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Screening compounds

Mosapramine

Also known as Clospipramine, Mosapramina, mosapraminum

CAS 89419-40-9Formula C28H35ClN4OMolar mass 479.07 g/mol
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Mosapramine chemical structure, C28H35ClN4O, CAS 89419-40-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
89419-40-9
Formula
C28H35ClN4O
Molar mass
479.07 g/mol
HS code
293339
Category
Screening compounds

What is Mosapramine?

Plain description, key identifiers and synonyms

Mosapramine is a racemate comprising equimolar amounts of (R)- and (S)-mosapramine. It is a second-generation antipsychotic used for the treatment of schizophrenia. It has a role as a dopaminergic antagonist and a second generation antipsychotic. It contains a (S)-mosapramine and a (R)-mosapramine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1'-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]spiro[1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-3,4'-piperidine]-2-one
CAS number
89419-40-9 CAS number cross-checked
Molecular formula
C28H35ClN4O
UNII
04UZQ7O9SJ
InChIKey
PXUIZULXJVRBPC-UHFFFAOYSA-N
InChI
InChI=1S/C28H35ClN4O/c29-23-12-11-22-10-9-21-6-1-2-7-24(21)32(25(22)20-23)16-5-15-31-18-13-28(14-19-31)27(34)30-26-8-3-4-17-33(26)28/h1-2,6-7,11-12,20,26H,3-5,8-10,13-19H2,(H,30,34)
SMILES (canonical and isomeric)
C1CCN2C(C1)NC(=O)C23CCN(CC3)CCCN4C5=CC=CC=C5CCC6=C4C=C(C=C6)Cl

Synonyms

  • Clospipramine
  • Mosapramina
  • mosapraminum
  • 3-chloro-5-(3-(2-oxo-1,2,3,5,6,7,8,8a-octahydroimidazo(1,2-a)pyridine-3-spiro-4'-piperidino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine
  • Spiro(imidazo(1,2-a)pyridine-3(2H),4'-piperidin)-2-one, 1'-(3-(3-chloro-10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)hexahydro-, dihydrochloride
  • 1'-(3-(14-chloro-2-azatricyclo(9.4.0.0^(3,8))pentadeca-1(11),3,5,7,12,14-hexaen-2-yl)propyl)-hexahydro-1H-spiro(imidazo(1,2-a)pyridine-3,4'-piperidin)-2-one
  • Mosapramine (hydrochloride)
  • Clospipramine (hydrochloride)
  • 1'-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]spiro[1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-3,4'-piperidine]-2-one
  • 1'-[3-(3-chloro-10,11-dihydro-5h-dibenzo[b,f]azepin-5-yl)propyl]hexahydro-2h-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one
  • Mosapramine (INN)
  • 1'-(3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)hexahydro-2H-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one
  • (+-)-1'-(3-(3-Chloro-10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)hexahydrospiro(imidazo(1,2-a)pyridine-3(2H),4'-piperidin)-2-one
  • (+/-)-1'-(3-(3-Chloro-10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)hexahydrospiro(imidazo(1,2-a)pyridine-3(2H),4'-piperidin)-2-one
  • (- )-1'-(3-(3-Chloro-10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)hexahydrospiro(imidazo(1,2-a)pyridine-3(2H),4'-piperidin)-2-one.

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
479.07 g/molcalc.
Exact mass
478.2499 Dacalc.
LogP (octanol/water)
4.74calc.
Topological polar surface area
38.82 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
34calc.
Rings
6calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.54calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1NC2CCCCN2C12CCN(CCCN1c3ccccc3CCc3ccccc31)CC2

O=C1NC2CCCCN2C12CCN(CCCN1c3ccccc3CCc3ccccc31)CC2

6 rings, 33 atoms.

3 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Mosapramine suppliers

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Mosapramine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antagonist
  • antipsychotic agent
  • central nervous system depressant
  • central nervous system drug
  • dopaminergic agent
  • dopaminergic antagonist
  • neurotransmitter agent
  • pharmaceutical
  • psychotropic drug
  • second generation antipsychotic
  • tranquilizing drug

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mosapramine is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Mosapramine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mosapramine, based on the data on this page

What is Mosapramine?

Mosapramine is a racemate comprising equimolar amounts of (R)- and (S)-mosapramine. It is a second-generation antipsychotic used for the treatment of schizophrenia. It has a role as a dopaminergic antagonist and a second generation antipsychotic. It contains a (S)-mosapramine and a (R)-mosapramine.

What is the CAS number of Mosapramine?

The CAS registry number of Mosapramine is 89419-40-9.

What is the molecular formula and weight of Mosapramine?

The molecular formula of Mosapramine is C28H35ClN4O and its molar mass is 479.07 g/mol.

What is Mosapramine used for?

Known uses and roles of Mosapramine include building blocks in research and laboratory, screening compounds in research and laboratory, antagonist, antipsychotic agent, central nervous system depressant and 8 more.

Is Mosapramine hazardous?

No GHS hazard classification for Mosapramine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Mosapramine?

Mosapramine is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Mosapramine?

Post a free request on CompoundList and suppliers of Mosapramine will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Mosapramine?

Suppliers quote Mosapramine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Mosapramine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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