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Flavonoids and polyphenols

Naringin

Also known as aurantiin, Naringoside, Naringenin 7-O-neohesperidoside

CAS 10236-47-2Formula C27H32O14Molar mass 580.54 g/molEC 233-566-4
GHS signal word: Warning. Pictograms: Harmful or irritant 87 suppliers listed
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Naringin chemical structure, C27H32O14, CAS 10236-47-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
10236-47-2
Formula
C27H32O14
Molar mass
580.54 g/mol
EC number
233-566-4
HS code
293890
Category
Flavonoids and polyphenols

What is Naringin?

Plain description, key identifiers and synonyms

Naringin is a disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a metabolite, an antineoplastic agent and an anti-inflammatory agent. It is a member of 4'-hydroxyflavanones, a (2S)-flavan-4-one, a neohesperidoside, a dihydroxyflavanone and a disaccharide derivative. It is functionally related to a (S)-naringenin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
CAS number
10236-47-2 CAS number cross-checkedOther or deprecated CAS: 1217471-78-7
EC number
233-566-4
Molecular formula
C27H32O14
UNII
N7TD9J649B
MDL number
MFCD00148888
INCI name
NARINGIN
InChIKey
DFPMSGMNTNDNHN-ZPHOTFPESA-N
InChI
InChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1
Canonical SMILES
CC1OC(OC2C(Oc3cc(O)c4c(c3)OC(c3ccc(O)cc3)CC4=O)OC(CO)C(O)C2O)C(O)C(O)C1O
Isomeric SMILES
C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O

Synonyms

  • aurantiin
  • Naringoside
  • Naringenin 7-O-neohesperidoside
  • Naringenin-7-beta-neohesperidoside
  • 5-Hydroxy-2-(4-hydroxyphenyl)-7-(2-O-alpha-L-rhamnopyranosyl-beta-D-glucopyranosyloxy)-4-chromanon
  • Naringenin 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside]
  • 4',5,7-trihydroxyflavanone 7-rhamnoglucoside
  • Naringenin 7-O-(alpha-L-rhamnosyl-(1->2)-beta-D-glucoside)
  • Citrus naringinine
  • Naringenin Glycoside
  • naringenin-7-hesperidoside
  • Naringin (Standard)
  • Naringenin 7-Rhamnoglucoside
  • 4'5-diOH-Flavone-7-rhgluc
  • (s)-yranosyl]oxy]-
  • (2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-1-benzopyran-7-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
  • (2S)-Naringin
  • Naringin CRS
  • yphenyl)chroman-4-one
  • Naringoside (Standard)
  • 7-(2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyloxy)-2,3-dihydro-4',5,7-trihydroxyflavone
  • DivK1c_000247
  • naringenin-7-O-neohesperidoside
  • ACon1_000139
  • Naringenin 7-rhamnoglucoside hydrate
Show all 27 synonyms
  • 4',5,7-Trihydroxyflavanone-7-rhamnoglucoside
  • 4,5,7-Trihydroxyflavanone 7-rhamnoglucoside hydrate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
580.54 g/molcalc.
Exact mass
580.1792 Dacalc.
LogP (octanol/water)
-1.17calc.
Topological polar surface area
225.1 Ųcalc.
Hydrogen bond donors
8calc.
Hydrogen bond acceptors
14calc.
Rotatable bonds
6calc.
Heavy atoms
41calc.
Rings
5calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.52calc.
Formal charge
0calc.
Stereocentres
11calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC(c2ccccc2)Oc2cc(OC3OCCCC3OC3CCCCO3)ccc21

O=C1CC(c2ccccc2)Oc2cc(OC3OCCCC3OC3CCCCO3)ccc21

5 rings, 31 atoms.

15 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Naringin suppliers

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All 87 suppliers
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Where suppliers are based

87 suppliers in 11 countries

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Naringin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name NARINGIN(skin protecting)

Roles

  • anti-inflammatory agent
  • antineoplastic agent
  • metabolite
  • pharmaceutical

Functional uses

  • Flavouring and nutrient
  • Humectant

Cosmetic functions

  • Skin protecting

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Naringin is traded under.

HS 2938.90Indicative HS code

Natural or reproduced by synthesis, other than rutoside (rutin) and its derivatives

World exports in 2024
$1.4B
−8.3% vs 2023, imports $1.35B
2019 to 2024
Top exporters
  1. China49.2%
  2. France * partner reported8.9%
  3. Malaysia6.1%
Top importers
  1. United States22.3%
  2. India * partner reported7.8%
  3. Brazil5.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Naringin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Naringin, based on the data on this page

What is Naringin?

Naringin is a disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a metabolite, an antineoplastic agent and an anti-inflammatory agent.

What is the CAS number of Naringin?

The CAS registry number of Naringin is 10236-47-2. Other or deprecated CAS numbers: 1217471-78-7.

What is the molecular formula and weight of Naringin?

The molecular formula of Naringin is C27H32O14 and its molar mass is 580.54 g/mol.

What is Naringin used for?

Known uses and roles of Naringin include skin conditioning agents in cosmetics and personal care, anti-inflammatory agent, antineoplastic agent, metabolite, pharmaceutical and 3 more.

Is Naringin hazardous?

Naringin carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Naringin?

Naringin is usually classified under HS code 293890 (Glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Naringin?

CompoundList lists 87 suppliers of Naringin in China, United States, United Kingdom, Germany and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Naringin?

Suppliers quote Naringin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Naringin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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