CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 32 atoms

8 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
32
Chemicals
8
With full pages
2
Scaffold SMILES

N=C1CCOC2(C1)CC1CC(CC=CCCC=CC=C3COC4CC=CC(C(=O)O1)C34)O2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold N=C1CCOC2(C1)CC1CC(CC=CCCC=CC=C3COC4CC=CC(C(=O)O1)C34)O2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

(1R,4S,5'S,6R,8R,13R,20R,21R,24S)-21,24-Dihydroxy-4'-methoxyimino-5',11,13,22-tetramethyl-6'-(4-methylpent-2-en-2-yl)spiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one chemical structure, C37H53NO8, CAS 119719-24-3
(1R,4S,5'S,6R,8R,13R,20R,21R,24S)-21,24-Dihydroxy-4'-methoxyimino-5',11,13,22-tetramethyl-6'-(4-methylpent-2-en-2-yl)spiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
CAS 119719-24-3C37H53NO8
Moxidectin chemical structure, C37H53NO8, CAS 113507-06-5
Moxidectin
CAS 113507-06-5C37H53NO8
25-Des((1E)-1,3-dimethylbut-1-enyl)-25-((1E)-1-methylprop-1-enyl)moxidectin chemical structure, C35H49NO8, CAS 114041-32-6
25-Des((1E)-1,3-dimethylbut-1-enyl)-25-((1E)-1-methylprop-1-enyl)moxidectin
CAS 114041-32-6C35H49NO8
25-Des((1E)-1,3-dimethylbut-1-enyl)-25-((1E)-1-methylbut-1-enyl)moxidectin chemical structure, C36H51NO8, CAS 114041-23-5
25-Des((1E)-1,3-dimethylbut-1-enyl)-25-((1E)-1-methylbut-1-enyl)moxidectin
CAS 114041-23-5C36H51NO8
Moxidectin, (23Z)- chemical structure, C37H53NO8, CAS 119718-45-5
Moxidectin, (23Z)-
CAS 119718-45-5C37H53NO8
Moxidectin, 8-hydroxymethyl- chemical structure, C37H53NO9, CAS 152830-04-1
Moxidectin, 8-hydroxymethyl-
CAS 152830-04-1C37H53NO9
TF5ZR98Ydv chemical structure, C36H51NO9, CAS 156731-82-7
TF5ZR98Ydv
CAS 156731-82-7C36H51NO9
Moxidectin O-TBS chemical structure, C43H67NO8Si, CAS 1646166-08-6
Moxidectin O-TBS
CAS 1646166-08-6C43H67NO8Si