 14 countries

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Modafinil price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Therapeutic category: CNS Stimulant.

Wakefulness promoting agent used to reduce excessive sleepiness.

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Central Nervous System Stimulants
  • Cytochrome P-450 CYP3A Inducers
  • Wakefulness-Promoting Agents

Functional uses

  • Pharmaceutical

Pharmacology

Modafinil is a Sympathomimetic-like Agent. The physiologic effect of modafinil is by means of Central Nervous System Stimulation and Increased Sympathetic Activity.

How it is made

Preparaton: L. Lafon, DE 2809625, eidem, US 4177290 (1978, 1979 both to Lab. Lafon)

Regulatory status

Inventories, regulations and trade controls that list this substance

Controls

  • US DEA controlled substance or listed chemical

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Modafinil is traded under.

HS 2930.90Indicative HS code

Organo-sulphur compounds, other

World exports in 2024
$5.83B
+0.1% vs 2023, imports $5.93B
2019 to 2024
Top exporters
  1. China40.7%
  2. United States10.9%
  3. Japan9.3%
Top importers
  1. United States13.3%
  2. Brazil12.6%
  3. China6.6%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Modafinil is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Modafinil, based on the data on this page

What is Modafinil?

2-[(diphenylmethyl)sulfinyl]acetamide is a sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

What is the CAS number of Modafinil?

The CAS registry number of Modafinil is 68693-11-8. Other or deprecated CAS numbers: 112111-43-0, 112111-47-4, 112111-49-6.

What is the molecular formula and weight of Modafinil?

The molecular formula of Modafinil is C15H15NO2S and its molar mass is 273.36 g/mol.

What is Modafinil used for?

Therapeutic category: CNS Stimulant. Wakefulness promoting agent used to reduce excessive sleepiness. Use classes: Pharmaceuticals.

Is Modafinil hazardous?

Modafinil carries the GHS signal word "Warning". Main hazards: harmful if swallowed, harmful if inhaled, suspected of damaging the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Modafinil?

Modafinil is usually classified under HS code 293090 (Organo-sulphur compounds, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Modafinil?

CompoundList lists 65 suppliers of Modafinil in United States, India, China, United Kingdom and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Modafinil in India?

12 suppliers in India list Modafinil on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Modafinil?

Suppliers quote Modafinil on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Modafinil

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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