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N-Methylacetamide

Also known as Methylacetamide, Acetamide, N-methyl-, Monomethylacetamide

N-Methylacetamide chemical structure, C3H7NO, CAS 79-16-3
2D chemical structure

Key facts

What buyers check first

Appearance
Needles
Melting point
28 °C
Boiling point
205 °C
Density
0.9371 @ 25 °C/4 °C
Flash point
108 °C
HS code
292419
Category
Cosmetic ingredients
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is N-Methylacetamide?

Plain description, key identifiers and synonyms

N-methylacetamide is a monocarboxylic acid amide that is the N-methyl derivative of acetamide. It has a role as a metabolite. It is a member of acetamides and a monocarboxylic acid amide. It is functionally related to an acetamide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-methylacetamide
CAS number
79-16-3 CAS number cross-checked
EC number
201-182-6
Molecular formula
C3H7NO
UNII
V0T777481M
MDL number
MFCD00008683
INCI name
METHYL ACETAMIDE
InChIKey
OHLUUHNLEMFGTQ-UHFFFAOYSA-N
InChI
InChI=1S/C3H7NO/c1-3(5)4-2/h1-2H3,(H,4,5)
SMILES (canonical and isomeric)
CC(=O)NC

Synonyms

  • Methylacetamide
  • Acetamide, N-methyl-
  • Monomethylacetamide
  • Methyl acetamide
  • N-Methyl acetamide
  • Acetamide, methyl-
  • N-Monomethylacetamide
  • Acetic acid, amide, N-methyl
  • N-Acetyl-N-methylamine
  • Acetylmethylamine
  • N-Methyl-acetamide
  • methane, methylcarbamoyl-
  • N-Methylacetamide, >=99%
  • NML
  • n-methylacetamide, acetamide, n-methyl-, nmethylacetamide, n-methylacetamide acetamide, n-methyl- nmethylacetamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Needlesexp.
Melting point
28 °Cexp.
Boiling point
205 °Cexp.
Density
0.9371 @ 25 °C/4 °Cexp.
Flash point
108 °Cexp.
Solubility
In water, 1 × 10⁺⁶ mg/l @ 20 °Cexp.
Vapour pressure
0.44 mm Hg at 23 °C.exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
73.10 g/molcalc.
Exact mass
73.0528 Dacalc.
LogP (octanol/water)
-0.25calc.
Topological polar surface area
29.1 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
5calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.67calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H360DMay damage the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

N-Methylacetamide suppliers

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N-Methylacetamide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Electrochemistry.

Cosmetic ingredient, INCI name METHYL ACETAMIDE(not reported)

Roles

  • metabolite

Cosmetic functions

  • Not reported

How it is made

Acetic acid + methylamine (amide formation)

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 616-053-00-3

Health and food

  • EU cosmetic ingredient inventory
  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: N-Methylacetamide, Ref no: 745, Annex ref: II/745

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code N-Methylacetamide is traded under.

HS 2924.19Indicative HS code

Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$2.38B
−1.7% vs 2023, imports $2.22B
2019 to 2024
Top exporters
  1. China34.7%
  2. Germany12.5%
  3. India * partner reported6.8%
Top importers
  1. United States17.5%
  2. Germany8.8%
  3. India * partner reported6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for N-Methylacetamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about N-Methylacetamide, based on the data on this page

What is N-Methylacetamide?

N-methylacetamide is a monocarboxylic acid amide that is the N-methyl derivative of acetamide. It has a role as a metabolite. It is a member of acetamides and a monocarboxylic acid amide. It is functionally related to an acetamide.

What is the CAS number of N-Methylacetamide?

The CAS registry number of N-Methylacetamide is 79-16-3.

What is the molecular formula and weight of N-Methylacetamide?

The molecular formula of N-Methylacetamide is C3H7NO and its molar mass is 73.10 g/mol.

What is N-Methylacetamide used for?

Electrochemistry.

Is N-Methylacetamide hazardous?

N-Methylacetamide carries the GHS signal word "Danger". Main hazards: may damage the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of N-Methylacetamide?

N-Methylacetamide is usually classified under HS code 292419 (Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy N-Methylacetamide?

CompoundList lists 33 suppliers of N-Methylacetamide in China, United States, Germany, France and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of N-Methylacetamide?

Suppliers quote N-Methylacetamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle N-Methylacetamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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