N-Methylacetamide
Also known as Methylacetamide, Acetamide, N-methyl-, Monomethylacetamide
Key facts
What buyers check first
- Appearance
- Needles
- Melting point
- 28 °C
- Boiling point
- 205 °C
- Density
- 0.9371 @ 25 °C/4 °C
- Flash point
- 108 °C
- HS code
- 292419
- Category
- Cosmetic ingredients

What is N-Methylacetamide?
Plain description, key identifiers and synonyms
N-methylacetamide is a monocarboxylic acid amide that is the N-methyl derivative of acetamide. It has a role as a metabolite. It is a member of acetamides and a monocarboxylic acid amide. It is functionally related to an acetamide.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- N-methylacetamide
- CAS number
- 79-16-3 CAS number cross-checked
- EC number
- 201-182-6
- Molecular formula
- C3H7NO
- UNII
- V0T777481M
- MDL number
- MFCD00008683
- INCI name
- METHYL ACETAMIDE
- InChIKey
- OHLUUHNLEMFGTQ-UHFFFAOYSA-N
- InChI
- InChI=1S/C3H7NO/c1-3(5)4-2/h1-2H3,(H,4,5)
- SMILES (canonical and isomeric)
- CC(=O)NC
Synonyms
- Methylacetamide
- Acetamide, N-methyl-
- Monomethylacetamide
- Methyl acetamide
- N-Methyl acetamide
- Acetamide, methyl-
- N-Monomethylacetamide
- Acetic acid, amide, N-methyl
- N-Acetyl-N-methylamine
- Acetylmethylamine
- N-Methyl-acetamide
- methane, methylcarbamoyl-
- N-Methylacetamide, >=99%
- NML
- n-methylacetamide, acetamide, n-methyl-, nmethylacetamide, n-methylacetamide acetamide, n-methyl- nmethylacetamide
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Needlesexp.Measured value |
|---|---|
| Melting point | 28 °Cexp.Measured value |
| Boiling point | 205 °Cexp.Measured value |
| Density | 0.9371 @ 25 °C/4 °Cexp.Measured value |
| Flash point | 108 °Cexp.Measured value |
| Solubility | In water, 1 × 10⁺⁶ mg/l @ 20 °Cexp.Measured value |
| Vapour pressure | 0.44 mm Hg at 23 °C.exp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 73.10 g/molcalc.Computed value |
|---|---|
| Exact mass | 73.0528 Dacalc.Computed value |
| LogP (octanol/water) | -0.25calc.Computed value |
| Topological polar surface area | 29.1 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 0calc.Computed value |
| Heavy atoms | 5calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.67calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H360DMay damage the unborn child.
Precautionary statements (5)
- P203Obtain, read and follow all safety instructions before use.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P318If exposed or concerned, get medical advice.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidN-Methylacetamide suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China ManufacturerUnclaimed profileN-MethylacetamideGrade, purity and minimum order on requestPrice on request
- China, ZiboUnclaimed profileN-MethylacetamideGrade, purity and minimum order on requestPrice on request
- France, Saint-Thibault-des-VignesUnclaimed profileN-MethylacetamideGrade, purity and minimum order on requestPrice on request
- China, Zibo ManufacturerUnclaimed profileN-MethylacetamideGrade, purity and minimum order on requestPrice on request
- China, NanjingUnclaimed profileN-MethylacetamideGrade, purity and minimum order on requestPrice on request
- Price on request
- United States, WoburnUnclaimed profileN-MethylacetamideGrade, purity and minimum order on requestPrice on request
- China, ShanghaiUnclaimed profileN-MethylacetamideGrade, purity and minimum order on requestPrice on request
- United States, SomervilleUnclaimed profileN-MethylacetamideGrade, purity and minimum order on requestPrice on request
- United States, Buffalo GroveUnclaimed profileN-MethylacetamideGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
33 suppliers in 6 countries
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N-Methylacetamide price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Electrochemistry.
Cosmetic ingredient, INCI name METHYL ACETAMIDE(not reported)
Roles
- metabolite
Cosmetic functions
- Not reported
How it is made
Acetic acid + methylamine (amide formation)
Regulatory status
Inventories, regulations and trade controls that list this substance
Europe
- EU harmonised classification (CLP Annex VI)Index no: 616-053-00-3
Health and food
- EU cosmetic ingredient inventory
- EU Cosmetics Regulation Annex II, prohibited in cosmeticsName: N-Methylacetamide, Ref no: 745, Annex ref: II/745
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code N-Methylacetamide is traded under.
Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other
- United States17.5%
- Germany8.8%
- India * partner reported6.7%
* Partner reported figures, a lower bound.
The HS code shown for N-Methylacetamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about N-Methylacetamide, based on the data on this page
What is N-Methylacetamide?
What is the CAS number of N-Methylacetamide?
What is the molecular formula and weight of N-Methylacetamide?
What is N-Methylacetamide used for?
Is N-Methylacetamide hazardous?
What is the HS code of N-Methylacetamide?
Where can I buy N-Methylacetamide?
What is the price of N-Methylacetamide?
Guides for buyers
Practical guides that help when you source, ship or handle N-Methylacetamide
- Article, FormulationHow to choose a cosmetic emulsifierA structured way to choose an emulsifier for creams and lotions: emulsion type, HLB and its limits, emulsifier families, formula fit, stability testing and what to ask suppliers.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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