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Antibiotics and anti-infectives

Moxidectin

Also known as ProHeart 6, Moxidectina, Moxidectine

CAS 113507-06-5Formula C37H53NO8Molar mass 639.83 g/molEC 635-129-7
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant, Serious health hazard, Hazardous to the environment 73 suppliers listed Drug substance
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Moxidectin chemical structure, C37H53NO8, CAS 113507-06-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
113507-06-5
Formula
C37H53NO8
Molar mass
639.83 g/mol
EC number
635-129-7
HS code
293220
Category
Antibiotics and anti-infectives

What is Moxidectin?

Plain description, key identifiers and synonyms

Moxidectin is a milbemycin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1R,4S,4'E,5'S,6R,6'S,8R,10E,13R,14E,16E,20R,21R,24S)-21,24-dihydroxy-4'-methoxyimino-5',11,13,22-tetramethyl-6'-[(E)-4-methylpent-2-en-2-yl]spiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
CAS number
113507-06-5 CAS number cross-checked
EC number
635-129-7
Molecular formula
C37H53NO8
UNII
NGU5H31YO9
MDL number
MFCD00866560
InChIKey
YZBLFMPOMVTDJY-LSGXYNIPSA-N
InChI
InChI=1S/C37H53NO8/c1-21(2)14-25(6)33-26(7)31(38-42-8)19-36(46-33)18-29-17-28(45-36)13-12-23(4)15-22(3)10-9-11-27-20-43-34-32(39)24(5)16-30(35(40)44-29)37(27,34)41/h9-12,14,16,21-22,26,28-30,32-34,39,41H,13,15,17-20H2,1-8H3/b10-9+,23-12+,25-14+,27-11+,38-31+/t22-,26-,28+,29-,30-,32+,33+,34+,36-,37+/m0/s1
Canonical SMILES
CON=C1CC2(CC3CC(CC=C(C)CC(C)C=CC=C4COC5C(O)C(C)=CC(C(=O)O3)C45O)O2)OC(C(C)=CC(C)C)C1C
Isomeric SMILES
C[C@@H]\1C/C(=C/C[C@@H]2C[C@@H](C[C@@]3(O2)C/C(=N\OC)/[C@@H]([C@H](O3)/C(=C/C(C)C)/C)C)OC(=O)[C@@H]4C=C([C@H]([C@@H]5[C@]4(/C(=C/C=C1)/CO5)O)O)C)/C

Synonyms

  • ProHeart 6
  • Moxidectina
  • Moxidectine
  • Moxidectinum
  • Cydectin
  • CL 301,423
  • CL-301,423
  • Advocate component moxidectin
  • Milbemycin B, 5-O-demethyl-28-deoxy-25-((1E)-1,3-dimethyl-1-butenyl)-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
  • Tauramox
  • MoxiSolv
  • ProHeart
  • Quest Gel
  • ProHeart 12
  • Coraxis
  • Cydectin Oral Drench for Sheep
  • CL 301423
  • Cydectin (moxidectin) Pour-On for Beef and Dairy Cattle
  • (6R,25S)-5-O-Demethyl-28-deoxy-25-((E)-1,3-dimethyl-1-butenyl)-6,28-epoxy-23-oxomilbemycin B 23-(E)-(O-methyloxime)
  • Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
  • Moxidectin CRS
  • (6R,25S)-5-O-Demethyl-28-deoxy-25-[(E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-oxomilbemycin B 23-(E)-(O-methyloxime)
  • Moxidectin (Standard)
  • Moxidectin (USP/INN)
  • Moxidectin for veterinary use
Show all 26 synonyms
  • Moxidectin - Bio-X trade mark

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
639.83 g/molcalc.
Exact mass
639.3771 Dacalc.
LogP (octanol/water)
5.73calc.
Topological polar surface area
116 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
9calc.
Rotatable bonds
3calc.
Heavy atoms
46calc.
Rings
5calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.68calc.
Formal charge
0calc.
Stereocentres
10calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, N=C1CCOC2(C1)CC1CC(CC=CCCC=CC=C3COC4CC=CC(C(=O)O1)C34)O2

N=C1CCOC2(C1)CC1CC(CC=CCCC=CC=C3COC4CC=CC(C(=O)O1)C34)O2

5 rings, 32 atoms.

7 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H301Toxic if swallowed.
  • H319Causes serious eye irritation.
  • H332Harmful if inhaled.
  • H361Suspected of damaging fertility or the unborn child.
  • H372Causes damage to organs through prolonged or repeated exposure.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (21)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P337 + P317If eye irritation persists: Get medical help.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Moxidectin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 73 suppliers
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Where suppliers are based

73 suppliers in 13 countries

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Moxidectin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Pharmacological actions

  • Anthelmintics
  • Antinematodal Agents
  • Insecticides

Roles

  • anthelminthic drug
  • antiinfective agent
  • antiparasitic agent
  • pharmaceutical

Pharmacology

Moxidectin is a macrocyclic lactone derived from Streptomyces cyanogriseus with antiparasitic activity. Upon administration, moxidectin may bind to glutamate-gated chloride channels (GluCl), gamma-aminobutyric acid (GABA) receptors and/or ATP-binding cassette (ABC) transporters expressed on nematode neurons and pharyngeal muscle cells. As a result, neurons or muscle cells remain at either hyperpolarization or depolarization state, thereby resulting in muscle paralysis. Moxidectin reduces the motility and fertility of the parasite and its excretion of immunomodulatory proteins, and inhibits the release of microfilariae.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Moxidectin is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Moxidectin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Moxidectin, based on the data on this page

What is Moxidectin?

Moxidectin is a milbemycin.

What is the CAS number of Moxidectin?

The CAS registry number of Moxidectin is 113507-06-5.

What is the molecular formula and weight of Moxidectin?

The molecular formula of Moxidectin is C37H53NO8 and its molar mass is 639.83 g/mol.

What is Moxidectin used for?

Use classes: Animal Drugs.

Is Moxidectin hazardous?

Moxidectin carries the GHS signal word "Danger". Main hazards: toxic if swallowed, causes serious eye irritation, harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Moxidectin?

Moxidectin is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Moxidectin?

CompoundList lists 73 suppliers of Moxidectin in China, United States, Germany, Spain and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Moxidectin in India?

1 supplier in India list Moxidectin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Moxidectin?

Suppliers quote Moxidectin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Moxidectin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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